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Book Reviews 2015

This section contains three book reviews. First the book Swedish Taxation, Development since 1862 is reviewed. This volume comprises six studies that examine the development of Swedish taxation from 1862 to 2013, and will likely be of great value in future Nordic tax research because of its comprehensiveness. The second review is about a book written in Swedish:Momsfri sjukvård (The VAT exemption

A Low-complexity Channel Shortening Receiver with Diversity Support for Evolved 2G Devices

The second generation (2G) cellular networks are the current workhorse for machine-to-machine (M2M) communications. Diversity in 2G devices can be present both in form of multiple receive branches and blind repetitions. In presence of diversity, intersymbol interference (ISI) equalization and co-channel interference (CCI) suppression are usually very complex. In this paper, we consider the improve

Applying landscape genetics to the microbial world

Landscape genetics, which explicitly quantifies landscape effects on gene flow and adaptation, has largely focused on macroorganisms, with little attention given to microor- ganisms. This is despite overwhelming evidence that microorganisms exhibit spatial genetic structuring in rela- tion to environmental variables. The increasing accessi- bility of genomic data has opened up the opportunity for

The Impact of Classroom Practices on Young Learners' Acquisition of Subject-Verb Agreement in Vietnam : a Pilot Study

Researchers have long emphasized the importance of classroominteraction for enhancing foreign language learning (Carroll 1967; Chihara& Oller, 1987; Krashen, Butler, Birkbaum, & Robertson 1978; Krashen &Seliger, 1976). This pilot study attempts to see how English teaching and learning methods in Vietnamese classrooms affect young learners’acquisition of English subject-verb agreement i

Older People Meet Robots : Three Case Studies on the Domestication of Robots in Everyday Life

This thesis explores how older people construct meaning, use and make sense of three kinds of robots in their homes. The exploration is undertaken in empirical studies of an assistive robot, an eHealth system, and robotic vacuum cleaners. The research draws on data collected through interviews and observations of older people in relation to three robots. The results show that older people’s domest

Simultaneous targeted activation of Notch1 and Vhl-disruption in the kidney proximal epithelial tubular cells in mice

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer, representing approximately 75% of all renal neoplasms. ccRCC is known to be strongly associated with silencing of the von Hippel Lindau (VHL) tumor suppressor gene, yet VHL deficiency alone does not seem to be sufficient to drive the oncogenic transformation of normal renal epithelium and induce renal tumorigenesi

Abolished angiogenicity and tumorigenicity of Burkitt lymphoma by interleukin-10

Because of its immunosuppressive properties, interleukin-10 (IL-10) is thought to play an important role in a number of human disease states, including inflammation, autoimmunity, and transplant rejection. In this study, we demonstrate that introduction of human or viral IL-10 genes into Burkitt's lymphoma cells markedly reduced their ability to grow as subcutaneous (sc) tumors in SCID mice. In vi

Selection of antibodies for intracellular function using a two-hybrid in vivo system

Expression of antibodies inside cells has been used successfully to ablate protein function. This finding suggests that the technology should have an impact on disease treatment and in functional genomics where proteins of unknown function are predicted from genomic sequences. A major hindrance is the paucity of antibodies that function in eukaryotic cells, presumably because the antibodies fold i

Time and the Writers

Etzel Cardeña and Lauren Reid investigate how literature can open up different models of thinking about time. These models of time are brought to life by clips from the spectacular films of the one-and-only director and choreographer - Busby Berkeley.

LIM-only protein Lmo2 forms a protein complex with erythroid transcription factor GATA-1

The LIM-only protein Lmo2, originally identified as an oncogenic protein in human T cell leukemia, is essential for erythropoiesis. A possible role for Lmo2 in transcription during erythropoiesis has been investigated. Direct interaction of Lmo2 was observed in vitro and in vivo with the zinc finger transcription factor GATA-1, as well as with the basic helix-loop-helix (bHLH) transcription factor

Association of erythroid transcription factors : complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1

The RBTN2 LIM-domain protein, originally identified as an oncogenic protein in human T-cell leukemia, is essential for erythropoiesis. A possible role for RBTN2 in transcription during erythropoiesis has been investigated. Direct interaction of the RBTN2 protein was observed in vivo and in vitro with the GATA1 or -2 zinc-finger transcription factors, as well as with the basic helix-loop-helix prot

Chromosomal translocations and leukaemia : a role for LMO2 in T cell acute leukaemia, in transcription and in erythropoiesis

The LMO2 gene associated with T cell acute leukaemia has been used as an example of a gene activated by association with the T cell receptor genes after chromosomal translocations. The gene is shown to encode a LIM protein which is involved in protein interactions and during normal haematopoiesis is necessary for erythroid development. LMO2 has been shown to cause tumours when aberrantly expressed

Functional diversity of LIM proteins : amino-terminal activation domains in the oncogenic proteins RBTN1 and RBTN2

The RBTN1 and RBTN2 genes are activated by distinct translocations involving chromosome 11 in some T cell acute leukaemias. The RBTN proteins belong to the LIM family which comprises proteins with one, two or three cysteine-rich LIM domains, sometimes together with homeodomains or protein kinase domains. The RBTN1 and RBTN2 proteins comprise only tandem LIM domains. We report that RBTN1 and RBTN2