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Impact of donor chest radiography on clinical outcome after lung transplantation

BackgroundOrgan donation guidelines recommend a “clear” conventional bedside chest radiograph before lung transplantation despite only moderate accuracy for cardiopulmonary abnormalities.PurposeTo evaluate the influence of donor image interpretation on lung transplantation outcome in recipients by following early and late complications, one-year survival, and to correlate imaging findings and bloo

P-fimbriae trigger mucosal responses to Escherichia coli in the human urinary tract

Uropathogenic Escherichia coli elicit a host response that determines the severity of urinary tract infection (UTI). Specific adherence mechanisms allow the bacteria to initiate this process by targeting epithelial cells in the urinary tract mucosa. Epidemiological studies show a strong association of P-fimbriae with disease severity, suggesting that adherence mediated by these organelles has a di

Urodynamic factors influence the duration of Escherichia coli bacteriuria in deliberately colonized cases

Purpose: We evaluated the influence of urodynamic factors on the establishment of bacteriuria, after deliberate intravesical inoculation with Escherichia coli. Materials and Methods: Nine women and 7 men with recurrent symptomatic urinary tract infections underwent intravesical injection of E. coli 83972. This strain had documented ability to persist in the urinary tract and it lacks expressed vir

Competetive microbial exclusion as treatment against complicated lower urinary tract infections

OBJECTIVE: Deliberate colonization of the lower urinary tract has been proposed as treatment against recurrent urinary tract infection - UTI. The bacteria chosen has to be able to colonize the urinary tract for longer periods without causing symptoms, and should be able to prevent manifest superinfections. MATERIALS: Sixteen patients (9 women and 7 males), all having a history of recurrent symptom

Efficient Merging of Maps and Detection of Changes

With the advent of cheap sensors and computing capabilities as well as better algorithms it is now possible to do structure from motion using crowd sourced data. Individual estimates of a map can be obtained using structure from motion (SfM) or simultaneous localization and mapping (SLAM) using e.g. images, sound or radio. However the problem of map merging as used for collaborative SLAM needs fur

An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia

To define the mutation spectrum in non-Down syndrome acute megakaryoblastic leukemia (non-DS-AMKL), we performed transcriptome sequencing on diagnostic blasts from 14 pediatric patients and validated our findings in a recurrency/validation cohort consisting of 34 pediatric and 28 adult AMKL samples. Our analysis identified a cryptic chromosome 16 inversion (inv(16)(p13.3q24.3)) in 27% of pediatric

Identification of modifications procuring growth on xylose in recombinant Saccharomyces cerevisiae strains carrying the Weimberg pathway

The most prevalent xylose-assimilating pathways in recombinant Saccharomyces cerevisiae, i.e. the xylose isomerase (XI) and the xylose reductase/xylitol dehydrogenase (XR/XDH) pathways, channel the carbon flux through the pentose phosphate pathway and further into glycolysis. In contrast, the oxidative and non-phosphorylative bacterial Weimberg pathway channels the xylose carbon through five steps

Parametric Model-Based 3D Human Shape and Pose Estimation from Multiple Views

Human body pose and shape estimation is an important and challenging task in computer vision. This paper presents a novel method for estimating 3D human body pose and shape from several RGB images, using detected joint positions in the images and based on a parametric human body model. Firstly, the 2D joint points of the RGB images are estimated using a deep neural network, which provides a strong

Progressive striatonigral degeneration in a transgenic mouse model of multiple system atrophy : translational implications for interventional therapies

Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disorder characterized by widespread oligodendroglial cytoplasmic inclusions of filamentous α-synuclein, and neuronal loss in autonomic centres, basal ganglia and cerebellar circuits. It has been suggested that primary oligodendroglial α-synucleinopathy may represent a trigger in the pathogenesis of MSA, but the mechanisms un

On Robustness of Equilibria in Dynamical Transportation Networks

With growing traffic demands, transportation networks become more and more congested and prone to disruptions. In this paper, we study how different perturbations affect the free flow equilibria, i.e., equilibria where no congestion effects are present, in transportation networks. More specifically, if and when the equilibrium of the perturbed dynamics is still in free flow. A generalized cell tra

Disturbance of the bacterial communities in drinking water produced from established and newly-built slow sand filters

IntroductionSlow sand filtration is an established method for drinking water treatment, however, the knowledge about their microbial ecology remains limited. Maintenance of slow sand filters (SSF) includes washing to remove biofilm growth in the sand and restore flow through the filter. Understanding how this impacts produced water is important as the SSF may influence the bacterial flora in the f