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High Prevalence of Gestational Diabetes Mellitus in Rural Tanzania-Diagnosis Mainly Based on Fasting Blood Glucose from Oral Glucose Tolerance Test

Gestational diabetes mellitus (GDM) is associated with poor pregnancy outcomes and increased long-term risk of metabolic diseases for both mother and child. In Tanzania, GDM prevalence increased from 0% in 1991 to 19.5% in 2016. Anaemia has been proposed to precipitate the pathogenesis of GDM. We aimed to examine the prevalence of GDM in a rural area of Tanzania with a high prevalence of anaemia a

Cardiovascular Disease, Diabetes Mellitus, and Hypertension in Lewy Body Disease: A Comparison with Other Dementia Disorders

Background: Research concerning the potential roles of cardiovascular disease (CaVD) and diabetes mellitus (DM) as risk factors for Lewy body disease (LBD) is limited. These disorders are, however, established risk factors for vascular dementia (VaD) and have been proposed as risk factors for Alzheimer’s disease (AD). Objective: The aim of this study was to investigate the prevalence of CaVD and D

Patient registries for home oxygen research and evaluation

Randomized clinical trials are the preferred study design to address key research questions about the benefits or harms of interventions. However, randomized trials of oxygen therapy are difficult to conduct and have limitations. The purpose of this article is to offer our view on the potential use of patient registries in the field of home oxygen in COPD as an alternative to randomized trials by

Temporal hierarchies with autocorrelation for load forecasting

We propose four different estimators that take into account the autocorrelation structure when reconciling forecasts in a temporal hierarchy. Combining forecasts from multiple temporal aggregation levels exploits information differences and mitigates model uncertainty, while reconciliation ensures a unified prediction that supports aligned decisions at different horizons. In previous studies, weig

Pricing Activities : Bridgeing the Performativity - Coordination Divide in Economic Sociology

A fundamental question for economic sociology is: how are prices set? In economic sociological theory, a price is generally conceptualized either in terms of the performative construction of economy (e.g. a market device), or in terms of co-ordinational effects of power relations between buyers and sellers (e.g. the effect of social structures and institutions). In this paper, I set out to show ho

In the evening, I don’t walk in the park”: Perceived design qualities, safety and neighbourhood walkability

Introduction. Walking as a means of transportation is central in sustainable urban design. Little focus has, however, been placed on the influence of micro-level environmental features, such as vegetation and street lighting, on perceived safety and walking.Method. This study applied a non-explicit approach to explore the impact of greenery and outdoor lighting on neighborhood walkability. Partici

Evaluating the contribution of forest ecosystem services to societal welfare through linking dynamic ecosystem modelling with economic valuation

Trade-offs exist among the multiple ecosystem services (ES) generated by forests. Generally, wood production conflicts with the provisioning of public-good ES such as the storage of carbon, nutrient retention and conservation of biodiversity. Recognizing that forests generate both private- and public-good ES implies that forestry should be optimized to maximize the contribution of forests to socie

Supply Chain Incentive Alignment: The Gap between Perceived Importance and Actual Practice

Incentive alignment is discussed as one of the key factors for successful implementation of supply chain management. However, there is a lack of empirical research regarding implementation as well as evaluation of the effects of alignment mechanisms in practice. The purpose of this study is therefore to explore and describe the current practice and to identify gaps of Supply chain incentive alignm

Interaction Between Type 2 Diabetes Prevention Strategies and Genetic Determinants of Coronary Artery Disease on Cardiometabolic Risk Factors

Coronary artery disease (CAD) is more frequent among individuals with dysglycemia. Preventive interventions for diabetes can improve cardiometabolic risk factors (CRFs), but it is unclear whether the benefits on CRFs are similar for individuals at different genetic risk for CAD. We built a 201-variant polygenic risk score (PRS) for CAD and tested for interaction with diabetes prevention strategies

Subject Float, Low Subject Trapping, and Case in Icelandic

This article describes and discusses two peculiar sets of (in)defi nitenessfacts applying to subjects in Icelandic, here referred to as Subject Floatand Low Subject Trapping. Indefi nite subjects (commonly quantifi ed) inpresentational sentences and related clause types may either occupy thecomplement position within the predicate phrase or “fl oat” into variouspositions in the middle fi eld. This

Defrosting and Frost Protection Measurements of Heat Recovery in Cold Climate

The installation of technical solutions for heat recovery from the ventilation air is a very important step, both with respect to improving the indoor climate and as an energy-saving measure. Ventilation without heat recovery use a substantial part of an entire building's heating use, especially if the building is a low energy building. To realize a large implementation of heat recovery property o

Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype

SUGCT (C7orf10) is a mitochondrial enzyme that synthesizes glutaryl-CoA from glutarate in tryptophan and lysine catabolism, but it has not been studied in vivo. Although mutations in Sugct lead to Glutaric Aciduria Type 3 disease in humans, patients remain largely asymptomatic despite high levels of glutarate in the urine. To study the disease mechanism, we generated SugctKO mice and uncovered imb

Contact allergy to citral and its constituents geranial and neral, coupled with reactions to the prehapten and prohapten geraniol

Background: Citral is commonly used as a fragrance and flavor material and consists of the aldehydes geranial and neral. Citral is included in fragrance mix (FM) II. Geranial and neral have also been identified in autoxidation of geraniol, a fragrance compound present in FM I. Objectives: To study contact allergy to citral, geranial, and neral, and concomitant reactivity to oxidized geraniol and f

Systematic microbial production of optically active dissolved organic matter in subarctic lake water

The ecology and biogeochemistry of lakes in the subarctic region are particularly sensitive to changes in the abundance and optical properties of dissolved organic matter (DOM). External input of colored DOM to these lakes is an extensively researched topic, but little is known about potential reciprocal feedbacks between the optical properties of DOM and internal microbial processes in the water.