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Issues in Human GenEthics
Beta-estradiol effect on erythrocyte aggregation--a controlled in vitro study
The purpose of this in vitro study was to assess the effect of 17beta-estradiol on hemorheologic parameters, namely on erythrocyte aggregation and deformability and membrane fluidity.Blood samples from 65 women (aged 57 +/- 4 years) undergoing postmenopausal hormone replacement therapy were obtained and were incubated for 5 min in absence and presence of 17beta-estradiol 10(-5) M. The measured par
From starch to starch microspheres: Factors controlling the microspheres quality
Starch microparticle is a dosage form suitable for encapsulation of protein drugs. The microparticle characteristics can be influential factors for consecutive sustained drug release from the starch matrix and impact its ability to be coated by poly(D,L-lactide-co-glycolide). In this study, six types of starch microparticles were investigated and characterized. Desired qualities of the microsphere
Transport properties of three-terminal ballistic junctions realized by focused ion beam enhanced etching in InGaAs/InP
Three-terminal junction devices are realized in an InGaAs/InP quantum well by focused ion beam (FIB) implantation and selective wet etching. Room temperature electrical measurements show that the fabricated devices exhibit strong nonlinear electrical properties. The results are discussed in terms of ballistic electron transport. It is demonstrated that FIB-enhanced etching processing can be exploi
Axonal outgrowth on nano-imprinted patterns
Nanotechnology has provided methods to fabricate surface patterns with features down to a few rim. If cells or cell processes exhibit contact guidance in response to such small patterns is an interesting question and could be pertinent for many applications. In the present study we investigated if axonal outgrowth was affected by nano-printed patterns in polymethylmethacrylate (PMMA)-covered silic
Thermal transitions of DODAB vesicular dispersions
Two endothermic transitions, at 36 degrees C and 44 degrees C, were observed with differential scanning calorimetry (DSC) upon heating dioctadecyldimethylammonium bromide vesicle dispersions that were equilibrated below 15 degrees C while in samples kept at 25 degrees C there was only the transition at 44 degrees C, which was shown to be the gel to liquid-crystalline transition by H-1-NMR measurem
Constraints on syn-intrusive ca. 1.8 Ga conglomerate deposits associated with the Småland-Värmland Belt, SE Sweden; Pb-Pb zircon evaporation dating of the Malmbäck conglomerate
Zircon geochronology in polymetamorphic gneisses in the Sveconorwegian orogen, SW Sweden: ion microprobe evidence for 1.46-1.42 and 0.98-0.96 Ga reworking
Ion microprobe U-Th-Pb analyses of zircons in variably metamorphosed and veined orthogneisses in the southern part of the parautochthonous Eastern Segment of the Sveconorwegian (1.20-0.90 Ga) orogen, SW Sweden, broadly define two age groups, oscillatory and sector zoned magmatic zircon cores yield 1.70-1.68 Ga while overgrowths, homogeneous crystals, and recrystallized domains in primary zircon yi
Corticosteroid action on choroid plexus: reduction in Na+-K+-ATPase activity, choline transport capacity, and rate of CSF formation
Glucocorticoids have a well-known clinical effect on brain edema and intracranial hypertension, but the mechanism of action is still poorly understood. In the present report the effect of beta-methasone on choroid plexus transport and CSF formation was studied. Following 5 days of daily treatment with betamethasone the CSF production rate in rabbits was reduced by 43% as measured by ventriculo-cis
Long-term consequences on annual earnings of the onset of type I diabetes in young adults. Longitudinal analysis of annual data 1990-2005 for persons born 1949-1970
Helicobacter pylori antibodies and gastric cancer: a gender-related difference
Helicobacter pylori has been proposed as a causative agent of gastric cancer. The aim of this study was to define serum antibodies response against different H. pylori antigens in patients with gastric cancer. Serum samples were collected from 115 Lithuanian patients with non-cardia gastric cancer and 110 age- and sex-matched controls without cancer. Heat-stable, low-molecular-mass, and outer memb
The Applicability of Enzymes in Cellulose Ether Analysis
Six methyl cellulose (MC) samples, one with a IDS Of 1.32 and five with a DS between 1.83 and 1.88, were degraded with five different enzymes or enzyme preparations containing endoglucanases. The main goal was to investigate whether enzymes could be used for determination of heterogeneity of the substituent distribution along the cellulose chain. To obtain information about the heterogeneity it wa
Influence of non-Markovian relaxation processes on self-induced transparency: Memory function theory for optical solitons
The influence of transverse relaxation on the resonance soliton (2 pi hyperbolic-secant pulse) in solids is considered. It is shown that memory effects can be considered in terms of generalized non-Markovian optical Bloch equations. The equations of self-induced transparency with a memory function are presented. Explicit forms for the first-order effects of this relaxation on the frequency shift a
Isolation and characterization of polymorphic microsatellite loci in the field vole, Microtus agrestis, and their cross-utility in the common vole, Microtus arvalis
We developed nine polymorphic microsatellite loci for the field vole, Microtus agrestis. The number of alleles ranged from five to 15 and observed heterozygosities ranged from 0.40 to 1.00. We also tested the microsatellite loci for amplification and polymorphism in the congeneric species Microtus arvalis. Five of the nine loci were successfully analysed in this species. The microsatellite markers
Local perforator flap for reconstruction of deep tissue defects in the elbow area.
On A2-codes including arbiter's attacks
We comment on the work by R. Taylor presented at Euro-Crypt'94 (see this proceedings). We first extend some known results on authentication codes with arbitration to the case when protection against arbiter's attacks is provided. We give lower bounds on the secret key size for each participant and give a construction showing that these bounds are tight. These results improve upon previously known
Reference values for respiratory system impedance by using impulse oscillometry in children aged 2-11 years.
Determination of drug-protein binding using supported liquid membrane extraction under equilibrium conditions
A technique for determination of drug-protein binding based on a membrane extraction technique termed "equilibrium sampling through membrane (ESTM)" is presented. It involves the establishment of an equilibrium between an aqueous buffer and either a blood plasma sample or a matched buffer, both containing the drug. Analysis of the aqueous buffer in the two cases gives the drug-protein binding. The
A water activity control system for enzymatic reactions in organic media
A water activity control system for enzymatic synthesis in organic media, for litre-scale reactors has been constructed. Water activity, a(w), is a key factor when using enzymes in non-conventional media and the optimum value varies for different enzymes. The control system consists of a water activity sensor in the headspace of a jacketed glass reactor (equipped with narrow steel tubes to introdu
