Background: Familial confounding is confounding due to genetics or environmental exposures shared by family members. We aimed to study whether familial confounding explains the association between body mass index (BMI) and severe hip osteoarthritis (OA). Methods: We linked data from the Norwegian Arthroplasty Registry with the Norwegian Twin Registry on the National ID-number in 2014, generating a

ExtendJ (formerly JastAddJ) is an extensible Java compiler, supporting full Java source-to-bytecode compilation. ExtendJ enables researchers and developers to easily build powerful language extensions, custom static analyses, and other tools for Java. ExtendJ is built with Reference Attribute Grammars and Aspect Oriented Programming, enabling easy extension development.

A 59-year-old female secretary was referred for evaluation and treatment of a non-healing painful ulcer on the medial aspect of her right lower leg. The ulcer had been recurrent almost every year for the past 9 years, often healing during the winter season. She had since early childhood been overweight (currently 87 kg, 170 cm, body mass index 30) and had difficulty in using compression stocking.

A search for the decay of the Standard Model Higgs boson into a bb pair when produced in association with a W or Z boson is performed with the ATLAS detector. The analysed data, corresponding to an integrated luminosity of 36.1 fb-1, were collected in proton-proton collisions in Run 2 of the Large Hadron Collider at a centre-of-mass energy of 13TeV. Final states containing zero, one and two charge

High body mass index (BMI) is associated with development of hematological malignancies (HMs). However, although BMI is a well-established measurement of excess weight, it does not fully reflect body composition and can sometimes misclassify individuals. This study aimed at investigating what body composition measurements had highest association with development of HM. Body composition measurement

This paper describes the implementation and performance of a particle flow algorithm applied to 20.2 fb- 1 of ATLAS data from 8 TeV proton–proton collisions in Run 1 of the LHC. The algorithm removes calorimeter energy deposits due to charged hadrons from consideration during jet reconstruction, instead using measurements of their momenta from the inner tracker. This improves the accuracy of the c

The distribution of exoplanet masses is not primordial. After the initial stage of planet formation, gravitational interactions between planets can lead to the physical collision of two planets, or the ejection of one or more planets from the system. When this occurs, the remaining planets are typically left in more eccentric orbits. In this report we demonstrate how the present-day eccentricities

Massive star clusters are observed in galaxies spanning a broad range of luminosities and types, and are assumed to form in dense gas-rich environments. Using a parsec-resolution hydrodynamical simulation of an isolated gas-rich low-mass galaxy, we discuss here the non-linear effects of stellar feedback on the properties of star clusters with a focus on the progenitors of nuclear clusters. Our sim

We combine parallaxes from the first Gaia data release with the spectrophotometric distance estimation framework for stars in the fifth RAVE survey data release. The combined distance estimates aremore accurate than either determination in isolation - uncertainties are on average two times smaller than for RAVE-only distances (three times smaller for dwarfs), and 1.4 times smaller than TGAS parall

High-precision measurements by the ATLAS Collaboration are presented of inclusive W+→ ℓ+ν, W-→ ℓ-ν¯ and Z/ γ∗→ ℓℓ (ℓ= e, μ) Drell–Yan production cross sections at the LHC. The data were collected in proton–proton collisions at s=7TeV with an integrated luminosity of 4.6fb-1. Differential W+ and W- cross sections are measured in a lepton pseudorapidity range | ηℓ| < 2.5. Differential Z/ γ∗ cross se

The development of large, software-intensive systems is a complex undertaking that we generally tackle by a divide and conquer strategy. Companies thereby face the challenge of coordinating individual aspects of software development, in particular between requirements engineering (RE) and software testing (ST). A lack of REST alignment can not only lead to wasted effort but also to defective softw

To assess the benefits of introducing Agile practices, it is important to get a clear understanding of the baseline situation, i.e. the situation before their introduction. Without a clear baseline, we cannot properly assess the extent of impacts, both positive and negative, of introducing Agile practices. This paper provides a preliminary guideline to help researchers in capturing and reporting b

In recent years, there has been significant shift from rigid development (RD) toward agile. However, it has also been spotted that agile methodologies are hardly ever followed in their pure form. Hybrid processes as combinations of RD and agile practices emerge. In addition, agile adoption has been reported to result in both benefits and limitations. This exploratory study (a) identifies developme

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Context: Value stream mapping (VSM) as a tool for lean development has led to significant improvements in different industries. In a few studies, it has been successfully applied in a software engineering context. However, some shortcomings have been observed in particular failing to capture the dynamic nature of the software process to evaluate improvements i.e. such improvements and target value

Heterogeneous systems comprising sets of inherent subsystems are challenging to integrate. In particular, testing for interoperability and conformance is a challenge. Furthermore, the complexities of such systems amplify traditional testing challenges.We explore (1) which techniques are frequently discussed in literature in context of heterogeneous system testing that practitioners use to test the

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