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Towards Generation of Human Hematopoietic Stem Cells from Pluripotent Stem Cells.

There is a pressing need for compatible Hematopoietic Stem Cells (HSCs), in high quantities and of good clinical quality, to ensure optimal treatment for patients with various blood malignancies. Pluripotent Stem Cells (PSCs) have the potential to be a source for generating HSCs. The indefinite expansion capacity of PSCs, combined with the possibility of creating these cells from patient-specific

Symptom occurrence and distress after heart transplantation—a nationwide cross-sectional cohort study

Experiencing symptoms after heart transplantation may hamper the heart recipient’s self-management which can lead to negative effects. We know little about symptom occurrence and distress after heart transplantation, especially in relation to sociodemographic variables. The aim of the study was to explore self-reported symptom occurrence and distress after heart transplantation and their relations

Islamiska regimen i Iran hetsar mot Sverige

Regimen i Iran missbrukar diplomatisk infrastruktur i operationer som underminerar internationell säkerhet. Sverige bör noggrant övervaka aktiviteterna vid Irans ambassad på Lidingö och överväga att stänga den helt och hållet. Det skriver Arvin Khoshnood, Irankännare och statsvetare samt Ardavan Khoshnood, docent Lunds universitet.

The Role of Scientific Language Use and Achievement Level in Student Sensemaking

Many science students struggle with using scientific language and making sense of scientific phenomena. Thus, there is an increased interest in science education research and public policy with regard to understanding and promoting scientific language use and sensemaking in science classrooms. However, there is a lack of comparative studies on how upper-secondary school students of different achie

Development of a risk score for scoliosis in children with cerebral palsy

Background and purpose — Children and young adults with cerebral palsy (CP) have an increased risk of developing scoliosis, with a prevalence ranging from 11% to 29%. Information on risk factors for the emergence and progression of scoliosis is inconclusive. This study aimed to develop a risk score based on 5-year-old children with CP to predict the risk of scoliosis before the age of 16. Patients

Biological wound matrices with native dermis-like collagen efficiently modulate protease activity

Objective: When the delicate balance between catabolic and anabolic processes is disturbed for any reason, the healing process can stall, resulting in chronic wounds. In chronic wound pathophysiology, proteolytic imbalance is implicated due to elevated protease levels mediating tissue damage. Hence, it is important to design appropriate wound treatments able to control and modulate protease activi

Scandinavian Multicenter Acute Subdural Hematoma (SMASH): Study Protocol for a Multinational Population-Based Consecutive Cohort

BACKGROUND: Traumatic acute subdural hematomas (ASDHs) are associated with high rate of morbidity and mortality, especially in elderly individuals. However, recent reports indicate that the morbidity and mortality rates might have improved.OBJECTIVE: To evaluate postoperative (30-d) mortality in younger vs elderly (≥70 yr) patients with ASDH. Comparing younger and elderly patients, the secondary o