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Diagnostic work-up of contralateral breast cancers has not improved over calendar period

Women who have been treated for breast cancer are typically followed up with regular mammography and palpation, with the aim of detecting recurrences and contralateral breast cancer (CBC). This study aims to investigate if the diagnostic work-up of breast cancer patients has improved over the last 25 years and resulted in earlier diagnoses of CBC. Two population-based cohorts were used; all CBCs i

The role of women's attitudinal profiles in satisfaction with the quality of their antenatal and intrapartum care

Objective: To compare perceptions of antenatal and intrapartum care in women categorized into three profiles based on attitudes and fear. Design: Prospective longitudinal cohort study using self-report questionnaires. Profiles were constructed from responses to the Birth Attitudes Profile Scale and the Fear of Birth Scale at pregnancy weeks 18 to 20. Perception of the quality of care was measured

The combined effect of wetting ability and durability on outdoor performance of wood : development and verification of a new prediction approach

Comprehensive approaches to predict performance of wood products are requested by international standards, and the first attempts have been made in the frame of European research projects. However, there is still an imminent need for a methodology to implement the durability and moisture performance of wood in an engineering design method and performance classification system. The aim of this stud

Environmental factors in the etiology of type 1 diabetes, celiac disease, and narcolepsy

The etiology of human leukocyte antigen (HLA)-associated organ-specific autoimmune diseases is incomplete. In type 1 diabetes and celiac disease, the strongest associations are with the HLA-DR3-DQ2 and DR4-DQ8 haplotypes, whereas the DQB1*06:02 allele has a strong negative association. In contrast, narcolepsy, especially as recently triggered by the Pandemrix® H1N1 vaccine (GlaxoKlineSmith (GSK),

Heritagelore : Museums and the manner in which Heritage might be understood in a trialectic framework of place, materiality and mobility

Historian David Lowenthal (1985) has pointed out the past is often perceived and represented as “a foreign country” in which cultural heritage is implicitly understood to be bound to geographical territories and associated notions of what it implies to have roots, an identity, and a place in which to belong. This is the paradigmatic background against which so many heritage museums have been found

THOC5 : A novel gene involved in HDL-cholesterol metabolism

Although numerous genes are known to regulate serum lipid traits, identified variants explain only a small proportion of the expected heritability. We intended to identify further genetic variants associated with lipid phenotypes in a self-contained population of Sorbs in Germany. We performed a genome-wide association study (GWAS) on LDL-cholesterol, HDL-cholesterol (HDL-C), and triglyceride (TG)