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Women with Primary Sjögren´s Syndrome Assessment and Treatment A Physiotherapeutic Perspective

Popular Abstract in Swedish Primärt Sjögrens syndrom är en reumatisk systemsjukdom, som karaktäriseras av nedsatt funktion i vissa körtlar, framför allt i tårkörtlar och spottkörtlar. Detta orsakar huvudsymptomen ögon- och muntorrhet. Patienter med denna sjukdom har även besvär som inte är relaterade till dessa körtlar. Smärta i leder och muskler, extrem trötthet samt nedstämdhet är vanliga problePrimary Sjögren´s syndrome (primary SS) is a systemic autoimmune rheumatic disease characterized by lymphocytic infiltrations in the exocrine glands leading to classic dryness complaints such as dry eyes and dry mouth. Non-exocrine complaints also occur, e.g. fatigue, myalgia and arthralgia, as well as disturbed mood. The overall purpose of this work was, from a physiotherapeutic perspective, to i

Intrauterine or oral administration of levonorgestrel in combination with estradiol to perimenopausal women--effects on lipid metabolism during 12 months of treatment

OBJECTIVE: Limited data concerning serum lipids and lipoproteins are available on the effect of HRT in perimenopausal women, who commonly have marked bleeding disturbances and may have severe climacteric symptoms. Almost all previously published data have utilized a simplified form of lipoprotein analysis, which includes an estimation and not a determination of LDL cholesterol. To delineate the ro

Do dysphagic patients with an absent pharyngeal swallow have a shorter survival than dysphagic patients with pharyngeal swallow? Prognostic importance of a therapeutic videoradiographic swallowing study (TVSS).

Purpose:To study survival in two groups of dysphagic patients - one group unable to elicit the pharyngeal stage of swallow (APS) and another group with pharyngeal swallow (WPS) - and to compare recommendations regarding nutrition and therapeutic strategies based on the therapeutic swallowing study. Material and Methods: In this retrospective study, the records of dysphagic patients who have under

Hyperfine structure and radiative lifetimes in the 3s2n p2P3/2 sequence of Al-27 using time resolved laser spectroscopy

Using time-resolved laser spectroscopy we have determined the hyperfine structure in the 3s2n p2P3/2 sequence of27Al (I=5/2). The magnetic-dipole interaction constants were found to scale withn*-2.85 (n* is the effective principal quantum number) in the investigated regionn=6–12. Significant quadrupole interaction constants were obtained forn=6–9. The measured radiative lifetimes forn=6–12 scale w

Ultrafast singlet energy transfer competes with intersystem crossing in a multi-center transition metal polypyridine complex

Transition metal polypyridine complexes are finding widespread applications within many areas of chemistry. For their light-induced processes, the generally accepted picture is that all function emanates from triplet states because the singlet states initially prepared by light absorption are depopulated via intersystem crossing on the 100-fs time scale, before they are significantly involved in c

Numerical simulations of unsteady fluid flow and heat transfer in a transonic turbine stage

In this work, a numerical study has been performed to simulate the unsteady fluid flow and heat transfer in a transonic high-pressure turbine stage. The main objective of this study is to understand the unsteady flow field and heat transfer in a single transonic turbine stage using an unsteady structured Navier-Stokes solver. For the time accurate computation, a fully implicit time discretization,

Structure and mechanics of growing arterial microvessels from hypertrophied urinary bladder in the rat

Rat bladder hypertrophy, induced by a partial ligation of the urethra, was used to study the accompanying changes of microvascular smooth muscle mechanics, pharmacology and morphology. A segment of a microarterial vessel to the bladder was taken from a defined anatomical location and studied in a wire myograph in vitro at the length for maximal isometric force development (Lmax). After 10 days of

An analytical method to determine the influence of shape deviation on load distribution and mesh stiffness for spur gears

A method for analysing the influence of profile errors upon load-sharing capabilities and mesh stiffness of spur gears is proposed. The analysis is based upon a static, two-dimensional finite element approach. The contacts between mating gear teeth are identified in the deformed state, and the nodal point density permits contact pressure distribution emulation for moderate to high load levels. In

Dppm-substituted ruthenium clusters with capping sulfido and selenido ligands derived from thiourea, tetramethylthiourea and elemental selenium

Treatment of [Ru-3(CO)(10)(mu-dppm)] (4) [dppm = bis(diphenylphosphido)methane] with tetramethylthiourea at 66 degrees C gave the previously reported dihydrido triruthenium cluster [Ru-3(mu-H)(2)(mu(3)-S)(CO)(7)(mu-dppm)] (5) and the new compounds [Ru-3(mu(3)-S)(2)(CO)(7)(mu-dppm)] (6), [Ru-3(mu(3)-S)(CO)(7)(mu(3)-CO)(mu-dppm)] (7) and [Ru-3(mu 3-S)eta(I)-C(NMe2)(2)}(CO)(6)(mu(3)-CO)(mu-dppm)] (8)

Cdc42 is involved in PKCepsilon- and delta-induced neurite outgrowth and stress fibre dismantling.

We have shown that protein kinase C (PKC)epsilon, independently of the catalytic domain, induces outgrowth of cellular processes via its regulatory domain in both neural cells and fibroblasts. This was accompanied by stress fibre loss. Here, we have examined the role of the small GTPases, Rac1, and Cdc42, in these PKC-mediated morphological and cytoskeletal changes. Both constitutively active and

Hepatic lipase activity increases after liver denervation in the rat

We have investigated the effects of hilar denervation of rat liver upon the activity of hepatic lipase determined in tissue extracts. Denervated animals had an enzyme activity of 7.89 +/- 0.37 mU/mg protein, compared to 6.45 +/- 0.43 in sham-operated controls (mean +/- S.E.; P less than 0.05). We conclude that hepatic innervation may contribute to the regulation of hepatic lipase activity.

Theoretical study of the discrimination between O(2) and CO by myoglobin.

Combined quantum chemical and molecular mechanics geometry optimisations have been performed on myoglobin without or with O(2) or CO bound to the haem group. The results show that the distal histidine residue is protonated on the N(varepsilon2) atom and forms a hydrogen bond to the haem ligand both in the O(2) and the CO complexes. We have also re-refined the crystal structure of CO-myoglobin by a

A quantitative autoradiographic study of the heterogeneous activity distribution of different indium-111-labeled radiopharmaceuticals in rat tissues

In light of the increased interest in small scale dosimetry, this paper presents a quantitative autoradiographic method for evaluation of heterogeneous activity distribution in tissues. This was studied in rat tissues after administration of 111In-chloride, -oxine, -tropolone, 111In-labeled homologous blood cells and 111In-anti-CEA-F(ab')2, using quantitative whole-body autoradiography. Quantifica

The mechanism for proton-coupled electron transfer from tyrosine in a model complex and comparisons with Y-z oxidation in photosystem II

In the water-oxidizing reactions of photosystem II (PSII), a tyrosine residue plays a key part as an intermediate electron-transfer reactant between the primary donor chlorophylls (the pigment P-680) and the water-oxidizing Mn cluster. The tyrosine is deprotonated upon oxidation, and the coupling between the proton reaction and electron transfer is of great mechanistic importance for the understan