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An experimental study to improve the design of brine discharge from desalination plants
Customer-based brand equity and human resource management image : Do retail customers really care about HRM and the employer brand?
Purpose: The purpose of this study is to investigate the relationship between an organization’s human resource management (HRM) image and its customer-based brand equity. Research into HRM in relation to branding has mostly dealt with how to attract and maintain employees through employer branding. The present study attempts to link HRM directly to marketing and branding aimed at customers as an a
Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure
Failure of the human heart to maintain sufficient output of blood for the demands of the body, heart failure, is a common condition with high mortality even with modern therapeutic alternatives. To identify molecular determinants of mortality in patients with new-onset heart failure, we performed a meta-analysis of genome-wide association studies and follow-up genotyping in independent populations
Antipsychotics - Postmortem fatal and non-fatal reference concentrations
Endarterectomy patients with elevated levels of circulating IL-16 have fewer cardiovascular events during follow-up
Background and purpose Increased interleukin 16 (IL-16) levels in carotid plaques have been associated with reduced incidence of cardiovascular (CV) events during follow-up in patients who underwent carotid endarterectomy (CEA). In the present study we aimed to determine whether high circulating levels of IL-16 also are associated with a decreased risk of CV events after CEA. Methods Patients, who
Increased expression of the diabetes gene SOX4 reduces insulin secretion by impaired fusion pore expansion
The transcription factor Sox4 has been proposed to underlie the increased type 2 diabetes risk linked to an intronic single nucleotide polymorphism in CDKAL1. In a mouse model expressing a mutant form of Sox4, glucose-induced insulin secretion is reduced by 40% despite normal intracellular Ca2+ signaling and depolarization-evoked exocytosis. This paradox is explained by a fourfold increase in kiss
The role of management accounting and control in making professional organizations horizontal
Purpose – In the last decade, greater attention has been paid to the role of management accounting and control (MAC) in making professional organizations more horizontal. The authors argue that earlier research has not shown how the interrelatedness between professional identities and MAC influences attempts to make organizations more horizontal. In this paper the authors respond to the call for m
Corticosteroids or Not for Postoperative Nausea : A Double-Blinded Randomized Study
Background: Postoperative nausea and vomiting (PONV) is common after general anaesthesia, and corticosteroids are used in many protocols for enhanced recovery after surgery (ERAS). However, surgical techniques are developing, and ERAS protocols need to be reevaluated from time to time. Patients and method: In this study, we compared the effects of oral vs. parenteral corticosteroid administration
Treatment with a GnRH receptor agonist, but not the GnRH receptor antagonist degarelix, induces atherosclerotic plaque instability in ApoE-/- mice
Androgen-deprivation therapy (ADT) for prostate cancer has been associated with increased risk for development of cardiovascular events and recent pooled analyses of randomized intervention trials suggest that this primarily is the case for patients with pre-existing cardiovascular disease treated with gonadotropin-releasing hormone receptor (GnRH-R) agonists. In the present study we investigated
Genetic risk factors for type 1 diabetes
Type 1 diabetes is diagnosed at the end of a prodrome of β-cell autoimmunity. The disease is most likely triggered at an early age by autoantibodies primarily directed against insulin or glutamic acid decarboxylase, or both, but rarely against islet antigen-2. After the initial appearance of one of these autoantibody biomarkers, a second, third, or fourth autoantibody against either islet antigen-
Errors in medication history at hospital admission : Prevalence and predicting factors
Beam line I411 at MAX II - Performance and first results
Word Learning in the Developing Brain : ERP Dynamics of Learning Word-Object Associations
This dissertation investigated electrophysiological measures of individual differences in toddlers’ ability to learn novel object labels and process familiar object words and their referents. The studies measured both visual and auditory event-related potentials (ERPs) in response to pictures of objects and words in a longitudinal sample of 20- to 24-month-olds, an age of dynamic vocabulary develo
Epigenetic and Transcriptional Alterations in Human Adipose Tissue of Polycystic Ovary Syndrome
Genetic and epigenetic factors may predispose women to polycystic ovary syndrome (PCOS), a common heritable disorder of unclear etiology. Here we investigated differences in genome-wide gene expression and DNA methylation in adipose tissue from 64 women with PCOS and 30 controls. In total, 1720 unique genes were differentially expressed (Q < 0.05). Six out of twenty selected genes with largest exp
Regulation of Islet Function by the Neuropeptide PACAP
It is known that parasympathetic, sympathetic and sensory nerves innervate the islets and that these nerves harbor both classical neurotransmitters and neuropeptides. However, the neural influence on islet hormone release is complex and not yet fully understood A recently discovered pancreatic neuropeptide is pituitary adenylate cyclase-activating polypeptide (PACAP). The aim of this thesis was to
Three-year outcome of rivastigmine treatment in Alzheimer's disease in a routine clinical setting.
Lost Worlds? : Heritage in a Cultural Economy
Discussions of the cultural economy often focus upon the movement of such things as signs, media images, fashion and their entanglement in economic processes, but less attention has been paid to the concrete ways in which cultural heritage is affected by the processes and conditions of commoditization. This paper focuses upon how two museums of Scandinavian heritage struggle with very different cu
Learning from accident investigations – A cross-country comparison
Past and Present Roles of Packages in Logistics and towards the Future
Throughout history packages are used to contain, store and transport goods and products. In early days it was a matter of gathering and storing locally, whereas in today’s global enterprises packaging is an important issue in the operational management in networks of functions and/or divisions, often separated geographically around the world. Packaging has become a part of the process of efficient