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A head and neck cancer specific questionnaire module designed to be used in quality of life assessments before, during, and after radiotherapy and surgery, with or without combinations with chemotherapy has been developed in accordance with guidelines given by the EORTC Quality of Life Study Group. Relevant issues were generated by means of literature search, and interviews with specialists and pa

Background: During fetal hypoxia blood is redistributed to the brain ('brain-sparing'). Sequential changes of the cerebral and placental circulation in parallel in comparisons between basal conditions and acute hypoxic stress have not yet been thoroughly studied in human fetuses. Aim: To explore acute fetal middle cerebral artery (MCA) circulatory changes relative to umbilical artery (UA) blood fl

The nominal species Mosasaurus ivoensis from the latest early Campanian of the Kristianstad Basin in southern Sweden, is redescribed and assigned to the tylosaurine genus Tylosaurus on the basis of its dental and vertebral morphology. A partial skeleton (KUVP 1024) from the late Coniacian to earliest Campanian Smoky Hill Chalk Member of the Niobrara Formation in western Kansas, USA, was previously

Model studies of photosynthetic carbohydrate formation in the chloroplast of C3 plants have been performed to examine the expected response of the steady-state reaction flux to finite changes in concentration or activity of individual enzymes in a central metabolic network. The results indicate that flux control coefficients in this system cannot be reliably estimated experimentally even for the t

Heat conduction calorimetry is a convenient method to detect cement-admixture incompatibility. However, such instruments tend to be used mainly in chemical laboratories. This paper presents the design of a simple unthermostated heat conduction calorimeter that can simultaneously monitor the heat production rate in 14 samples of cement paste or mortar. As it is not thermostated, its performance is

Hjärtsvikt är ett syndrom vars diagnostik baseras på kliniska symtom och/eller fynd i kombination med en objektiv undersökning av hjärtat. Diagnosen diastolisk hjärtsvikt har i praktiken visat sig svår att ställa i många fall. En orsak till detta är oklarheter i definitionen av tillståndet. Många patienter med diastolisk hjärtsvikt har även en nedsättning av den systoliska vänsterkammarfunktionen,

This thesis argues that it is relevant to make aspectual distincions in terms of progressivity and imperfectivity not only in languages like Russian or English but also in languages like German and Swedish, which traditionally are not considered aspect languages. This means that a distinction has to be made between aspectuality as a conceptual category and the grammatical category aspect (?Aspekt?

Two central steps in the hydrolysis of lactam antibiotics catalyzed by mononuclear metallo--lactamases, formation of the tetrahedral intermediate and its breakdown by proton transfer, are studied for model systems using the density functional B3LYP method. Metallo--lactamases have two metal ion binding sites, one of which is occupied in the mononuclear species. In this work it is assumed that cata

The efficient in vitro inhibition of hepatitis B virus DNA polymerase by trisodium phosphonoformate (PFA, INN: foscarnet sodium) and its low toxicity suggested that PFA could be used as a therapeutic agent for hepatitis B infection. PFA was also found to inhibit woodchuck hepatitis virus (WHV) DNA polymerase in vitro. As a model to test PFA's eventual effect, chronically WHV infected woodchucks we

The helicity structure of the diffractive electroproduction of rho mesons, e + p --> e + rho + Y, is studied in a previously unexplored region of large four-momentum transfer squared at the proton vertex, t: 0 < t' < 3 GeV2, where t' = - min. The data used are collected with the HI detector at HERA in the kinematic domain 2.5 < Q(2) < 60 GeV2, 40 < W < 120 GeV No t dependence of the r(00)(04) spin