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A review of multiphase flow and deposition effects in film-cooled gas turbines

This paper presents a review of particle deposition research in film-cooled gas turbines based on the recent open literature. Factors affecting deposition capture efficiency and film cooling effectiveness are analyzed. Experimental studies are summarized into two discussions in actual and virtual deposition environments. For investigation in virtual deposition environments, available and reasonabl

Racial and Sociodemographic Differences of Semen Parameters Among US Men Undergoing a Semen Analysis

Objective: To characterize sociodemographic differences in semen parameters among US men undergoing a semen analysis. Materials and Methods: Men who provided a semen sample were identified from insurance claims between 2007 and 2016. Differences in semen parameters were characterized according to age, race, education, and region. Mean semen parameters and proportions of men with suboptimal paramet

A Case Study of Far-Field Temperatures in Progressing Fires

The non-uniform conditions and potential progression of fires in larger spaces calls for modelling methods extending outside of the traditional compartment fire framework. Even though a handful of studies in the area exist there is still little guidance available on how progressing fires in large enclosures can be modelled. Three different methods to calculate far-field gas temperature in large en

Use of terbinafine and risk of death in patients with prostate cancer : A population-based cohort study

Terbinafine is used for the treatment of several superficial fungal infections. In silico analyses and animal models suggest that terbinafine might have an anti-tumor effect. We aimed to explore whether subsequent administration of terbinafine might be associated with a lower mortality rate in patients with prostate cancer. We identified patients diagnosed with prostate cancer between July 2005 an

Effect of combined hole configuration on film cooling with and without mist injection

Turbine blades operate under a harsh environmental condition, and the inlet temperature of gas turbines is increasing with requirement of high engine effi-ciency. Some cooling schemes are adopted to prevent these blades from the ther-mal erosion of the hot mainstream. Film cooling technology is used widely and effectively in gas turbines. The coolant air is suppressed to the wall by the main-strea

A targeted metabolomic protocol for quantitative analysis of volatile organic compounds in urine of children with celiac disease

Volatile organic compounds (VOCs) in biological samples have gained popularity for disease monitoring and diagnosis. Celiac disease (CD) is one of the many prevalent health conditions which are challenging to diagnose. The aim of this study was to optimize a solid phase microextraction followed by gas chromatography-mass spectrometry, for quantitative analysis of a wide range of VOCs in the urine

Affordances, experimentation and actualization of FinTech : A blockchain implementation study

Blockchain, the technology underlying bitcoin, is an emerging financial technology (FinTech) that is poised to have strategic impacts on organizations. Because it is a new phenomenon, there are few studies on blockchain, and those studies have focused mainly on the technology's potential impacts, whereas how to effectively implement it in an organization remains unknown. Our study intends to fill

The Unequal Distribution of Speaking Time in Parliamentary-Party Groups

Parliamentary debates provide an arena where Members of Parliament (MPs) present, challenge, or defend public policies. However, the “plenary bottleneck” allows the party leadership to decide who participates in a debate. We argue that in this decision the timing of a debate matters: in proximity of elections, the leadership should be concerned with maintaining its brand name and therefore restric

Thermal assessment of glass façade panels under radiant heating : Experimental and preliminary numerical studies

Nowadays, glass is increasingly being used as a load-bearing material for structural components in buildings and façades. Different structural member solutions (such as panels, beams, columns) and loading conditions were the subjects of several research studies in recent years. Most of them, however, were typically limited to experimental testing and numerical simulations on glass elements and ass

Effect of intravascular cooling on microvascular obstruction (MVO) in conscious patients with ST-elevation myocardial infarction undergoing primary PCI : Results from the COOL AMI EU pilot study

Objective: COOL AMI EU pilot was a multi-center, randomized controlled trial to assess feasibility and safety of rapid intravascular therapeutic hypothermia (TH) in conscious patients with anterior ST-elevation myocardial infarction (STEMI) undergoing primary PCI (PPCI). We report the effect of hypothermia upon microvascular obstruction (MVO). Methods: Conscious patients with anterior STEMI and sy

