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Routine versus selective intraoperative cholangiography during cholecystectomy : systematic review, meta-analysis and health economic model analysis of iatrogenic bile duct injury

BACKGROUND: Bile duct injury (BDI) is a severe complication following cholecystectomy. Early recognition and treatment of BDI has been shown to reduce costs and improve patients' quality of life. The aim of this study was to assess the effect and cost-effectiveness of routine versus selective intraoperative cholangiography (IOC) in cholecystectomy. METHODS: A systematic review and meta-analysis, c

Untangling fracture risk in monoclonal gammopathy of undetermined significance : A population-based cohort study

Objective: Monoclonal gammopathy of undetermined significance (MGUS) is the asymptomatic precursor of multiple myeloma (MM). Lytic bone lesions and fractures are hallmarks of MM and although there are no lytic lesions in MGUS, it has also been associated with fractures. The causes of fractures in MGUS are currently unclear but potential causes include inherent MGUS bone disease, undiagnosed MM, an

Exploring the masculinization of innovation practice within a municipality

Purpose: The purpose of this study is to generate an empirically informed theoretical framework which can be used to analyze the relationship between gender and innovation in the context of a municipality. The authors present and analyze three illustrative tales from a feminist perspective. The authors thus offer a more balanced approach to the conceptualization of gendered ascriptions with respec

Genetic factors affect the susceptibility to bacterial infections in diabetes

Diabetes increases the risk of bacterial infections. We investigated whether common genetic variants associate with infection susceptibility in Finnish diabetic individuals. We performed genome-wide association studies and pathway analysis for bacterial infection frequency in Finnish adult diabetic individuals (FinnDiane Study; N = 5092, Diabetes Registry Vaasa; N = 4247) using national register d

Sociological imagination and our uncertain future

C.W. Mills suggests that having sociological imagination entails having ability to both distinguish between and connect personal troubles and public issues. This has been a guiding principle for much sociology in the last fifty years, but is never simple and continues to challenge the discipline. Especially the increasing number of sociologists engaging in endeavours to explain, understand, and im

Prevalence of skin disease in a population-based sample of adults from five European countries

Background: There is a lack of prevalence data on skin diseases in the general adult population; most studies have been carried out in small, national or consecutive clinical samples. Objectives: To determine the prevalence of common skin disease in the general European population and to assess differences in the characteristics of treatment between countries. Methods: A random sample consisting o

Experimenting with experiments 2.0: using mixed methods to learn about information search behavior

This presentation discusses an ongoing research project that aims to collect data about the practice of information search. It seeks to learn more about different ways in which tourist information is collected at different stages of a journey. Speaking to tourism planners and reading tourism research, it seems as if the digitalization of information has completely changed tourists’ information sea

Acoustically robust light weight constructions require controlled building process

Acoustically robust light weight constructions in multifamily houses require that the building processes are taken into account, i.e. it is necessary to describe in detail how to erect the house on site in order to fulfill the final result. Performance of details necessary for stability reasons, connections in joints, fixing of final strips etc have to be described clearly in order to achieve the

Inter-departmental variation in surgical treatment of proximal femoral fractures : A nationwide observational cohort study

Background and purpose Hip fractures should be treated based on the best available evidence and cost-effectively to optimize the outcome for this large group of frail patients. This study examined nationwide variation in surgical methods used for hip fractures. Methods In this cohort study 46,243 patients ≥65 years with a trochanteric hip fracture (THF) or a femoral neck fracture (FNF) registered