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Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels.

The purpose of this study was to test the hypothesis that glutamate cysteine ligase catalytic subunit (GCLC) promoter polymorphisms are susceptibility factors for type 1 diabetes (T1D), T1D age-at-onset and T1D autoantibodies. T1D patients and control subjects from the Swedish Childhood Diabetes Registry and the Swedish Diabetes Incidence Study registry were genotyped for two GCLC promoter polymor

Variational issues in the homogenization of discrete systems

The main objective of this work is the application of variational concepts to microscopic multiple particle systems (MPS) which are assigned to corresponding points of a macroscopic continuum. Due to this underlying micro-structure it is not sufficient to simulate the macroscopic behavior with pre-assumed (overall) material parameters, or rather constitutive-law-based standard methods. Therefore,

Dynamic Model Based Friction Compensation on the Furuta Pendulum

The Furuta pendulum is used to evaluate a friction compensator based on the dynamic LuGre friction model. The effect of friction compensation is very well illustrated by reduction of limit cycles when stabilising the pendulum. The observer based LuGre friction compensator is compared with classical Coulomb and Stiction compensator schemes. Existing analysis of the LuGre observer is extended to obs