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Validation of a multi-marker model for the prediction of incident type 2 diabetes mellitus: Combined results of the Inter99 and Botnia studies.

Purpose: To assess performance of a biomarker-based score that predicts the five-year risk of diabetes (Diabetes Risk Score, DRS) in an independent cohort that included 15-year follow-up. Method: DRS was developed on the Inter99 cohort, and validated on the Botnia cohort. Performance was benchmarked against other risk-assessment tools comparing calibration, time to event analysis, and net reclassi

Young women choosing contraceptives : stories about information literacy practices related to evaluation and use of information sources

I artikeln presenteras delresultat från ett doktorand-projekt om informationskompetenspraktiker i svenskt vardagsliv: unga kvinnors (18-23 år) informations-kompetenspraktiker när de väljer preventivmedel. Syftet är att förstå de unga kvinnornas perspektiv som det kommer till uttryck i deras berättelser om val och värdering av informationskällor om preven-tivmedel.En metod inspirerad av narrativa i

The future of incretin-based therapy: novel avenues-novel targets.

Incretin-based therapy for type 2 diabetes is based on the antidiabetic effects of glucagon-like peptide-1 (GLP-1) and instituted by GLP-1 receptor agonists and dipeptidyl peptidase-4 inhibitors targeting the key islet defects of the disease. The treatment is clinically efficient and safe, and associated with a low risk of adverse events. It can be used both in early and late stages of the disease

Varför etiska kommittéer?

This thesis analyses the development of ethics committees from a sociology of law perspective and a social steerage perspective ("social control"). The main question is: Why are ethics committees established? Institutionalised ethics committee is a rather new phenomenon, which has become widely spread in the last 20 years. The study points out the public ethical debate since the 1980s as a major e

Recognizing Macroeconomic Fluctuations in Value Based Management

Value Based Management (VBM) has become a common tool for evaluating corporate strategies and projects from the perspective of shareholder value maximization, and can be an important input for corporate compensation systems. But traditional VBM frameworks make no systematic effort to distinguish between changes in performance attributable to macroeconomic fluctuations beyond management's control a