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Strategies for enhancing fermentative production of glycerol - A review

The present paper reviews the metabolic basis of different methods for fermentative glycerol production. The most important microbial production organism is the yeast Saccharomyces cerevisiae but other yeast species, as well as molds, algae, and bacteria are of potential interest for glycerol production. A large variety of methods have been applied to increase the fermentative glycerol yield. The

Application of Human Modelling in Health Care Industry

Digital human modelling (DHM) is commonly utilised for vehicle and workplace design in the automotive industry. More rarely are the tools applied in the health care industry, albeit having similar objectives for cost-efficiency and User-centred design processes. The paper illustrates how a DHM tool is modified and utilised to evaluate a bathing system design from caretakers' and caregivers' ergono

Detection of submicroscopic constitutional chromosome aberrations in clinical diagnostics: a validation of the practical performance of different array platforms

For several decades etiological diagnosis of patients with idiopathic mental retardation (MR) and multiple congenital anomalies (MCA) has relied on chromosome analysis by karyotyping. Conventional karyotyping allows a genome-wide detection of chromosomal abnormalities but has a limited resolution. Recently, array-based comparative genomic hybridization (array CGH) technologies have been developed

Interaction between Lamellar (Vesicles) and Nonlamellar Lipid Liquid-Crystalline Nanoparticles as Studied by Time-Resolved Small-Angle X-ray Diffraction

The kinetics of structure change when dispersions of two different types of lipid-based liquid-crystalline phases, one lamellar and one reversed, are mixed has been investigated using synchrotron small-angle X-ray diffraction and ellipsometry. The systems studied were (i) cubic-phase nanoparticles (CPNPs) based on glycerol monooleate (GMO) stabilized with a nonionic block copolymer, Pluronic F-127

Transvaginal Doppler examination for the differential diagnosis of solid pelvic tumors

To evaluate the ability of transvaginal Doppler examination to discriminate between different types of solid pelvic tumors, 55 women scheduled for laparotomy because of a solid pelvic mass underwent transvaginal sonographic examination, including color and spectral Doppler techniques. Arteries in the wall and core of each mass were examined. The histological diagnoses were as follows: uterine myom

Solution Structure of the Ca(2+)-Binding EGF3-4 Pair from Vitamin K-Dependent Protein S: Identification of an Unusual Fold in EGF3(,).

Vitamin K-dependent protein S is a cofactor of activated protein C, a serine protease that regulates blood coagulation. Deficiency of protein S can cause venous thrombosis. Protein S has four EGF domains in tandem; domains 2-4 bind calcium with high affinity whereas domains 1-2 mediate interaction with activated protein C. We have now solved the solution structure of the EGF3-4 fragment of protein

Treatment of three types of landfill leachate with reverse osmosis

Treatment of landfill leachate has gained increasing attention during recent years, and several commercial RO leachate treatment plants have been installed in, e.g., Germany, the Netherlands and Switzerland. in this investigation the influence on membrane performance when treating new types of landfill leachate was studied. Three different types of landfill leachate were included in this study: le

Temporal distance and moral concerns: Future morally questionable behavior is seen as more wrong and evokes stronger prosocial intentions

Prior research on temporal construal has shown that core values become more salient when people think about distant- as compared to near-future events. The present research shows that greater temporal distance of an event also results in greater moral concern. More specifically, it was found that people make harsher moral judgments of others' distant-future morally questionable behavior than near-

A Holocene lacustrine record in the central North Atlantic: proxies for volcanic activity, short-term NAO mode variability, and long-term precipitation changes

Lake and peat corings on three Azores islands in the central North Atlantic, resulted in the discovery of a 6000 year long lacustrine sequence in a small crater lake, Lake Caveiro, on the island of Pico. This island is dominated by Pico mountain (2351 m), Portugal's highest mountain, and the lake site is situated at 903 in asl. Two sediment profiles, one central and one littoral, were sampled. Due

The interactive examination: assessing students' self-assessment ability

BACKGROUND The ability to self-assess one's competence is a crucial skill for all health professionals. The interactive examination is an assessment model aiming to evaluate not only students' clinical skills and competence, but also their ability to self-assess their proficiency. METHODS The methodology utilised students' own self-assessment, an answer to a written essay question and a group disc

Epithelial pathways for luminal entry of bulk plasma

Inflammatory challenges of the airway mucosa cause luminal entry of bulk plasma. Extravasation of plasma is well described but the routes for epithelial passage of plasma are largely unknown. Using colloidal gold (5 nm) as tracer we have now examined the fate of extravasated plasma in the airways. The tracer was given intravenously to anaesthetized, ovalbumin-sensitized guinea-pigs 2min prior to a

The effects of epinephrine/norepinephrine on end-tidal carbon dioxide concentration, coronary perfusion pressure and pulmonary arterial blood flow during cardiopulmonary resuscitation

End-tidal CO2 concentration correlates with pulmonary blood flow during cardiopulmonary resuscitation and has been claimed to be a useful tool to judge the effectiveness of chest compression. A high concentration of end-tidal CO2 has been related to a better outcome. However, most authors have noticed a decrease in end-tidal CO2 concentration after administration of epinephrine, concomitant with a

Mass spectrometric analysis of peptides from an immobilized lipase: focus on oxidative modifications.

Liquid chromatography/tandem mass spectrometry (LC/MS/MS) was used to study the primary structure of immobilized Candida antarctica lipase B (Novozym(R)435) without detaching the enzyme from the carrier. The immobilized enzyme packed in a miniature column was subjected to proteolysis and the peptides released were injected into the mass spectrometer for analysis. The set-up was utilized to determi