Search results

Popular Abstract in Swedish N-acyletanolaminer (NAE) tillhör en växande grupp av kroppsegna lipider, som påverkar en mängd olika receptorer och jonkanaler. En sådan substans är anandamid, som finns i hjärnan och många andra organ. 1992 visade en grupp forskare att anandamid aktiverar receptorn för ?9-tetrahydrocannabinol (cannabinoidreceptorn) i centrala nervsystemet. Anandamid och andra NAE bildaN-acylethanolamines (NAEs) belong to a growing family of endogenous signalling molecules acting on a variety of receptors and ion channels. In 1992, it was reported that the N-acylethanolamine anandamide is present in the brain and activates the central cannabinoid (CB) receptor. Anandamide and other NAEs are considered to be generated on demand following receptor activation or cell stress. The ti

We found mutations in the gene PQBP1 in 5 of 29 families with nonsyndromic (MRX) and syndromic (MRXS) forms of X-linked mental retardation (XLMR). Clinical features in affected males include mental retardation, microcephaly, short stature, spastic paraplegia and midline defects. PQBP1 has previously been implicated in the pathogenesis of polyglutamine expansion diseases. Our findings link this gen

InAs nanowire wrap-gate transistors have been fabricated in a vertical geometry using matrices of 11×11 nanowires. The fabrication process is based on conventional and scalable technologies that are adopted for the nanowire transistors. A SiN_x layer is used as gate dielectric and a wrap-gate of 80 nm gate length is formed. These transistors show good DC characteristics with drive curren

A tunable external-cavity Littrow diode laser, with an intracavity electro-optical crystal, which combines a large mode-hop-free tuning range with high tuning speeds and high tuning accuracy, has been designed. A mode-hop-free single-mode tuning range of 50 GHz at 793 nm with an output power of 60 mW and tuning speeds of 1.5 GHz/mus is demonstrated. The instantaneous linewidth is smaller than 300

It has been proposed that excessive and uncontrolled proteolytic activity is an important pathogenetic factor for chronic wounds. Identification of molecules that either control or reflect proteolysis in wounds may prove to be useful in determining wound healing activity. In this study wound fluid was sampled under a polyurethane dressing or on hydrophilic glass filters. Multiple chronic wound flu

We report the pressure dependence of the crystal structure of lead tetroxide (P less than or equal to 41.05 GPa, T 298 K) using high-resolution angle-dispersive X-ray powder diffraction. Pb3O4 shows two reversible phase transitions in the measured pressure range. The crystal structures of the modifications identified have in common frameworks of Pb+4O6 octahedra and irregular Pb+2O4+1 respectively

Abstract is not available

Serum-depleted human foetal skin fibroblasts were stimulated by addition of 10% foetal calf serum to proliferate synchronously for at least one cell cycle. This proliferation was suppressed by leukocyte or fibroblast interferon (IF), which prolonged the G1 phase and diminished the rate of DNA synthesis during the S phase in a dose-dependent manner. When used in identical concentration, as judged i

Research findings suggest that in order to clarify the relationship between occupation and health, occupation needs to be framed in several different ways. One facet of occupation is satisfaction with daily occupations, assessed using the Satisfaction with Daily Occupations (SDO) instrument. The purpose was to investigate some of the SDO's psychometric properties when applied on people with persis

Material of the recently described endemic liverwort Plagiochila norvegica was collected from the type locality in Norway and tested against the widespread P. porelloides for differences in isozyme banding patterns. No difference was found at any of 16 putative loci. A limited sample of P. asplenioides, which was included as an outgroup, differed at five loci.

The local well-posedness for a periodic nonlinear dispersive wave equation in compressible elastic rods is established. Blow-up of solutions in finite time is obtained, provided their initial data satisfy certain conditions. (C) 2003 Elsevier Inc. All rights reserved.

Sweden is among those countries in Europe that have the lowest number of organ donors per million population (PMP). Because of the low numbers of actual donors, it is important to identify the total number of potential donors. Thus, a prospective registration of all deceased patients at all intensive care units was introduced in the Southern Healthcare Region of Sweden, which has a population of 1