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Joel white literature review

Captured metagenomics reveal the functional potential of methanogenic Archaea through temperate, sub-arctic and high arctic wetlands. Joel D. White Department of Physical Geography & Ecosystem Science Lund University This document was compiled as a literature review to assess the current state of knowledge in the field of environmental metagenomics. This project focuses upon the methane cycle and

https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/joel_white_literature_review.pdf - 2025-02-12

Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes

In type 2 diabetes (T2D), hepatic insulin resistance is strongly associated with nonalcoholic fatty liver disease (NAFLD). In this study, we hypothesized that the DNA methylome of livers from patients with T2D compared with livers of individuals with normal plasma glucose levels can unveil some mechanism of hepatic insulin resistance that could link to NAFLD. Using DNA methylome and transcriptome

Evolutionary history of the extinct Sardinian dhole

The Sardinian dhole (Cynotherium sardous) was an iconic and unique canid species that was endemic to Sardinia and Corsica until it became extinct at the end of the Late Pleistocene. Given its peculiar dental morphology, small body size, and high level of endemism, several extant canids have been proposed as possible relatives of the Sardinian dhole, including the Asian dhole and African hunting doThe Sardinian dhole (Cynotherium sardous)1 was an iconic and unique canid species that was endemic to Sardinia and Corsica until it became extinct at the end of the Late Pleistocene.2-5 Given its peculiar dental morphology, small body size, and high level of endemism, several extant canids have been proposed as possible relatives of the Sardinian dhole, including the Asian dhole and African huntin

Evaluation of protein and amino acid intake estimates from the EPIC dietary questionnaires and 24-h dietary recalls using different food composition databases

BACKGROUND AND AIMS: This study aimed to expand the European Prospective Investigation into Cancer and Nutrition (EPIC) nutrient database (ENDB) by adding amino acid (AA) values, using the U.S. nutrient database (USNDB). Additionally, we aimed to evaluate these new protein and AA intake estimates from the EPIC dietary questionnaires (DQ) and 24-h dietary recalls (24-HDR) using different matching p

Benchmarking sustainability in cities : The role of indicators and future scenarios

Scenarios are a useful tool to help think about and visualise the future and, as such, are utilised by many policymakers and practitioners. Future scenarios have not been used to explore the urban context in much depth, yet have the potential to provide valuable insights into the robustness of decisions being made today in the name of sustainability. As part of a major research project entitled Ur

Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight

Understanding the molecular determinants that underpin the clinical heterogeneity of non-muscle-invasive bladder cancer (NMIBC) is essential for prognostication and therapy development. Stage T1 disease in particular presents a high risk of progression and requires improved understanding. We present a detailed multi-omics study containing gene expression, copy number, and mutational profiles that

β-Amyloid and tau biomarkers and clinical phenotype in dementia with Lewy bodies

OBJECTIVE: In a multicenter cohort of probable dementia with Lewy bodies (DLB), we tested the hypothesis that β-amyloid and tau biomarker positivity increases with age, which is modified by APOE genotype and sex, and that there are isolated and synergistic associations with the clinical phenotype. METHODS: We included 417 patients with DLB (age 45-93 years, 31% women). Positivity on β-amyloid (A+)

A novel 33-Gene targeted resequencing panel provides accurate, clinical-grade diagnosis and improves patient management for rare inherited anaemias

Accurate diagnosis of rare inherited anaemias is challenging, requiring a series of complex and expensive laboratory tests. Targeted next-generation-sequencing (NGS) has been used to investigate these disorders, but the selection of genes on individual panels has been narrow and the validation strategies used have fallen short of the standards required for clinical use. Clinical-grade validation o

Early infantile epileptic encephalopathy due to biallelic pathogenic variants in PIGQ : Report of seven new subjects and review of the literature

We investigated seven children from six families to expand the phenotypic spectrum associated with an early infantile epileptic encephalopathy caused by biallelic pathogenic variants in the phosphatidylinositol glycan anchor biosynthesis class Q (PIGQ) gene. The affected children were all identified by clinical or research exome sequencing. Clinical data, including EEGs and MRIs, was comprehensive

Indirect treatment comparison of brexucabtagene autoleucel (ZUMA-2) versus standard of care (SCHOLAR-2) in relapsed/refractory mantle cell lymphoma

The SCHOLAR-2 retrospective study highlighted poor overall survival (OS) with standard of care (SOC) regimens among patients with relapsed/refractory (R/R) mantle cell lymphoma (MCL) who failed a covalent Bruton tyrosine kinase inhibitor (BTKi). In the ZUMA-2 single-arm trial, brexucabtagene autoleucel (brexu-cel; autologous anti-CD19 CAR T-cell therapy) demonstrated high rates of durable response

Real-world experience among patients with relapsed/refractory mantle cell lymphoma after Bruton tyrosine kinase inhibitor failure in Europe : The SCHOLAR-2 retrospective chart review study

