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Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids

The common patatin-like phospholipase domain-containing protein 3 (PNPLA3) variant I148M predisposes to nonalcoholic liver disease but not its metabolic sequelae. We compared the handling of labeled polyunsaturated fatty acids (PUFAs) and saturated fatty acids (SFA) in vivo in humans and in cells harboring different PNPLA3 genotypes. In 148M homozygous individuals, triglycerides (TGs) in very low-

Allergic contact dermatitis caused by isobornyl acrylate in the Enlite glucose sensor and the Paradigm MiniMed Quick-set insulin infusion set

Background: The FreeStyle Libre glucose sensor has caused many cases of allergic contact dermatitis, and isobornyl acrylate (IBOA) in this sensor has been identified as one of the culprit allergens. Objectives: To report on the presence of IBOA in devices produced by Medtronic, namely, Enlite sensor and insulin infusion set Paradigm MiniMed Quick-set. Patients and Methods: Five patients reacting t

Early probiotic supplementation and the risk of celiac disease in children at genetic risk

Probiotics are linked to positive regulatory effects on the immune system. The aim of the study was to examine the association between the exposure of probiotics via dietary supplements or via infant formula by the age of 1 year and the development of celiac disease autoimmunity (CDA) and celiac disease among a cohort of 6520 genetically susceptible children. Use of probiotics during the first yea

Recognizing Macroeconomic Fluctuations in Value Based Management

Value Based Management (VBM) has become a common tool for evaluating corporate strategies and projects from the perspective of shareholder value maximization, and can be an important input for corporate compensation systems. But traditional VBM frameworks make no systematic effort to distinguish between changes in performance attributable to macroeconomic fluctuations beyond management's control a

Urban Space and Everyday Adaptations : Rethinking commons, co-living, and activism for the Anthropocene City

This paper addresses Jem Bendell’s concept of “deep adaptation” in the Anthropocene through the lens of everyday urban practices in contemporary Northern Europe. It proposes that this “deep adaptation” should be defined less in relation to a socio-ecological “collapse” and more through everyday occurrences in present- day urban environments.Entering into a critical conversation with Bendell’s conc

Exploring the environmental impacts of olive packaging solutions for the European food market

Reduction of packaging waste has been a European target for more than 40 years. However, packaging is indispensable for protecting what it carries. In this study, an analysis of the European regulations on packaging and of their resulting effect on recycling performance was performed by means of a literature survey and the national results published in the European Database, Eurostat. Based on the

Comparison of two extraction methods for the determination of selective serotonin reuptake inhibitors in sewage sludge by hollow fiber liquid-phase microextraction

This paper presents two procedures for the determination of four selective serotonin reuptake inhibitors (citalopram, paroxetine, fluoxetine, and sertraline) and one metabolite (norfluoxetine) in sewage sludge utilizing three-phase hollow fiber liquid-phase microextraction (HF-LPME). First, direct HF-LPME was used for extraction, clean-up, and preconcentration. The pharmaceuticals were extracted f

“Hur det påverkar mig som medarbetare är kärnan i det hela” - En kvalitativ studie om hur personal på en skatte- och revisionsbyrå upplever organisatoriska förändringar

Syftet med denna studie var att undersöka hur anställda på en skatte- och revisionsbyrå upplever organisatoriska förändringar samt hur organisationens kommunikation kan påverka dessa upplevelser och tilliten till organisationen. Studien genomfördes som en kvalitativ intervjustudie med semistrukturerade intervjuer med nio anställda i olika roller på en skatte- och revisionsbyrå i Sverige. Urvalet v

Framtidsångest bland universitetsstudenter i sverige: En kvantitativ studie

Framtidsångest är bland studenter ett bestående samt växande problem som har en betydande påverkan på dels den mentala hälsan men även den akademiska framgången. Hur den hanteras och motverkas skiljer sig således beroende på olika faktorer, denna studie kommer att belysa vilken roll self-efficacy, locus of control (intern/extern) och problem- samt emotionsfokuserad coping spelar i detta. Metoden sFuture anxiety is an existing and continuous issue that has a significant impact on the mental health and academic success among university students. How it is handled and counteracted thus differs depending on various factors such as self-efficacy, locus of control (internal/external), emotion focused and problem focused coping, which are highlighted in this study. The method used to investigate

"Den här gången är det en fyrhjuling": En sociomateriell studie av migreringsprocessen till ett nytt bibliotekssystem

This thesis explores the sociomaterial dynamics involved in the migration process to a new library system, specifically focusing on the case of Quria, developed by Axiell and launched in 2017. Using a sociomaterial perspective the study examines how this technological transition affects the social structures within library organizations. The research is based on qualitative data collected through

Undersökning av inomhusmiljön i bostadshus i Kurdistan med förslag på förbättringar

Undersökning av inomhusmiljön i Bostadshus i Kurdistan med förslag på förbättringar Av Zahir Rashid Ibrahim Sammanfattning Den varma sommarsäsongen i Kurdistan är mycket lång och omgivningstemperaturen är cirka 45 ˚C. Byggnader kyls ner med luftkonditioneringssystem på sommaren och värms upp med eldrivna eller oljedrivna värmesystem på vintern. Oljedrivna placeras oftast i vardagsrummet Examination of indoor environment in dwellings in Kurdistan with suggestions on improvements By Zahir Rashid Ibrahim Summary The hot summer season in Kurdistan is very long and the ambient temperature is about 45 ˚C. Buildings are cooled by air conditioning systems in the summer and heated with electric or oil-fired heating systems in winter. Oil-driven are usually placed in the living roo