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Merging Percolation on Z(d) and Classical Random Graphs: Phase Transition

We study a random graph model which is a superposition of bond percolation on Z(d) with parameter p, and a classical random graph G(n,c/n). We show that this model, being a homogeneous random graph, has a natural relation to the so-called "rank I case" of inhomogeneous random graphs. This allows us to use the newly developed theory of inhomogeneous random graphs to describe the phase diagram on th

Technical Skills Assessment in a Coronary Angiography Simulator for Construct Validation.

INTRODUCTION: The aim of this study was to evaluate technical skills in a coronary angiography (CA) simulator to establish the performance level of trainees and experts in virtual CA.The traditional master-apprentice way of learning CA is by practicing on patients despite a known risk for complications during training. Safe CA training is warranted, and simulators might be one possibility. Simulat

CO-Induced Smoluchowski Ripening of Pt Cluster Arrays on the Graphene/Ir(111) Moire

Regular Pt cluster arrays grown on the moire template formed by graphene on Ir(111) were tested for their stability with respect to CO gas exposure. Cluster stability and adsorption-Induced processes were analyzed as a function of cluster size, with In situ scanning tunneling microscopy and X-ray photoelectron spectroscopy. Small clusters containing fewer than 10 atoms were unstable upon CO adsorp

Alkaline sphingomyelinase (NPP7) promotes cholesterol absorption by affecting sphingomyelin levels in the gut. A study with NPP7 knockout mice.

We previously showed that dietary sphingomyelin (SM) inhibited cholesterol absorption in animals. The key enzyme hydrolyzing SM in the gut is alkaline sphingomyelinase (alk-SMase, NPP7). Here using fecal dual-isotope ratio method we compared cholesterol absorption in the wild type (WT) and alk-SMase knockout (KO) mice. The animals were fed an emulsion containing (14)C-cholesterol and (3)H-sitoster

Modeling the influence of TR and excitation flip angle on the magnetization transfer ratio (MTR) in human brain obtained from 3D spoiled gradient echo MRI

Attempts to optimize the magnetization transfer ratio (MTR) obtained from spoiled gradient echo MRI have focused on the properties of the magnetization transfer pulse. In particular, continuous-wave models do not explicitly account for the effects of excitation and relaxation on the MTR. In this work, these were modeled by an approximation of free relaxation between the radiofrequency pulses and o

Regulation of complement by COMP allows for a novel molecular diagnostic principle in rheumatoid arthritis.

OBJECTIVE:: Cartilage oligomeric matrix protein (COMP) is a structural component of cartilage where it catalyzes collagen fibrillogenesis. Elevated amounts of COMP are found in serum during increased turnover of cartilage associated with active joint diseases, such as rheumatoid arthritis (RA) and osteoarthritis (OA). In this study we investigated the ability of COMP to regulate complement. Such c

Familial colorectal cancer type X: genetic profiles and phenotypic features.

Heredity is a major cause of colorectal cancer, but although several rare high-risk syndromes have been linked to disease-predisposing mutations, the genetic mechanisms are undetermined in the majority of families suspected of hereditary cancer. We review the clinical presentation, histopathologic features, and the genetic and epigenetic profiles of the familial colorectal cancer type X (FCCTX) sy

Is patient satisfaction in primary care dependent on structural and organizational characteristics among providers? Findings based on data from the national patient survey in Sweden.

In parallel to market-like reforms in Swedish primary care, the gathering and compilation of comparative information about providers, for example through survey tools, has been improved. Such information is increasingly being used to guide individuals' choice of provider and payers' assessments of provider performance, often without critically reflecting about underlying factors affecting the resu

Inverse Problems for Quantum Trees II: Recovering matching conditions for star graphs

The inverse problem for the Schrodinger operator on a star graph is investigated. It is proven that such Schrodinger operator, i.e. the graph, the real potential on it and the matching conditions at the central vertex, can be reconstructed from the Titchmarsh-Weyl matrix function associated with the graph boundary. The reconstruction is also unique if the spectral data include not the whole Titchm

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

Quantitative ultrasound of the heel captures heel bone properties that independently predict fracture risk and, with bone mineral density (BMD) assessed by X-ray (DXA), may be convenient alternatives for evaluating osteoporosis and fracture risk. We performed a meta-analysis of genome-wide association (GWA) studies to assess the genetic determinants of heel broadband ultrasound attenuation (BUA; n

What has inflammation to do with traumatic brain injury?

INTRODUCTION: Inflammation is an stereotypical response to tissue damage and has been extensively documented in experimental and clinical traumatic brain injury (TBI), including children. DISCUSSION: The initiation and orchestration of inflammation in TBI, as in other tissues, is complex and multifactorial encompassing pro- and anti-inflammatory cytokines, chemokines, adhesion molecules, complemen

The protective effect of immunoglobulin in murine tuberculosis is dependent on IgG glycosylation

Antibodies have demonstrated having a protective effect in animal models of tuberculosis (TB). These experiments have considered the specificity of antigen recognition and the different isotypes and subclasses as significant contributors of this effect. However, the carbohydrate chain heterogeneity on the Fc region of IgG (Fc-IgG) can play an important role in modulating the immune response. Patie

Picking personalities apart: estimating the influence of predation, sex and body size on boldness in the guppy Poecilia reticulata

Predation is a strong selective force in most natural systems, potentially fueling evolutionary changes in prey morphology, life history and behaviour. Recent work has suggested that contrasting predation pressures may lead to population differentiation in personality traits. However, there are indications that these personality traits also differ between sexes and not necessarily in a consistent