Alcohol and gene expression in nerve cells with emphasis on transcription factor AP-1
Alcohol induces profound effects on the function of the nerve cells in the nervous system. Alterations in gene expression is an important way by which these effects could be induced and sustained. Activating Protein-1 (AP-1) is a dimeric transcription factor constituted of proteins from the fos and jun immediate-early gene families. AP-1 induces gene expression of genes having a functional AP-1 bi