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Cone-rod degeneration (CRD) belongs to the disease spectrum of retinal degenerations, a group of hereditary disorders characterized by an extreme clinical and genetic heterogeneity. It mainly differentiates from other retinal dystrophies, and in particular from the more frequent disease retinitis pigmentosa, because cone photoreceptors degenerate at a higher rate than rod photoreceptors, causing s

High quality of warfarin treatment is important to prevent recurrence of venous thromboembolism (VTE) without bleeding complications. The aim of this study was to examine the effect of individual time in therapeutic range (iTTR) and International Normalised Ratio (INR) variability on bleeding risk and mortality in a large cohort of wellmanaged patients with warfarin due to VTE. A cohort of 16612 p

This study investigates the effects of Age of Onset of Acquisition (AOA) and the quality and quantity of input on the longitudinal development of gender in the acquisition of French by simultaneous (2L1) and successive bilingual children (cL2). There's an on-going debate regarding the main factors underlying linguistic development in bilingual children. Two independent variables, AOA and input, ha

Global teaching and learning for sustainable development reaches from the classroom to the world outside, and is therefore a particularly interesting setting for practising transition skills. The article suggests a number of features perceived as crucial in developing young people's capability to act in a changing world and under circumstances that are difficult to predict. The suggestions are bas

Background: Housing environments that hinder performance of daily activities and impede participation in social life have negative health consequences particularly for the older segment of the population. From a public health perspective accessible housing that supports active and healthy ageing is therefore crucial. The objective of the present study was to make an inventory of environmental barr

Background: Lymphedema may affect patients' health-related quality of life (HRQoL) and thus a disease-specific questionnaire is needed. The Lymphedema Quality of life Inventory (LyQLI) has been tested for reliability and validity. The purpose of this study was to test the LyQLI for responsiveness and sensitivity. Methods and Results: The study participants were patients with lymphedema in the uppe

The objective in this research has been to predict the current and future moisture and temperature distribution in a concrete reactor containment, RC. The overall objective in this project was to create a model to be able to predict the moisture and temperature distribution in the concrete wall of the RC of a Pressurized Water Reactor, PWR. In addition, one objective was to design a model to simul

BACKGROUND: Women with a history of hypertensive disorders of pregnancy (HDP) are at increased risk of hypertension, cardiovascular disease, and type 2 diabetes. Offspring from pregnancies complicated by HDP also have worse cardiometabolic status in childhood and young adulthood, but the offspring risk of clinical hypertension in adulthood is largely unknown.METHODS: We studied 13,893 first-born a

This paper focuses on the writer’s doctoral research about the development of a 3D digital approach to study, analyse and (re)interpret archaeological collections. 3D documentation, based on the integration of digital technologies, is applied to a group of small terracotta figurines from the Ayia Irini archaeological excavation (Cyprus).The aim of the research is to enhance the stylistic, typologi