We present a combined geomorphologic, multispectral, and geochemical analysis of crater floor rocks in Jezero crater based on data obtained by the Mast Camera Zoom and SuperCam instruments onboard the NASA Mars 2020 Perseverance rover. The combined data from this analysis together with the results of a comparative study with geologic sites on Earth allows us to interpret the origins of rocks expos

Översättning och bearbetning till nederländska av min biografi om drottning Kristina.

Plant mitochondria represent the largest group of respiring organelles on the planet. Plant mitochondrial messenger RNAs (mRNAs) lack Shine-Dalgarno-like ribosome-binding sites, so it is unknown how plant mitoribosomes recognize mRNA. We show that “mitochondrial translation factors” mTRAN1 and mTRAN2 are land plant–specific proteins, required for normal mitochondrial respiration chain biogenesis.

Production and use of chlorophenols (CPs) are being phased out around the globe, but with considerable lag in some highly populated countries. The process could be incentivized by leading countries sharing their experiences on problems that occurred, including the built environment. We previously reported that Swedish industry and authorities promoted CPs, including pentachlorophenol (PCP), as wooProduction and use of chlorophenols (CPs) are being phased out around the globe, but with considerable lag in some highlypopulated countries. The process could be incentivized by leading countries sharing their experiences on problems thatoccurred, including the built environment. We previously reported that Swedish industry and authorities promoted CPs,including pentachlorophenol (PCP), as wood p

Importance: Longitudinal tau positron emission tomography (PET) is a relevant outcome in clinical trials evaluating disease-modifying therapies in Alzheimer disease (AD). A key unanswered question is whether the use of participant-specific (individualized) regions of interest (ROIs) is superior to conventional approaches where the same ROI (group-level) is used for each participant. Objective: To

PURPOSE: Invasive lobular carcinoma (ILC) is a subtype of breast cancer accounting for 10% of breast tumors. The majority of patients are treated with endocrine therapy; however, endocrine resistance is common in estrogen receptor-positive breast cancer and new therapeutic strategies are needed. Bromodomain and extraterminal inhibitors (BETi) are effective in diverse types of breast cancer but the

4-5.1 Sammanfattning av Glutamat och GABA vid Schizofreni1H-MRS och kronisk schizofreni1H-MRS visar att alla Schizofreni patienter hade ett signifikant lägre N-AcetylAsparagin-syra(NAA) till Kreatin(Cr) nivåförhållande i frontalloben än kontrollerna. Resultaten indikerar att det finns ett samband mellan det Glutamat-erga systemet och patofysiologin vid Schizofreni. (Szulc et al., 2013).GABA och gl

Background: Orthostatic hypotension (OH) has been associated with elevated risk of cardiovascular diseases (CVDs) and dementia risk. To better understand the OH-dementia association, we assessed the associations of OH with CVD and subsequent dementia in older adults and considered the temporality of CVD and dementia onset. Methods: This 15-year population-based cohort study included, at baseline,

Our aim was to compare the inter-rater agreement about transvaginal ultrasonography (TVS) with magnetic resonance imaging (MRI) with regard to diagnosing adenomyosis and for assessing various predefined imaging features of adenomyosis, in the same set of women. The study cohort included 51 women, prospectively, consecutively recruited based on a clinical suspicion of adenomyosis. MRIs and TVS vide

Background: Targeted viral load (VL) testing has been proposed for antiretroviral treatment (ART) monitoring in resource-limited settings. In this study, we have investigated the performance of the host biomarker galectin-9 (Gal-9), alone and in combination with interferon-γ-inducible protein 10 (IP-10), in identifying individuals at increased likelihood of viremia during ART.Setting:Cohort of HIV

Polycrystals illuminated by high-energy X-rays or neutrons produce diffraction patterns in which the measured diffraction peaks encode the individual single crystal strain states. While state of the art X-ray and neutron diffraction approaches can be used to routinely recover per grain mean strain tensors, less work has been produced on the recovery of higher order statistics of the strain distrib

The mechanics of concrete can be understood comprehensively only if its heterogeneous microstructure is considered in experiments and simulations. We combine mesoscale modeling, in-situ X-ray computed tomography imaging, and in-situ 3D X-ray diffraction measurements for one of the first times to investigate the role of heterogeneities on macroscopic and microscopic responses in concrete. The focus

An open source Python package named xrd_simulator, capable of simulating geometrical interactions between a monochromatic X-ray beam and a polycrystalline microstructure, is described and demonstrated. The software can simulate arbitrary intragranular lattice variations of single crystals embedded within a multiphase 3D aggregate by making use of a tetrahedral mesh representation where each elemen

Alzheimer’s disease (AD) is the leading cause of dementia and most common neurodegenerative disease worldwide, but there currently exists no effective treatment that can stop nor slow the progression of the disease. The current dogma in the field postulates that the appearance of extracellular amyloid-beta (Aβ) plaques, a histopathological hallmark of the disease, is the trigger for downstream, de

The current rate of residential building renovations in Europe is inadequate and attributable to the lack of integrated solutions in the market supported by appropriate business models. One-stop-shop (OSS) offers an innovative business approach, and it is acknowledged by the European Commission, in the Directive 2018/844/EU, as a transparent advisory and facilitating tool for the establishment of