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Surface Modification of Biomedical Polyurethanes

The aim of the this thesis was surface modification of a biomedical polyurethane (PUR), Pellethane 2363-80AE*, to improve the biocompatibility. Surfaces modified by poly(ethylene oxide) (PEO) were prepared either by grafting PEO covalently at the PUR surface by a two-step reaction, or by using amphiphilic polymers containing PEO as the hydrophilic part. The amphiphilic polymers consisted of one co

Inducible nitric oxide synthase in experimental urinary tract infection

Urinary tract infection (UTI) is among the most common bacterial infections in humans and the majority are caused by Escherichia coli (E. coli). Abundant evidence indicates that nitric oxide (NO) produced by the inducible NO synthase (iNOS) plays an important role in host defense against infection. This thesis examines iNOS expression in experimental UTI models. The rat and pig bladder urothelium

Ventifacts and wind deflation surfaces in context with glaciofluvial sediment successions in southern Sweden – their age and implication for glacial history

Recent suggestions propose that the glacial landscape in southern Sweden is primarily a relict from the Saalian glaciation (>130 ka). The arguments for this standpoint are the assertion that the majority of glaciofluvial deposits in this region are till-covered, and that wind-abraded clasts are observed at the contact between glaciofluvial sediments and till at numerous locations. Furthermore, it

The Pneumatic Hybrid Vehicle - A New Concept for Fuel Consumption Reduction

Urban traffic involves frequent acceleration and deceleration. During deceleration, the energy previously used to accelerate the vehicle is mainly wasted on heat generated by the friction brakes. If this energy that is wasted in traditional internal combustion engines (ICE) could be saved, the fuel economy would improve. Today there are several solutions to meet the demand for better fuel economy

Community mobilization and peer education in a HIV-STI prevention program for university students

Slowing the incidence of HIV and STI among young people requires that they change their sexual behaviours. There is evidence that community-based interventions that target multiple levels of influence can be effective. In community mobilization different segments and sectors of a population are directly involved in problem identification and in the design and implementation of programs. The proces

Plant Major Intrinsic Proteins - natural variation and evolution

Major Intrinsic Proteins (MIPs, also called Aquaporins, AQPs) are channel forming membrane proteins. Although initially functionally characterized and named after their water channeling property in human red blood cells, it has become increasingly evident that MIPs are present in all types of organisms and transport a variety of small, uncharged molecules besides water. MIPs have a highly conserve

Algorithmic Improvements for Stochastic Rasterization & Depth Buffering

The field of computer graphics refers to the use of computers to generate realistic-looking images from virtual scenes. Graphics processing units use an algorithm known as rasterization to compute images of scenes viewed from a virtual camera. The commonly used pinhole camera model does not account for the imperfections that stem from the physical limitations in real-world cameras. This includes,

Merging Parton Showers and Matrix Elements

This thesis considers models for describing high energy particle collisions. Existing phenomonological models are modified and new implementations made in order to achive a better description of states with several hard jets. To predict final state hadrons, parton showers are used together with pheonomenological hadronization models. These models describe a wide range of observables, but have the

Event Detection in Eye-Tracking Data for Use in Applications with Dynamic Stimuli

This doctoral thesis has signal processing of eye-tracking data as its main theme. An eye-tracker is a tool used for estimation of the point where one is looking. Automatic algorithms for classification of different types of eye movements, so called events, form the basis for relating the eye-tracking data to cognitive processes during, e.g., reading a text or watching a movie. The problems with t

Ion channels and electrical activity in vascular smooth muscle: Effects of calcium store depletion, cholesterol and cholesterol-lowering drugs.

Smooth muscle cells (SMCs) in the vessel wall contract to regulate blood flow and pressure, a function essential for normal circulation through tissues. On the other hand, migration and proliferation of SMCs are important factors in vascular disease, such as atherosclerosis and restenosis following surgical dilatation. The conversion of the SMC to this role is marked by a modulation from contracti

Ribosomes and subunits from Escherichia coli studied by asymmetrical flow field-flow fractionation

In this thesis asymmetrical flow field-flow fractionation (FFF) separations of ribosomes and subunits have been studied. Ribosomal material was prepared from Escherichia coli (E. coli) cells and analyzed by the size separation technique. The five main peaks in the fractograms correspond to transfer RNA (tRNA), unidentified proteins, small subunit, large subunit, and ribosome. The accuracy of the

Artifacts and Supraphysical Worlds : A Conceptual Analysis of Religion

It is a contested question in contemporary theories of religion whether the concept of religion can be defined in a sound way or not. Many theorists maintain that a universal but delimiting definition is impossible. In this study, by contrast, it is argued that a conceptual analysis of religion that holds universally is perfectly possible because the following thesis can be seen as a necessary and

Spontaneous Movements during Sleep Guide Spinal Self-organization: Formation and Expression of a Memory Trace

During development, information about the three-dimensional shape and mechanical properties of the body is laid down in the synaptic connectivity of sensorimotor systems through adaptive mechanisms. In spinal reflex systems, this enables the fast transformation of complex sensory information into adequate correction of movements. In this thesis, it is shown, in a computer simulation, that an unsup

Acute Otitis Media. Aspects of diagnosis and prophylaxis

Acute otitis media (AOM) is one of the most common childhood diseases and the most common causes of antibiotic treatment in small children. Most children will experience one or two episodes of AOM during preschool age but some will suffer from repeated attacks, they will become otitis-prone. Complications with severe, sometimes fatal infections such as acute mastoiditis and meningitis are nowadays

Inhibitors of Human and Malaria Parasite Dihydroorotate Dehydrogenase

In the first part of the PhD work, small chemical entities (fragments) found to inhibit human dihydroorotate dehydrogenase (DHODH), were chemically optimized. As part of an ample program at Active Biotech to find new drugs against autoimmune diseases, expanded fragments were repeatedly designed, synthesized and evaluated in a human DHODH assay. Potent inhibitors were identified within three classe

Papaya policy brief 1

Microsoft Word - Papaya Policy Brief F - 31-08-17 2000 Zero draft Papaya Policy Brief 1 Feel the Churn: Gender, Age and Maize Productivity in Central-Eastern Africa, 2002 – 2013/15 Martin Prowse1, Aida Isinika2, Miriam Joshua3, Audrey Kalindi4, Elibariki Msuya5, Wapulumuka Mulwafu6 and Mukata Wamulume7 Gendered yield gaps within snapshot survey cross-sections hide considerable churn of households

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/papaya_policy_brief_1.pdf - 2025-04-29

191023 maa 2018 2019 hq

M al m ö A rt A ca de m y M al m ö A rt A ca de m y 20 18  –  2 01 9 20 18  –  2 01 9 Gertrud Sandqvist Professor of Art Theory and the History of Ideas; Supervisor for the Doctoral Programme Dr. Sarat Maharaj Professor of Visual Art and Knowledge Systems; Supervisor for the Doctoral Programme Joachim Koester Professor of Fine Arts Fredrik Værslev Professor of Fine Arts Emily Wardill Professor of

https://www.khm.lu.se/en/sites/khm.lu.se.en/files/191023_maa_2018_2019_hq.pdf - 2025-04-29