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When restoring former agricultural land to more low-nutrient input ecosystems, the establishment of a plant community can be enhanced by sowing desirable species. In this study our aim was to determine whether management of the plant community influences the microarthropod community. We carried out a field experiment in three European countries on set-aside arable land and determined soil mites fr

BACKGROUND. Prostate specific antigen (PSA) is widely used for prostate cancer screening but its levels are influenced by many non cancer-related factors. The goal of the study is to estimate the effect of genetic variants on PSA levels. METHODS. We evaluated the association of SNPs that were reported to be associated with prostate cancer risk in recent genome-wide association studies with plasma

Background: Local pain at the site of intravenous (iv) injection of propofol remains a considerable problem in clinical anaesthesiology, and particularly so in infants. The aim of the present study was to compare the influence of two different emulsions of propofol on local pain following iv administration. Methods: Eighty adult patients (ASA I-II) scheduled for ear-nose-throat or plastic surgery

The general aim of this thesis was to characterize hematologic malignancies using gene expression profiling in order to obtain an improved classification and to study deregulated transcriptional networks in leukemia. In the first study (Article I), the gene expression profiles of hematologic cell lines were analyzed to investigate whether such cell lines maintain expression profiles that are chara

Background: Patients with rheumatoid arthritis ( RA) are at increased risk of malignant lymphomas, and maybe also of leukaemia and multiple myeloma. The effect of tumour necrosis factor (TNF) antagonists on lymphoma risk and characteristics is unclear. Objective: To assess expected rates and relative risks of haematopoietic malignancies, especially those associated with TNF antagonists, in large p

Median micturition volume decreased early after partial outlet obstruction, 24 hrs total obstruction and hemidenervation. Degeneration release of transmitter may explain this, assuming that bladder wall distension causes nerve degeneration. Micturition pressure decreased simultaneously in the partially denervated and 24 hrs obstructed groups, probably due to the reduced number of functionally inta

The aim was to study the epidemiology of chronic pain (> 3 months duration) and factors associated to pain prevalence, prognosis, health care and medication in a general population. A cross-sectional mailed survey to a random population sample (n = 1806) was followed by a clinical examination and a prospective study of three selected groups. Pain related diagnoses from primary health care was moni

Almost all northern forest tree species live in symbioses with ectomycorrhizal fungi (EMF). The trees allocate up to half of the photoassimilated carbon (C) through the roots to EMF. In return EMF deliver nutrients from both inorganic and organic sources in the soil, as well as water. Most of the nutrients trees need are assimilated through EMF, which thus play a potentially important role in reta

Body dimensions of 2,936 newborns with cleft lip/palate (CLP) were compared with 2,031,140 singleton newborns between 1973 to 1992. The risk of cleft development was found to be associated with intra-uterine growth retardation - the more severe the cleft, the stronger the association. As digital photography is being increasingly applied in clinical medicine, we devised a computer software program

Calcium homeostasis involves mainly the interaction of PTH, vitamin D and CT. The stomach may be important for calcium homeostasis. Gastric acid is thought to mobilize calcium from the diet, thereby facilitating the absorption of calcium in the small intestines. In the rat, gastrectomy rapidly reduces the calcium content, the density and the trabecular volume of the bone. The gastrectomy-evoked bo

Brain ischemia is a major cause of death and morbidity in the industrialized countries. It is mainly caused by stroke, but may also be the consequence of successful cardiopulmonary resuscitation in victims of cardiac arrest, known as transient global ischemia. Although extensive effort in the field of brain research using experimental rodent models, no neuroprotective treatments are at present ava

There is little knowledge about the circulatory effects of dopamine in hypothermia. Induced hypothermia has been shown to improve outcome in various settings. Hypothermia is also used for preservation of organs that are harvested for transplantation. We evaluated lungs that were topically cooled for 6 hours in non-heart-beating donor pigs by transplanting them into recipient pigs and observing the