The Core of Parents’ Main Concerns When Having a Child With Cataract and Its Clinical Implications

Purpose: To investigate the main concerns associated with being a parent of a child with cataract and how the parents deal with these concerns. Design and method: Twenty-three parents; 6 mothers, 5 fathers and 6 couples with a child with cataract were included in this study. The parents included some with a personal experience of cataract and some without. Data was collected through 17 in-depth in

Healthcare provider perspectives on the uptake of the human papillomavirus vaccine among newcomers to Canada : a qualitative study

Human papillomavirus is among the most common sexually transmitted infections in the world. Newcomers, defined in Canada as foreign-born individuals who are either immigrants or refugees, but may also include students and undocumented migrants, face numerous barriers to HPV vaccination. This study sought to understand, from the perspective of healthcare providers, barriers and facilitators to HPV

PVC flooring at home and uptake of phthalates in pregnant women

Phthalates are used as plasticizers in polyvinyl chloride (PVC) materials and it is known that phthalates may migrate into the surrounding environment and then become a source for human uptake. The aim of the study was to investigate whether residential PVC flooring was related to the urinary levels of phthalate metabolites determined in pregnant women. The data were from the Swedish SELMA study w

Organic Fraction of Municipal Solid Waste Recovery by Conversion into Added-Value Polyhydroxyalkanoates and Biogas

The integrated-multistage process proposed herein is a practical example of a biorefinery platform in which the organic fraction of municipal solid waste (OFMSW) is used as a valued source for polyhydroxyalkanoates (PHA) and biogas production. Technical and economical feasibilities of this approach have been demonstrated at pilot-scale, providing a possible upgrade to traditional biowaste manageme

Effect of spherical blockage configurations on film cooling

With increasing inlet temperature of gas turbines, turbine blades need to be effec-tively protected by using cooling technologies. However, the deposition from the fuel impurities and dust particles in the air is often found inside film holes, which results in partial hole blockage. In this paper, the deposition geometry is simpli-fied as a rectangular channel, and the effect of three blockage rat

Impact of comorbidity on disease characteristics, treatment intent and outcome in diffuse large B-cell lymphoma : a Swedish lymphoma register study

Background: Comorbidity impacts overall survival amongst patients with diffuse large B-cell lymphoma (DLBCL). However, associations of comorbidity with lymphoma characteristics, treatment selection and lymphoma-specific mortality are less well known. Objective: To examine the impact of comorbidity on DLBCL characteristics, treatment intent and cause of death. Methods: We identified 3905 adult pati

Mutational mechanisms of amplifications revealed by analysis of clustered rearrangements in breast cancers

BackgroundComplex clusters of rearrangements are a challenge in interpretation of cancer genomes. Some clusters of rearrangements demarcate clear amplifications of driver oncogenes but others are less well understood. A detailed analysis of rearrangements within these complex clusters could reveal new insights into selection and underlying mutational mechanisms.Patients and methodsHere, we systema

Late Mortality after Allogeneic Blood or Marrow Transplantation for Inborn Errors of Metabolism : A Report from the Blood or Marrow Transplant Survivor Study-2 (BMTSS-2)

Allogeneic blood or marrow transplantation (BMT) is currently considered the standard of care for patients with specific inborn errors of metabolism (IEM). However, there is a paucity of studies describing long-term survival and cause-specific late mortality after BMT in these patients with individual types of IEM. We studied 273 patients who had survived ≥2 years after allogeneic BMT for IEM perf

Negotiating Conventions : cleanliness, sustainability and everyday life

Cleanliness has seen a rapid increase in both developed and developing countries, along with a parallel rise in not only water and energy but also cleaning products consumed. Water and energy supply as well as dealing with waste are environmentally critical in securing a sustainable future. This dissertation aims to contribute to sustainability by providing new insights around how conventions chan