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The facultative intracellular bacterium Listeria monocytogenes (Lm) may cause severe infection in humans and livestock. Control of acute listeriosis is primarily dependent on innate immune responses, which are strongly regulated by NF-kappa B, and tissue protective factors including fibrin. However, molecular pathways connecting NF-kappa B and fibrin production are poorly described. Here, we inves
The financial crisis starting in 2008 made many European countries opt for a change of exchange rate regime. The choice of price measure as an entry requirement to the European Economic and Monetary Union (EMU) and as input in the monetary policy decision process re‐appeared as an important political and research issue. This paper aims to argue that, considering the importance of producer prices i
Autoimmunity against pancreatic islet beta cells is strongly associated with proinsulin, insulin, or both. The insulin autoreactivity is particularly pronounced in children with young age at onset of type 1 diabetes. Possible mechanisms for (pro)insulin autoimmunity may involve beta-cell destruction resulting in proinsulin peptide presentation on HLA-DR-DQ Class II molecules in pancreatic draining
In 2005, methylisothiazolinone (MI) on its own came into use as a preservative. Prior to that, MI was always present together with methylchloroisothiazolinone (MCI). Can the pattern of reactivity to the separate active ingredients in allergic patients tell us something about the primary sensitizer?
Radioactive beams of B-14,B-15 produced by fragmentation of a primary Ar-40 beam were directed onto a Pb target to investigate the neutron breakup within the Coulomb field. The experiment was performed at the LAND/(RB)-B-3 setup. Preliminary results for the Coulomb dissociation cross sections as well as for the astrophysically interesting inverse reactions, B-13,B-14(n,gamma), are presented.
Specially tailored polyelectrolytes are becoming important as energy-related materials. Here we explore a synthetic strategy to prepare fully aromatic polymers containing single phenylene rings in the backbone functionalized with four sulfonic acid groups. Thioether bridges of semifluorinated poly(arylene thioether)s were oxidized to sulfone bridges, followed by substitution of all fluorines by Na
RDW is a new and easily available risk marker for adverse cardiovascular outcomes and we agree that this may encourage a wider use in clinical practice. As pointed out by Balta et al [2], the underlying causal links are unclear. The causal links could hypothetically involve some of the factors mentioned by Balta et al [2], but also properties of the red cells per se. This article is protected by c
Despite the vast amount of research over the past fifteen years, there is still lively debate surrounding the role of social capital on individual health outcomes. This seems to stem from a lack of consistency regarding the definition, measurement and plausible theories linking this contextual phenomenon to health. We have further identified a knowledge gap within this field - a distinct lack of r
High-latitude peatlands contain about one third of the world's soil organic carbon, most of which is derived from partly decomposed Sphagnum (peat moss) plants. We conducted a meta-analysis based on a global data set of Sphagnum growth measurements collected from published literature to investigate the effects of bioclimatic variables on Sphagnum growth. Analysis of variance and general linear mod
Poor nutritional status is widespread among the elderly and is associated with increased morbidity and mortality. The aim of this study was to longitudinally describe the nutritional status in elderly people living in nursing homes. Nutritional status was recorded longitudinally in elderly people living in 11 different nursing homes in Sweden. Participants were examined at baseline by specially tr
Achieving efficient electrochemical communication between redox enzymes and various electrode materials is one of the main challenges in bioelectrochemistry and is of great importance for developing electronic applications. Cellobiose dehydrogenase (CDH) is an extracellular flavocytochrome composed of a catalytic FAD containing dehydrogenase domain (DH(CDH)), a heme b containing cytochrome domain
This paper investigates iconicity as a possible driving force behind the rebuilding of deictic systems and forms in individual languages. A comparison of a reconstructed Proto-Indo-European deictic system (based mainly on Beekes, Comparative Indo-European Linguistics: An Introduction, 1995) compared with the systems of attested Indo-European languages makes it clear that both systems and forms hav
This paper develops a welfare theoretic foundation for cost-effectiveness analysis (CEA) when survival is not affected. With this foundation, all costs and their corresponding utility-terms should be included. A key question, though, is whether these utility-terms are consistent with quality-adjusted life year (QALY) (utility) theory or not. The results show that health care costs and changes in t
The fast development of new organic sensitizers leads to the need for a better understanding of the complexity and significance of their adsorption processes on TiO2 surfaces. We have investigated a prototype of the triphenylamine-cyanoacrylic acid (donor-acceptor) on rutile TiO2 (110) surface with special attention on the monolayer region. This molecule belongs to the type of dye, some of which s
A new global two-fluid electromagnetic turbulence code, CENTORI, has been developed for the purpose of studying magnetically-confined fusion plasmas on energy confinement timescales. This code is used to evolve the combined system of electron and ion fluid equations and Maxwell equations in toroidal configurations with axisymmetric equilibria. Uniquely, the equilibrium is co-evolved with the turbu
Anaemia is a chief determinant of global ill health, contributing to cognitive impairment, growth retardation and impaired physical capacity. To understand further the genetic factors influencing red blood cells, we carried out a genome-wide association study of haemoglobin concentration and related parameters in up to 135,367 individuals. Here we identify 75 independent genetic loci associated wi
Stars ascending the red giant branch develop an inversion in mean molecular weight (mu) owing to the burning of He-3 in the region immediately above their hydrogen-burning shells. This inversion may drive thermohaline mixing and thereby be responsible for the extra mixing which is observationally indicated on the red giant branch. In this paper, we investigate the physical influences that determin
We report a method using in situ etching to decouple the axial from the radial nanowire growth pathway, independent of other growth parameters. Thereby a wide range of growth parameters can be explored to improve the nanowire properties without concern of tapering or excess structural defects formed during radial growth. We demonstrate the method using etching by HCl during InP nanowire growth. Th
