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Tuberculosis along the continuum of HIV care in a cohort of adolescents living with HIV in Ethiopia

SETTING: Eight health facilities in Ethiopia. OBJECTIVE: To determine tuberculosis (TB) incidence rates and associated factors among adolescents living with the human immunodeficiency virus (ALHIV). DESIGN: This was a retrospective cohort study. Adolescents enrolled in HIV care between January 2005 and 31 December 2013 constituted the study population. The main outcome variable was TB diagnosis du

Long-term efficacy and safety of α1 proteinase inhibitor treatment for emphysema caused by severe α1 antitrypsin deficiency : an open-label extension trial (RAPID-OLE)

Background Purified α1 proteinase inhibitor (A1PI) slowed emphysema progression in patients with severe α1 antitrypsin deficiency in a randomised controlled trial (RAPID-RCT), which was followed by an open-label extension trial (RAPID-OLE). The aim was to investigate the prolonged treatment effect of A1PI on the progression of emphysema as assessed by the loss of lung density in relation to RAPID-

Study of endoplasmic reticulum and mitochondria interactions by in situ proximity ligation assay in fixed cells

Structural interactions between the endoplasmic reticular (ER) and mitochondrial membranes, in domains known as mitochondria-associated membranes (MAM), are crucial hubs for cellular signaling and cell fate. Particularly, these inter-organelle contact sites allow the transfer of calcium from the ER to mitochondria through the voltage-dependent anion channel (VDAC)/glucose-regulated protein 75 (GRP

Opportunities and challenges of using ultrafiltration for the concentration of diluted coating materials

The use of cross-flow ultrafiltration for the recovery of coating material from aqueous streams started about 30 years ago with electro-deposition paint in the automotive industry. This early success can be related to both environmental and economical advantages of using ultrafiltration. Ultrafiltration recovers and concentrates electro-deposition paint on the retentate side and produces purified

Sustainable Consumption and Value Propositions: Exploring Product–Service System Practices Among Swedish Fashion Firms

Since sustainable consumption (SC) research focuses primarily on consumer purchasing behaviors, there is a gap regarding how firms attempt to shape sustainable consumption in practice. Utilizing nine case studies, this gap is addressed by exploring the use of value propositions entailing product–service systems among Swedish fashion firms. The value propositions in use by the firms suggest that su

Hematopoietic Cell-Specific Deletion of Toll-like Receptor 4 Ameliorates Hepatic and Adipose Tissue Insulin Resistance in High-Fat-Fed Mice

Chronic low-grade inflammation, particularly in adipose tissue, is an important modulator of obesity-induced insulin resistance. The Toll-like receptor 4 (Tlr4) is a key initiator of inflammatory responses in macrophages. We performed bone marrow transplantation (BMT) of Tlr4lps-del or control C57Bl/10J donor cells into irradiated wild-type C57Bl6 recipient mice to generate hematopoietic cell-spec

Contacts, Identity and Hybridity : objects from South-western Finland in the Birka Graves

The study concludes that there were contacts between Birka and western Finland throughout more or less the whole existence of the town. The earliest evidence of these contacts is from the 760s and the latest from the middle of the tenth century. Unlike other eastern material in Birka, which became much more frequent during the second half of the ninth century the contacts with Finland were constan

Rereading a tree-ring database to illustrate depositional histories of subfossil trees

Late Quaternary tree-ring chronologies have been constructed using data collected from subfossil trees preserved under favourable conditions in lake sediments and peat deposits. Tree-ring widths and densities are commonly used for reconstructions of past climate variability. An alternative way of using these data is to explore the replication curves of these chronologies. Here, we make use of prev

Effects of pitch and corrugation depth on heat transfer characteristics in six-start spirally corrugated tube

Spirally corrugated tube is one of the most important parts of coaxial heat exchangers. It can greatly improve the heat transfer efficiency of heat exchangers. Here, a novel spirally corrugated tube with six-start is proposed. However, up to now, there is little literature about the heat transfer performance and flow field of this novel six-start spirally corrugated tube. In this paper, the effect

Diffusion MRI and Poroelastic Biomechanics of Articular Cartilage

Cartilage is a poroelastic material for which application of load leads to fluid flow within and out from the porous solid matrix. The redistribution of fluids is a major factor in determining the mechanical properties and friction coefficients, which consequently depend in a complex way on the details of the load history and geometry. Although current poroelastic models for cartilage generally ag

Enabling dissimilar fibre embedding and explicit fibre layout in ultrasonic consolidation

Ultrasonic Consolidation (UC) is a manufacturing technique based on the ultrasonic metal welding of a sequence of metal foils which are bonded to one another in a layer by layer manner. It combines the ability of additive and subtractive manufacturing techniques to create complex three-dimensional shapes. Due to moderate applied pressures and the relatively low temperatures experienced by a sample

Nya Namn i Periodiska Systemet

Artikeln ger en sammanfattning av IUPAC:s rekommendationer år 1994 för namnen på de nya grundämnena 101-109, de s.k. transfermierna. Rekommendationerna publiceras senare under 2014 i Pure and Applied Chemistry, Vol 66 Nr 12. Dessa rekommendationer skall under år 1995 ytterligare granskas/ratificeras av IUPACs Council, vilket slutligen kan resultera i ändringar eller omflyttningar.