Mitochondrial reactive oxygen species (ROS) are implicated in signal transduction, inflammation, neurodegenerative disorders, and normal aging. Net ROS release by isolated brain mitochondria derived from a mixture of neurons and glia is readily quantified using fluorescent dyes. Measuring intracellular ROS in intact neurons or glia and assigning the origin to mitochondria are far more difficult. I

In 1987 we noticed excess adipose tissue in a patient with arm lymphedema and later, objective studies confirmed this clinical finding in patients with non-pitting arm lymphedema following breast cancer. A prospective study was begun in 1993, and its long-term results (15 years) shows overall complete reduction of the excess volume in patients with non-pitting arm lymphedema and that adipose tissu

Configuration management (CM) includes synchronizing and supporting developers in their common development and maintenance of a system. The rapid development of the Internet and time-to-market pressure affects software development. In order to utilize skilled personnel despite geographical location, groups of developers are now working all over the world on the development of common systems, a sit

BACKGROUND: Previously, small studies have found that BRCA1 and BRCA2 breast tumors differ in their pathology. Analysis of larger datasets of mutation carriers should allow further tumor characterization.METHODS: We used data from 4,325 BRCA1 and 2,568 BRCA2 mutation carriers to analyze the pathology of invasive breast, ovarian, and contralateral breast cancers.RESULTS: There was strong evidence t

Measurements of the radiation from a dipole lambda/2-dipole antenna inside a common car was compared to calculations at 1.9 GHz, to establish a principal knowledge of the radiation mechanism related to a vehicle such as a car. Based on this a new simple directional path loss model is proposed, that uses minimal knowledge of the vehicle's geometry. This model may be well suited for simulations of m

BACKGROUND: Animal studies suggest that the arginine vasopressin system may play a role in glucose metabolism, but data from humans are limited. METHODS AND RESULTS: We analyzed plasma copeptin (copeptin), a stable C-terminal fragment of the arginine vasopressin prohormone. Using baseline and longitudinal data from a Swedish population-based sample (n=4742; mean age, 58 years; 60% women) and multi

Components derived from cartilage have been suggested to maintain the inflammation in joints in arthritis. Small leucine-rich repeat proteins (SLRPs) are structural components of cartilage important in organizing the meshwork of extracellular matrix components. It has recently been shown that the SLRP fibromodulin interacts with complement initiator C1q, leading to complement activation. The compl

Artikeln diskuterar hur begreppen livsstil och livsföring introducerades i sociologin. Bland annat visas på att begreppet livsstil intorducerades på bred front av Simmel i "Philosophie des Geldes" (1900). Avslutningsvis diskuteras några möjliga användningar av begreppen idag.

A summary of different risk analysis methods for building fire safety is presented. The methods are: the Gretener system, GSA concept tree, NFPA methods and the Danish ARGOS system.

A report from the conference Post-Colonialism and Global Migration and the exhibition Inclusion/Exclusion held in Graz, Austria, in 1997.

Background: To date, no attempt has been made to systematically determine the apportionment of the hepatocellular carcinoma burden in Europe or North America among established risk factors.MethodsUsing data collected from 1992 to 2006, which included 4 409 809 person-years in the European Prospective Investigation into Cancer and nutrition (EPIC), we identified 125 case patients with hepatocellula

IT procurement represents a business process of high importance, including the ability to articulate requirements that the procurement deals with. Furthermore, specifying requirements is of importance for both procurer and potential supplier, as it functions as central contractual element between the two. The purpose of this article is two-fold: (i) to show how established terminology for requirem

Snowmelt and runoff in urban areas in Lulea, north Sweden, are discussed and compared with rural conditions. The uneven snow distribution in cities is quantified. Energy fluxes at the snow surface in different environments are estimated. It is shown that, mainly because of increased absorbed radiative energy in the snow, the daily melt is about 10 mm higher in the city than in rural environments.

In this paper linearity of frequency modulation in voltage controlled inverter ring oscillators for non feedback sigma delta converter applications is studied. The linearity is studied through theoretical models of the oscillator operating at supply voltages above and below the threshold voltage of a transistor, bringing the transistors in respectively strong and weak inversion. The theoretical re

The purpose of this study was to verify and validate a noise simulation tool called Dose Tutor (VAMP GmbH) in terms of level and texture of the simulated noise. By adding artificial noise to measured computed tomography (CT) raw data, a scan acquired with a lower dose (mAs) than the actual one can be simulated. A homogeneous polyethylene phantom and an anthropomorphic chest phantom were scanned fo

Kulturartikel om Fritz Langs stumfilm Metropolis med anledning av en nästan komplett restaurering och utgåva på dvd och bluray.