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Bleeding complications in venous thrombosis patients on well-managed warfarin.

Anticoagulation treatment is effective in preventing both death and recurrence in patients with venous thromboembolism (VTE), but at the same time confers a substantial risk of bleeding complications. The aim of this study was to examine the rate of and predictors for bleeding complications in VTE patients on warfarin with high treatment quality. In total 13,859 patients on warfarin for VTE betwee

Clinical Indications, Utilization, and Funding of Bariatric Surgery in Europe

The objective of this study was to evaluate the current utilization, the level of endorsement by professional societies, and health technology assessment bodies, as well as the reimbursement levels for bariatric surgery in European countries. We performed an analysis of the indications for bariatric surgery based on national clinical and commissioning guidelines, current utilization of surgery, ch

Population structure and migratory directions of Scandinavian bluethroats (Luscinia svecica) -a molecular, morphological and stable isotope analysis

Abstract in UndeterminedMany species of birds show evidence of secondary contact zones and subspeciation in their Scandinavian distribution range, presumably resulting from different post-glacial recolonization routes. We investigated whether this is the case also in the Scandinavian bluethroat Luscinia svecica, a species that has been suggested to consist of two separate populations: one SW-migra

Prevalence and genetics of immotile-cilia syndrome and left-handedness

Immotile-cilia syndrome is characterized by severe respiratory distress from early infancy, and also often by situs inversus. The first description of the disease was based on just four persons, but reasons were given to suggest that the disorder may not be exceedingly rare. The purpose of the present study was to estimate just how rare or how common it is and to evaluate its association with situ

Methods for individualising factor VIII dosing in prophylaxis

Haemophilia A is a sex-linked disorder characterised chiefly by recurrent, spontaneous joint and muscle bleedings resulting from deficiency of factor VIII (FVIII). Recurrent joint bleeds result in haemophilic arthropathy. Unless treated with factor replacement therapy, many patients with severe haemophilia become disabled. The first clinical evidence favouring prophylaxis originated from the studi

Evaluation of prestress losses in nuclear reactor containments

The most critical safety barrier in a nuclear power plant, the concrete containment, is prestressed by hundreds of tendons, both horizontally and vertically. The main purpose of the containment is to prevent radioactive discharge to the environment in the case of a serious internal accident. Due to creep and shrinkage of concrete and relaxation of the prestressing steel, tendon forces decrease wit