Filetype
A number of analogues of (Z)-5-decenyl acetate (1), a pheromone component of the turnip moth, Agrotis segetum, have been synthesised and tested by using single-cell electrophysiology, in order to investigate the relationships between structure and activity, and to elucidate the interactions between 1 and its receptor. Molecular mechanics and ab initio quantum mechanical calculations have been used
Several aspects related to the mesoporous silica material SBA-15 have been studied through the use of a wide range of experimental techniques, including low voltage high-resolution scanning electron microscopy, small angle X-ray scattering and nitrogen sorption. This work contains three parts, which are in many ways overlapping. The first part deals with the formation of SBA-15, it is found that a
Cytochromes P450 constitute a super-family of heme containing mixed function mono-oxygenases that is found in all branches of life. They introduce single oxygen atoms, mostly in the form of hydroxyl groups, into lipophilic substances and thereby render them more hydrophilic and susceptible to further reactions. Little is known about the bacterial cytochromes P450. I have in my thesis given an over
Ultrafine particles, their sources and fate in the atmosphere are currently key issues in atmospheric research owing to concern about their effects on human health and global climate. Traffic emissions are a dominating source of ultrafine particles, especially in urban areas. After release into the atmosphere, the particles are subjected to complex dilution and transformation processes that are of
The aim of this thesis was to evaluate the role of interatrial conduction defects in the genesis of lone paroxysmal atrial fibrillation (AF) using combined approach of non-invasive signal-averaged P-wave ECG, invasive electrophysiological (EP) studies, anatomical studies and animal experiments. Non-filtered signal-averaged P-wave ECG revealed irregularities in orthogonal P-wave morphology and the
The study analyses various aspects of international economics related to foreign direct investment, trade and specialisation. These issues are considered in view of the increased internationalisation - through trade and foreign direct investment - in recent decades. Special interest is devoted to the effects of economic integration. Chapter two examines the importance of FDI and country capabiliti
This dissertation studies statistical properties and applications of the Markov switching models for economic time series in five separate papers. The two main statistical themes are (i) the task of choosing the number of states to use in the model, and (ii) inference on time-varying transition probabilities. Our empirical applications span a wide array of topics in international finance and macro
Very little is known about a considerable part of all proteins and it is time consuming and expensive to study each individual protein to determine its function, structure and cellular role. Proteins retain structural, functional and sequential characteristics from ancestral proteins and hence two proteins that share a common ancestor, i.e. are homologs, will to some extent have similar sequen
Coagulation factor IX (FIX) is a vitamin K-dependent serine protease zymogen that circulates in plasma. Defects in FIX cause the bleeding disorder hemophilia B. FIX contains a Gla module, two Epidermal Growth Factor (EGF) -like modules and a serine protease region. In this thesis, studies have been performed on the N-terminal EGF module, which binds one Ca2+. — The present results show that bindin
A broad, distinctive material presentation is done, which is linked to some variables of psychological value, stating a research for the authenticity of Garborg in viewing him as well a symptom bearer as a symptom solver. An introduction to Garborg is meant to be an invitation, especially to those who are not so well acquainted with him as a person and a writer. Out from a period of about 110 year
Cognitive models of anxiety postulate that anxious individuals are inclined to pay more attention to negative than to positive emotional visual stimuli. The main aim of the present dissertation was to test this prediction, employing a measure of the direction of gaze. In studies I, II and III the participants were shown pairs of angry and happy faces on a screen. In Study IV the stimuli were pleas
This doctoral dissertation has aimed to contribute to a modern theory of the firm that balances a disciplining view of the firm with an enabling view of the firm. This has been approached through exploring how corporate governance mechanisms influence entrepreneurship at the organisational level, in a frame of property rights. As such, the research model that guides the dissertation depicts a mode
Radiotherapy is one of the major tools for treating cancer. Through research and technical development radiotherapy is becoming more advanced with new treatment techniques emerging. In the work presented in this thesis, well-known methods have been used, or modified for use, and new methods have been introduced in order to optimise the clinical use of an advanced radiotherapy treatment technique,
Groundwater depletion in arid and semiarid areas is of increasing concern. Increasing water demand due to increasing population and climate change impacts have intensified the water shortage problems and put further stress especially on groundwater. Water harvesting techniques have been traditional solutions to water scarcity problems in the arid and semiarid Middle East for thousands of years. Th
In Northern Ireland and South Africa obstacles to reconciliation were found in these elements of a “moral landscape”: – Experiences of trauma, separation and inequalities, – Divergent views of the conflict and of “the other”, – Opposing identifications and loyalties, – Norms for interaction, – Contestant interpretations of values such as “peace” and “justice”. This study describes how these obstac
In international commerce, various taxes and charges are levied on commodities; besides, goods may be subject to import and export restrictions. However, free-trade agreements may stipulate that some goods can be imported and exported free of charge. The regulations pertaining to different types of merchandise are reflected in the customs tariff of a state or customs union. The application of many
This dissertation aims at showing that Chrétien de Troyes' Conte du Graal does not, as often affirmed, uphold traditional chivalrous values, but discloses a problematic ideology, mostly as a result of multiple interactions at the textual level. In order to examine ideology, Le Conte du Graal is analysed in the light of the poetics elaborated by Vincent Jouve in his Poétique des valeurs (2001). Fol
Knowledge on intermetallic compounds and alloys is essential for technology leaps. The latest of these, the so-called digital revolution, started the period of the information age which is characterized by fast information transfer. The constant development of faster and smaller electronic devices comes with the drawback of increased amounts of waste, meaning products that used to by high-end tech
In 2005 two research groups independently reported the isolation of a series of structurally intriguing C-19 terpenolides from the plants Thapsia transtagana and Thapsia garganica. The compounds were shown to be potent inhibitors of the sarco/endoplasmic reticulum Ca2+-ATPases. The interesting biological properties and the unique structural characteristics of the transtaganolides/basiliolides (the
