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Background: Antithrombin concentrate (AT) is used to treat heparin resistance (HR) in cardiac surgery. It is usually given slowly due to the fear of anaphylaxis. This may delay cardiac catheterisation and the start of cardiopulmonary bypass (CPB). HR is often defined as the failure to reach or maintain a target activated clotting time (ACT) despite a standard dose of heparin. It is not generally p
abstract is not available
Popular Abstract in Swedish Akut bukspottkörtelinflammation, akut pankreatit (AP), är en sjukdom med varierande kliniska presentationer; från en mild och ödematös, till en svår och nekrotiserande form. Ungefär 75% av patienter med AP utvecklar en mild, självbegränsande sjukdom, men hos resten av patienterna progredierar sjukdomen till en svår form och dödligheten är så hög som 30% i denna grupp avAcute pancreatitis (AP) is an inflammatory disease with variable severity ranging from mild interstitial edematous to severe necrotizing disease. The overall mortality rate of AP is 8-9%. Specific treatment of AP is lacking which is partly related to an incomplete understanding of the basic pathophysiology behind the disease. It is widely held that premature intra-cellular trypsinogen activation a
Recension av Pierre Broué; Trotskij – en biografi.
The duration of cell death may allow deducing the underlying degenerative mechanism. To find out how long a photoreceptor takes to die, we used the rdl mouse model for retinal neurodegeneration, which is characterized by phosphodiesterase-6 (PDE6) dysfunction and photoreceptor death triggered by high cGMP levels. Based on cellular data on the progression of cGMP accumulation, cell death, and survi
It is known that warm and humid environment reduces human physical performance. The present study examined whether the use of an ice-vest in such conditions can improve cycling performance. Seven participants cycled with consecutive, non-stop, 10-minute cycles of nine minutes at 60% of their (V) over dot O-2 max punctuated by a one-minute sprint at 80% (V) over dot O-2 max. The cycling protocol wa
Aim: To investigate the application of skin-to-skin care (SSC) in the Nordic countries, the existence of guidelines for SSC and the attitudes of neonatal staff towards SSC. Methods: One questionnaire was distributed at unit level and one at staff level in all Nordic neonatal intensive care units (n = 109). Results: The unit questionnaire was answered by 95 (87%) units and the staff questionnaire b
Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) regulate islet function after carbohydrate ingestion. Whether incretin hormones are of importance for islet function after ingestion of noncarbohydrate macronutrients is not known. This study therefore examined integrated incretin and islet hormone responses to ingestion of pure fat (oleic acid; 0.88 g/kg) or pr
Abstract in UndeterminedTolerance has the potential to affect both economic growth and wellbeing. It is therefore important to discern its determinants. We contribute to the literature by investigating whether the degree to which economic institutions and policies are market-oriented is related to different measures of tolerance. Cross-sectional and first-difference regression analysis of up to 69
Background: Many older adults are physically inactive and inactivity increases with age. This knowledge comes from cross-sectional studies. Cross-sectional studies may miss important trajectories within the older adults as a result of retirements, and poor health impact of promotional efforts. The aim of this study was to analyse, longitudinally, the annual effects of age group and birth cohort on
Popular Abstract in Swedish Populärvetenskaplig sammanfattning Ledgångsreumatism (Reumatoid Artrit, RA) leder hos många patienter till omfattande ledskador, vilket kan ge upphov till behov av operation. Med tillgång till nya och bättre läkemedel för behandling av RA förefaller behovet av reumakirurgiska operationer ha minskat, åtminstone för vissa typer av ingrepp. Det är dock tydligt att det finnOrthopedic surgery is used effectively in many patients with severe rheumatoid arthritis RA). The aim of modern pharmacologic treatment is to prevent joint destruction and reduce the need for orthopedic surgery. Patient reported outcomes (PROs) are important measures of the burden of RA. A large, community based RA cohort, established in 1997, was investigated. Patients were classified according t
Rationale and Objective: Neuropsychiatric systemic lupus erythematosus (NPSLE) is a diagnostically challenging, severe, and life-threatening condition, which is currently lacking a "gold standard." Our aim with this study is to look for magnetic resonance (MR) perfusion differences in NPSLE, SLE, and healthy control (HC) patients and correlate our findings with clinical parameters. Materials and M
During grinding processes, numerous grains interact with the workpiece material producing mechanical and thermal loads on the surface. In the field of thermal simulation of grinding processes, a widely used approach is to substitute numerous cutting edges by a single moving distributed heat source of a specific geometrical shape referring to the theory of Carslaw and Jaeger. This heat source is th
We focus on exclusive production of neutral technipion (pi) over tilde (0) in pp collisions at the LHC, i.e. on pp -> pp (pi) over tilde (0) reaction. The dependence of the cross section on parameters of recently proposed vector-like Technicolor model is studied. Characteristic features of the differential distributions are discussed. For not too large technipion masses the diphoton decay channel
Due to its high hydrogen content and its favourable overall thermodynamics magnesium tetrahydroborate has been considered interesting for hydrogen storage applications. In this work we show that unsolvated amorphous magnesium tetrahydroborate can be obtained by reactive ball milling of commercial MgB2 under 100 bar hydrogen atmosphere. The material was characterized by solid-state NMR which showed
