Aspects of sepsis/SIRS - An experimental study on fluid therapy, vitamin C and plasma volume in increased permeability
In sepsis, after major surgery or severe trauma, the human body may suffer from various degrees of generalized inflammation, a syndrome called Systemic Inflammatory Response Syndrome (SIRS). One feature of SIRS is increased capillary permeability, caused by disruption of the capillary endothelium due to e.g. bacterial toxins, cytokines, pro-inflammatory hormones and free oxygen radicals. This will