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Tlx controls proliferation and patterning of lateral telencephalic progenitor domains

We showed previously that the orphan nuclear receptor Tlx is required for the correct establishment of the pallio-subpallial boundary. Loss of Tlx results in a dorsal expansion of ventral markers (e.g., the homeodomain protein GSH2) into the ventralmost pallial region, i.e., the ventral pallium. We also observed a disproportionate reduction in the size of the Tlx mutant lateral ganglionic eminence

Age relations of cardiovascular risk factors in a traditional Melanesian society: the Kitava Study

This study examined cross-sectional age relations of blood pressure, anthropometric indexes, serum lipids, and hemostatic variables in 203 subsistence horticulturists aged 20-86 y in Kitava, Trobriand Islands, Papua New Guinea. The population is characterized by extreme leanness (despite food abundance), low blood pressure, low plasma plasminogen activator inhibitor 1 activity, and rarity of cardi

Toward clinical application of prompt gamma spectroscopy for in vivo monitoring of boron uptake in boron neutron capture therapy

In boron neutron capture therapy (BNCT) the absorbed dose to the tumor cells and healthy tissues depends critically on the boron uptake. Pronounced individual variations in the uptake patterns have been observed for two boron compounds currently used in clinical trials. This implies a high uncertainty in the determination of the boron dose component. Ln the present work a technique known as prompt

Dextran, gelatin, and hydroxyethyl starch do not affect permeability for albumin in cat skeletal muscle

OBJECTIVE: To evaluate the effects of the three commercially available colloid solutions, 6% dextran 70, 6% hydroxyethyl starch (HES) 200/0.5, and 3.5% urea-linked gelatin on permeability for human albumin in a skeletal muscle in vivo model by evaluating their effects on the reflection coefficient for albumin. DESIGN: Controlled laboratory study. SETTING: University research laboratory. SUBJECTS:

Experimental and simulated M-shell nickel spectra in the 14.4-18.0 nm region from magnetic fusion devices

Experimental M-shell nickel spectra in the 14.4-16.5 nm region from the JET tokamak (from both divertor and limiter configurations) and from the reversed field pinch RFX have been simulated. These spectra include lines from five ionization states, namely from K-like N-i9+ to P-like Ni13+ ions. For the JET limiter configuration the spectrum upper wavelength limit was higher (18.0 nm) and lines from

Laxative treatment elevates plasma homocysteine: a study on a population-based Swedish sample of old people

Objectives. Elevated plasma homocysteine might indicate an increased risk of cancer, and cardiovascular and neurological diseases. The homocysteine level depends on the supply of folate and cobalamine, and constipation and/or laxative treatment might compromise this supply. The present study examined the impact of constipation and laxative treatment on the blood levels of homocysteine, folate and

Radial tunnel release. Unpredictable outcome in 37 consecutive cases with a 1-5 year follow-up

37 consecutive patients with radial tunnel syndrome treated by decompression of the posterior interosseous nerve and application of a free fat transplant were retrospectively evaluated 3.5 (1-5) years post-operatively by an independent observer. Substantial pain relief was reported by 13 patients and 15 patients were satisfied with the outcome. 16 of 35 patients returned to their preoperative empl

Underventilerad brand

Combustion of hydrocarbons in under-ventilated conditions has been studied experimentally and simulated with the CFD-code SOFIE. This report covers the experimental study in a 1/3 scale model of the ISO room corner test (ISO) 9705). The CFD-simulation part of the project has been published earlier in a SP-Report 1996:41 “CFD Modelling if under-ventilated Fires” by Heimo Touvinen and presented at t

Chiral recognition of Nα-protected amino acids and derivatives in molecularly imprinted polymers.

Highly crosslinked synthetic polymers, selective for various Nα-protected amino acids and derivatives, were prepared by non-covalent molecular imprinting. Methacrylic acid and ethylene glycol dimethacrylate were copolymerized in the presence of the print molecules, which were subsequently extracted from the polymers. The recognition of the polymers for the print molecules and molecules of similar

Photoelectron spectroscopy study of Ag/Si(111)root 3X root 3 and the effect of additional Ag adatoms

High-resolution core-level spectroscopy has been applied to the Ag/Si(111)root3xroot3 surface. The Si 2p line shape is found to depend critically on the presence of additional Ag adatoms on the surface. A significant broadening caused by the surplus of Ag atoms could be eliminated by careful annealing. The resulting Si 2p spectra are significantly sharper than any published data for this or other

The structure of <1 1 1 > B oriented GaP nanowires

Nanowires of zinc blende crystal structure, grown in the < 111 > B direction usually have a large number of twin plane defects. In order to investigate this phenomenon, we grow GaP nanowires with metal-organic vapor phase epitaxy. By rotating the nanowires in a high resolution transmission electron microscope, we show that the nanowire segments between the twin planes are of octahedral shape and a

Phomol, a new antiinflammatory metabolite from an endophyte of the medicinal plant Erythrina crista-galli

Phomol (1), a novel antibiotic, was isolated from fermentations of a Phomopsis species in the course of a screening of endophytic fungi from the medicinal plant Erythrina crista-galli. For this Argentinean leguminosa anti inflammatory and neuroleptic activities have been described. The compound exhibits antifungal, antibacterial and weak cytotoxic acticity. The anti inflammatory activity was teste

Planar parabolic X-ray refractive lens made of glassy carbon

Experimental results of synchrotron radiation focusing by parabolic planar compound refractive lenses, made of glassy carbon, are presented. The lenses with the curvature radius of 5 and 200 mu m, and with the geometric aperture of 40 and 900 mu m were developed. The number of bi-concave elements in the compound lenses was from 4 to 200. The experiments were performed at the ESRF at the bending ma