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Gender Smart Mobility : Concepts, Methods, and Practices

This book presents gender and diversity in smart transport as a cutting-edge issue in urban contexts around the globe. It addresses new challenges and possibilities related to the smart transport sector. It demonstrates how gender and diversity are entangled in concepts and various forms of current smart mobility practices in policy, planning, and innovation. Gender Smart Mobility is presented as

Executive Summary : Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus

BACKGROUND Numerous laboratory tests are used in the diagnosis and management of patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially. An expert committee compiled evidence-based recommendations for laboratory analysis in patients with diabetes. The overall quality of the evidence and the strength of the recommendations wer

Relationships Between Charlson Comorbidity Index Associated Biomarkers and Outcomes Among Participants in the Malmö Diet and Cancer Study

Introduction: The aim was to evaluate two biomarker scores trained to identify comorbidity burden in the prediction of specified chronic morbidities, and mortality in the general population. Methods: Cardiovascular biomarkers were measured in the cardiovascular cohort of the Malmö Diet and Cancer Study. A score of 19 biomarkers associated with Charlson Comorbidity Index (CCI) was created (BSMDC).

Protection-interdiction-restoration for resilient multi-commodity networks

Interdependent critical infrastructure systems represent substantial financial investments and are vital to maintain a fundamental level of social and economic well-being, making them attractive targets for malevolent actors. Many of these infrastructure systems carry multiple products, each with unique needs and importance to different stakeholders. This work extends a tri-level protection-interd

Real-time High-Speed Train Delay Prediction using Seemingly Unrelated Regression Models

Understanding the impact of various factors on train arrival delays is a prerequisite for effective railway traffic operating control and management. Existing studies model the train delay prediction problems using a single, generic equation, restricting their capability in accounting for heterogeneous impacts of spatiotemporal factors on arrival delays as the train travels along its route. The pa

‘Like a torch that enlightens new parents along a narrow and winding path into parenthood’ – Midwives' experiences by an interview study

Background: The core of postnatal care is that midwives recognise the needs of women and new-born babies and provide the highest possible quality of care and medical safety to optimise the health and well-being of new families. The study aimed to describe midwives' experiences in providing postnatal care for families during the first week after the birth of their baby. Methods: An interview study

Dwell-time station-service analysis using a Rasch analysis technique

In order to ensure punctual and robust service, it is vital to have a good understanding of the current performance of a railway network. Several approaches to doing so exist but lack the ability to compare both service and station performance in a single dimension. The study presented here proposes the use of the Rasch analysis technique within an operational context to compare the relative dwell

Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes

Incretin-based therapies are highly successful in combatting obesity and type 2 diabetes1. Yet both activation and inhibition of the glucose-dependent insulinotropic polypeptide (GIP) receptor (GIPR) in combination with glucagon-like peptide-1 (GLP-1) receptor (GLP-1R) activation have resulted in similar clinical outcomes, as demonstrated by the GIPR–GLP-1R co-agonist tirzepatide2 and AMG-133 (ref

Insulin Pump Therapy and Adverse Skin Reactions With Focus on Allergic Contact Dermatitis in Individuals Living With Diabetes Mellitus : A Systematic Review and Clinical-Based Update

Background: The use of insulin pumps (continuous subcutaneous insulin infusion [CSII]) in individuals living with type 1 diabetes (T1D) improves disease control. However, adverse skin reactions may hamper compliance. We aimed to assess the relationship of insulin pumps, particularly that of infusion set therapy, used in children and adults with T1D and dermatitis including allergic contact dermati

L-chondrite body breakup in Ordovician strata in China - A time tie point globally and across the inner solar system

More than a quarter of all meteorites falling on Earth today originate from the breakup of the L-chondrite parent body (LCPB) ∼470 Ma ago, the largest documented asteroid breakup in the past ∼3 Ga. The event had a profound impact on the inner Solar System, resulting in an orders-of-magnitude increase in L-chondritic material in mid-Ordovician sediments on Earth. Here we show based on Ordovician st

Placement of an intrauterine device within 48 hours after second-trimester medical abortion : a randomized controlled trial

Background: International guidelines recommend placement of intrauterine devices immediately after second-trimester medical abortion, but evidence concerning the optimal time for intrauterine device placement is lacking from clinical trials. Objective: This study aimed to investigate effectiveness, safety, and acceptability of intrauterine device placement within 48 hours, compared with placement

A life course perspective on mental disorders and psychopharmacologic drug use among persons living with cerebral palsy

In this study, we investigated the prevalence of mental disorders and the use of psychopharmacologic drugs among individuals with cerebral palsy (CP). We studied how the association between CP and mental illness develops over the life course (between ages 5 and 65 years), and how it varies across disability specific factors (intellectual disability, gross motor function and communicative ability).

A Comprehensive Review Highlighting the Prospects of Phytonutrient Berberine as an Anticancer Agent

Berberine, an isoquinoline alkaloid derived from various medicinal plants, emerges as a potential therapeutic agent against diverse human diseases. It has particularly shown notable anticancer efficacy against breast, colorectal, lung, prostate, and liver cancer. Berberine results in inhibition of cancer cell proliferation, induction of apoptosis, and suppressing angiogenesis, positioning it as a

Sibship size and height before, during, and after the fertility decline : A test of the resource dilution hypothesis

Background: There is still much to learn about the explanation for the often-found negative association between sibship size and different child outcomes. A plausible explanation is resource competition between siblings in larger families, as suggested by the resource dilution hypothesis. Objective: This study contributes to our understanding of these mechanisms by investigating the association be