Mantle cell lymphoma (MCL) after relapse is associated with poor prognosis. No standard of care exists and available evidence for treatments is limited, particularly in patients who fail Bruton tyrosine kinase inhibitor (BTKi) therapy. This multicentre retrospective chart review study, SCHOLAR-2, addresses this knowledge gap and reports on data collected from 240 patients with relapsed/refractory

Sex differences in associations between APOE ε2 and longitudinal cognitive decline

INTRODUCTION: We examined whether sex modifies the association between APOE ε2 and cognitive decline in two independent samples. METHODS: We used observational data from cognitively unimpaired non-Hispanic White (NHW) and non-Hispanic Black (NHB) adults. Linear mixed models examined interactive associations of APOE genotype (ε2 or ε4 carrier vs. ε3/ε3) and sex on cognitive decline in NHW and NHB p

LU-gemensamt Mejlutskick Nr 17-v19-2021

NYTT FRÅN LUNDS UNIVERSITET Mejlutskick på svenska och engelska som vänder sig till fakultetskommunikatörer vid Lunds universitet för vidarespridning i fakultets- och institutionskanaler – Nr 17 v 19 - 2021. CORONARELATERAT Höstens planering av utbildningen bör kunna utgå från viss återgång, förutsatt att smittläget tillåter det Uppdaterat rektorsbeslut 12 maj gör gällande att undervisning och exa

https://www.cec.lu.se/sites/cec.lu.se/files/2021-05/LU-gemensamt%20Mejlutskick%20Nr%2017-v19-2021.pdf - 2025-02-12

Protokoll-fakultetsstyrelsen-210609

Kallelse Sida 1 av 2 Fakultetsstyrelsen KALLELSE Datum 2021-06-01 Kallelse fakultetsstyrelsen Härmed kallas ledamöterna i fakultetsstyrelsen till sammanträde Tid: Onsdag den 9 juni, kl. 13.15. Plats: Zoom-möte. Länk: https://lu-se.zoom.us/j/67882291040 Förhinder meddelas till constance.holmback@science.lu.se Dagordning: 1. Utseende av justeringsperson 2. Fastställande av dagordning 3. Föregående m

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/2021-09/Protokoll-fakultetsstyrelsen-210609.pdf - 2025-02-12

Utbildningsplan 161111

Brevmall Utbildningsplan 1. Identifikation 1. Programmets namn Ämneslärarutbildning 2. Omfattning i högskole- poäng 270hp / 300hp / 330hp 3. Nivå Avancerad 4. Programkod LAÄ7N (Ämneslärarutbildning med inriktning mot årskurs 7-9) LAÄGN (Ämneslärarutbildning med inriktning mot gymnasieskolan) LAM79 (Ämneslärarutbildning i musik med inriktning mot årskurs 7-9) LAMGY (Ämneslärarutbildning i musik med

https://www.mhm.lu.se/sites/mhm.lu.se/files/2021-03/Utbildningsplan_161111.pdf - 2025-02-12

Anstallningsordning-och-allmanna-rad-vid-anstallning-av-larare-vid-samhallsvetenskapliga-fakulteten-

Anställningsordning och allmänna anvisningar vid anställdning av lärare vid Samhällsvetenskapliga fakulteten Postadress Box 117, 221 00 LUND Besöksadress Sandgatan 3 Gamla Kirurgen Telefon dir 046-222 72 06, växel 046-222 00 00 Telefax 046-222 44 11 E-post Anders.Kirchner@sam.lu.se Internet http://www.sam.lu.se Samh äl l svet enskapl iga fakul te t ss tyrel sen Anställningsordning och allmänna anv

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/anstallningsordning-och-allmanna-rad-vid-anstallning-av-larare-vid-samhallsvetenskapliga-fakulteten-2013.pdf - 2025-02-12

Jens Bartelson

Professor Kontaktinformation E-post: jens [dot] bartelson [at] svet [dot] lu [dot] se Telefon: +46 46 222 45 51Organisation Statsvetenskapliga institutionen Rumsnummer: 431 Hämtställe: 35 WebbplatsJens Bartelsons profil i Lunds universitets forskningsportalProfessor Intresseområden:Internationella relationerInternationellt politiskt tänkandeJens Bartelsons författarskap har huvudsakligen ägnats åt

https://www.svet.lu.se/jens-bartelson - 2025-02-13

Catherine Urquhart

Gästprofessor Kontaktinformation E-post: catherine [dot] urquhart [at] ics [dot] lu [dot] seOrganisation Institutionen för informatik Besöksadress: Ole Römers väg 6, Lund Hämtställe: 38 WebbplatsCatherine Urquharts profil i Lunds universitets forskningsportal Publikationer Visar av publikationer. Sorterade efter år och sen titel. Filtrera efter typ AllaArtikel i tidskriftBokDel av eller Kapitel i

https://www.ehl.lu.se/catherine-urquhart - 2025-02-13