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Learning from Real Fire Incidents : a Methodology for Case Studies

Much information has been gathered through the years from fires in fire investigation reports or as statistics. The information might have been collected centrally by an agency, an insurance company or locally by the local fire service. The information can be used to learn from these events and to improve the fire safety in buildings. In this paper a methodology to find technical deficiencies in f

Insights Into Protein Synthesis - Structural Aspects of Elongation Factor G and Fusidic Acid Inhibition

Elongation factor G (EF-G) catalyses the translocation step in protein synthesis on the ribosome. During this event the antibiotic Fusidic acid (FA) binds to and irreversably inhibits the release of the EF-G:GDP complex from the ribosome. The difficulties to elucidate the exact binding mechanism of FA to the EF-G:GDP:ribosome complex are due to the fact that FA only binds to EF-G when the factor i

Investigation of turbulence models applied to premixed combustion using a level-set flamelet library approach

Most of the common modeling approaches to premixed combustion in engineering applications are either based on the assumption of infinitely fast chemistry or the flamelet assumption with simple chemistry. The level-set flamelet library approach (FLA) has shown great potential in predicting major species and heat release, as well as intermediate and minor species, where more simple models often fail

Functional aspects of cellobiose dehydrogenase Applications for biosensor development

Electrochemcial investigations were conducted for elucidating and understanding the relation between the various electron transfer processes occurring in cellobiose dehydrogenase (CDH) bound to an electrode surface. Substrate inhibition caused by cellobiose was proven to act in competition with the electron transfer to a two-electron acceptor and under a partial inhibition mechanism for the in

Intergenerational Transmission of Human Capital: Is It a One-Way Street?

Studies on the intergenerational transmission of human capital usually assume a one-way spillover from parents to children. But what if children also affect their parents’ human capital? Using exogenous variation in education, arising from a Swedish compulsory schooling reform in the 1950s and 1960s, we address this question by studying the causal effect of children’s schooling on their parents’ l

Social Militarisation and the Power of History. A Study of Scholarly Perspectives

In this book, three historical macro-regions are analysed: East Asia, Southeast Asia and Mesoamerica. By comparing three very different historiographical patterns from the specific point of view of social militarisation, we gain an outsider's perspective that proves to be very illuminating. Due to structural features of the various scholarly arenas the three regions turn out very differently. Some

Development of adenoviral vectors for monitoring telomerase activity in living cells

Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING PÅ SVENSKA Vår arvsmassa finn's lagrad som linjära dubbelsträngade DNA-molekyler, kromosomer, i våra celler. Celler i vävnader och organ förnya's ständigt genom celldelning. Kromosomerna i en cell måste replikera's för att kunna ge upphov till två nya celler. Replikeringsmaskineriet har bara förmågan att arbeta i en riktning läng's meABSTRACT Telomerase activity is a potential molecular marker for cancer and primitive cells in regenerative tissues. The most commonly used method to measure telomerase activity in cells is the telomerase reverse amplification protocol (TRAP) assay, where the protein extracts derived from homogenized cells are analysed. In this thesis we focused on developing a method where telomerase activity co