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Identification of infants with increased type 1 diabetes genetic risk for enrollment into Primary Prevention Trials—GPPAD-02 study design and first results

Primary prevention of type 1 diabetes (T1D) requires intervention in genetically at-risk infants. The Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) has established a screening program, GPPAD-02, that identifies infants with a genetic high risk of T1D, enrolls these into primary prevention trials, and follows the children for beta-cell autoantibodies and diabetes. Genetic testin

Emerging Welfare States: Comparing East Asian and Scandinavian Redistribution Models in a Global Context

In this paper we discuss social policy in relation to different development contexts, where characteristics and outcomes of social policies in different sectors ( e.g.,housing, care, education, social security) are compared. The paper relates to the discussion on the causes and outcomes of welfare state management in different contexts. However, existing analytical models do not fit the mixtures

Circulating Human Basophils and Dendritic Cell Subsets. Aspects of antigen recognition and presentation in type I allergic immune responses

Allergic diseases currently affect a third of the population in the industrialized parts of the world. Despite this, the cellular and molecular mechanisms involved in the induction and activation of allergic diseases are not fully clarified. Dendritic cells (DCs) link the innate and adaptive immunity and play vital roles in protective immunity against pathogens, as well as in inducing tolerance t

Recognition of out-of-hospital cardiac arrest by medical dispatchers in emergency medical dispatch centres in two countries

Introduction Survival after out-of-hospital cardiac arrest (OHCA) remains low. Early recognition by emergency medical dispatchers is essential for an effective chain of actions, leading to early cardiopulmonary resuscitation, use of an automated external defibrillator and rapid dispatching of the emergency medical services. Aim To analyse and compare the accuracy of OHCA recognition by medical dis

Early–Middle Ordovician biotic and sedimentary dynamics in the Baltoscandian paleobasin

Baltoskandien utgör en del av paleokontinenten Baltica, vilken mestadels var täckt av ett grunt epeiriskt hav under den ordoviciska tidsperioden (ca 485,5–444 Ma). Detta uråldriga hav efterlämnade en tunn lagerföljd av sedimentära bergarter. Under tidig–mellanordovicium (ca 485,5–457,5 Ma) befann sig Baltica vid tempererade breddgrader på södra halvklotet och kallvattenkarbonater bildades över stoThe Baltoscandian region forms part of the paleocontinent Baltica, which was largely covered by a shallow epeiric sea throughout much of the Ordovician (c. 485.5–444 Ma). This ancient sea is today recorded by a thin succession of sedimentary rocks. During the Early–Middle Ordovician (c. 485.5–457.5 Ma), Baltica was situated in mid-latitudes on the southern hemisphere and cool-water carbonates form

Test–Retest Reliability, Agreement and Criterion Validity of Three Questionnaires for the Assessment of Physical Activity and Sedentary Time in Patients with Myocardial Infarction

Regular physical activity (PA) and limited sedentary time (SED) are highly recommended in international guidelines for patients after a myocardial infarction (MI). Data on PA and SED are often self-reported in clinical practice and, hence, reliable and valid questionnaires are crucial. This study aimed to assess the test–retest reliability, criterion validity and agreement of two PA and one SED qu

Long-term linguistic outcome in adults with congenital cytomegalovirus infection

BACKGROUND: Congenital cytomegalovirus (cCMV) is the most common prenatal infection and the main infectious cause of neurodevelopmental abnormalities in developed countries. Long-term neuropsychological outcome of cCMV infection is still not well understood. This is the first study that presents linguistic follow-up data performed on adults who were infected in utero.METHOD: All individuals from a

How Pippi came to the German Democratic Republic

The first edition of Astrid Lindgren's book Pippi Langstrumpf (GDR/1975) is our starting point for this presentation. It is also our first joint presentation of our project “Pippi beyond the border” (The Foundation for Baltic and East European Studies). The aim of the project is to examine the complex reception history of Astrid Lindgren's classic children's book Pippi Longstocking in the GDR, whi