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Uppsatsen syftar till att undersöka vad som för svensk rätts del kan sägas gälla förandet och värderingen av förundersökningstystnad som bevis för att den tilltalade begått den gärning som omfattas av åklagarens gärningsbeskrivning. Med ”förundersökningstystnad” avses här den tilltalades tystnad i förhör under förundersökningen, som därefter efterföljs av utsaga vid huvudförhandlingen. Arbetet m

The large protein family called G Protein-coupled receptors (GPCRs) has co-evolved with life throughout evolution; from single cell organisms all the way to complex beings such as us humans. The fact that GPCRs are involved in essentially every physiological event, and that ~50% of drugs on the current market are either directly or indirectly targeted towards the function of GPCRs, we can be certa

This thesis is motivated by an increasing degree of unfamiliarity and prominence of national dimensions in multinational crisis management. The research rationale rests on the argument that trust is important but may erode when roles conflict, which in turn may result when stakeholder interests diverge. The thesis describes trust and national perspectives in terms of role conflict in an EU Operati

Neutrophils are our most numerous and deadly white blood cells and without them we would succumb quickly to infections by pathogens. The main mechanism that the neutrophils employ for our protection is phagocytosis, where they eat and enclose their target inside a membrane-bound organelle, the phagosome. Neutrophil phagosomes are highly dynamic entities, and a large amount of antimicrobial substan

Small cell lung carcinoma (SCLC) is a very aggressive solid tumor and is often widely metastasized by the time of diagnosis. Despite good response to the initial chemotherapy, SCLC cells often develop multidrug resistance to conventionally used chemotherapeutic drugs, which cause almost all SCLC tumors to relapse. The 5-year survival rate for patients with limited disease is around 20% while it is

Cardiovascular complications are frequent in type 2 diabetes (T2D) and cardiovascular death is the most common cause of death for these individuals. A region on chromosome 19 (19q13) has been indicated by several genome scans as a susceptibility locus for T2D or components of the metabolic syndrome (MetS). This gene rich region contains the gene encoding muscle glycogen synthase (GYS1), earlier as

Celiac disease is a prevalent small bowel disease in children caused by permanent intolerance against gliadin, which is the alcohol-soluble fraction of the cereal protein gluten in wheat, rye and barley. Celiac disease is characterized by an inflammatory infiltrate of CD4+ T lymphocytes in the intestinal mucosa leading to damage of villous structure and loss of absorptive surface. As a consequence

Risk stratification of patients with chronic kidney disease and atherosclerotic heart disease is crucial. Microalbuminuria (MA) is associated with an increased risk of kidney and cardiovascular (CV) death, especially in patients with diabetes. However, MA in many instances is not sensitive for disease outcome; for instance, not all diabetic patients with albuminuria progress to kidney failure, and

Gastrointestinal dysmotility is common, particularly in patients with diabetes mellitus. The aim of this thesis is to explore whether gastrointestinal dysmotility and endocrine secretion are interrelated, and how the symptoms manifest themselves in these patients. Patients with diabetes mellitus and gastrointestinal symptoms underwent gastric emptying scintigraphy, esophageal manometry and deep-

Seminal plasma is semen without the spermatozoa. Human seminal plasma is a complex mixture of secretions from the sex accessory glands, mainly the seminal vesicles and the prostate. Seminal plasma has high protein content and it also contains ions, sugars and low molecular weight components. Immediately after ejaculation the semenogelins and fibronectin aggregate and a coagulum forms trapping the

Connective tissue contains a prominent extracellular matrix (ECM), which provides for physiological and mechanical properties. Intra- and inter-molecular interactions between proteins in this ECM provide for the formation of molecular networks. These interactions determine the shape of the tissue as well as cell behavior. This thesis is focused on the leucine-rich repeat proteoglycans fibromodulin

Posterior laryngitis (PL) is defined as an inflammation involving the posterior part of the glottal region in conjunction with symptoms. The cause is multifactorial. The aims of the work presented in this thesis were to examine symptoms, physical signs, different aetiologies and health-related quality of life (HRQOL) in patients with PL and/or oesophageal dysmotility. In paper I, a group of pati

Sammanfattning Idag ökar mängden information hela tiden. Mycket av informationen finns bara i elektronisk form och därför har elektronisk bevisning blivit allt vikti-gare. E-post är en form av elektronisk bevisning som har blivit ett alltmer betydelsefullt kommunikationsmedel och är en viktig del av såväl privat- som affärsliv. Det utgör ett snabbt och lättillgängligt kommunikationssätt som på månThe amount of information is constantly increasing, much of which is only available in electronic form. Therefore the role of electronic evidence has become increasingly important. One form of such electronic evidence is e-mail, which has become an important part of both private and business life, due to the importance of quick and accessible means of communication. E-mail communication differs fr

Inom konkursrätten syftar bouppteckningseden till att förmå gäldenären att uppge alla tillgångar i konkursboet sanningsenligt. Uppsatsen behandlar bouppteckningsedens uppkomst ur ett rättshistoriskt perspektiv med det bakomliggande motivet att fastställa dess syfte och religiösa prägel. Vidare behandlas frågan vilken ställning bouppteckningen har i dagens konkursrätt och hur pass nödvändig den är Under bankruptcy law the estate inventory-oath aims to persuade the debtor to disclose all the assets of the bankruptcy estate truthfully. This essay deals with the origin of oath from a legal historical perspective, with of aim of defining its purpose. It further examines the status of the estate inventory-oath in the current bankruptcy law and how necessary it is in practice. A study of legal

Denna uppsats undersöker hur de svenska vägarna kommer att påverkas om klimatscenariona slår in och hur klimatförändringarna påverkar vägarnas sårbarhet. Uppsatsen svarar på frågorna om vilka klimatfaktorer som påverkar vägarna, hur vägbyggen ska anpassas till klimatförändringarna samt hur man kan förebygga skador på de befintliga vägarna som orsakas av klimatförändringarna.

Sammanfattning Uppsatsen behandlar det adopterade barnets rätt till kännedom om sitt ursprung. Frågan har diskuterats vid flertalet tillfällen och är nu aktuell på nytt, då den uppmärksammas i utredningen SOU 2009:61 – Modernare adoptionsregler. I utredningen föreslås en lagstadgad informationsskyldighet för adoptivföräldrar att informera barnet om dess ursprung. Denna bestämmelse skall sakna sankSummary This Graduate Thesis examines the adopted child´s right to knowledge of his or her origin. The biological parentage has been a subject of discussion throughout the history of adoption. In accordance with SOU 2009:61, the Committee has proposed a provision to be introduced requiring a person who has an adopted child, to inform the child of his or her biological origin. The provision is not

Den här uppsatsen handlar om förhållandet mellan senmedeltida och tidigmodernt fursteideal. Studien är en komparativ idéanalys mellan den svenska "Konungastyrelsen" och Machiavellis "Fursten". Genom att anlägga politisk kultur som analytiskt redskap visar jag att det finns en idéhistorisk kontinuitet, med vissa brott och förändringar, i det västeuropeiska fursteidealet.