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The complement system is a proteolytic cascade triggered by pathogen and danger-associated molecular patterns, with resultant outcomes of inflammation, cellular activation, and opsonization of material for removal by phagocytosis. While first discovered as an activity in serum, it is now recognized that complement components play important roles at local and individual cell-intrinsic levels. In pa
Decisions made by millions of refugees about where to go, how to make a living and how to secure a future are fundamental drivers of secondary movements. While a substantial body of literature addresses factors contributing to migrants’ decision-making, a comprehensive understanding of the central role of refugees in secondary mobility decision-making, including agency and strategies employed, rem
Purpose: Fluid-structure interaction (FSI) models are more commonly applied in medical research as computational power is increasing. However, understanding the accuracy of FSI models is crucial, especially in the context of heart valve disease in patient-specific models. Therefore, this study aimed to create a multi-modal benchmarking data set for cardiac-inspired FSI models, based on clinically
Personer med synnedsättningar behöver ljushetskontraster för att varnas, för att få ledning och för att hitta. Kunskapen är emellertid dålig vad gäller utformningsdetaljer. Denna studie skall ligga till grund för förbättring av råden om utformning för bättre orienteringsmöjligheter för personer med synnedsättningar bl.a. vid revidering av Vägverkets och Svenska Kommunförbundets handbok Vägars och
För att personer som är blinda ska kunna orientera sig i den byggda miljön behövs sammanhängande ledstråk som går att följa från start- till målpunkt. Rapporten redovisar en studie av hur ett sammanhängande ledstråk fungerar för personer som är blinda. Ledstråken består av naturliga och konstgjorda ledytor och varningsytor och valytor. Studien kommer att ligga till grund för förbättring av kraven
Trafikverket har ansvar för att förverkliga den beslutade funktionshinderspolitiken, som regleras i regeringsuppdrag och i en särskild förordning, SFS 2014:135. Trafikverket ska vara ett föredöme när det gäller tillgänglighet för personer med funktionsnedsättning, och bidra till allas delaktighet i samhället. Syftet med den föreliggande kunskapssammanställningen är att samla den kunskap som finns
Progressive myoclonus ataxia (PMA) is a rare clinical syndrome characterized by the presence of progressive myoclonus and ataxia, and can be accompanied by mild cognitive impairment and infrequent epileptic seizures. This is the first study to describe the natural history of PMA and identify clinical, electrophysiological, and genetic features explaining the variability in disease progression. A D
German-Jewish historian and folklorist Abraham Tendlau published this feuilleton in a supplement to “Der Israelit”, an orthodox newspaper based in Mainz. It includes summaries and long quotations (combining transliteration and translation) of the Yiddish-language “diary” of Glikl bas Judah Leib, whose writing appears here for the first time in print.
Translation from Yiddish with Introduction.
Microbial, algal, plant and animal cells have been immobilized, with preserved viability, by entrapment in various matrices according to a new bead polymerization technique. The cell polymer/monomer mixture is kept suspended in a hydrophobic phase such as soy, paraffin, or silicon oil, tri-n-butylphosphate, or dibutyphtalate, which is compatible with the cells. The various monomers or polymers tes
Horse liver alcohol dehydrogenase was immobilized on glycerylpropyl-silica (10 μm, 1000-Å pores) activated with 2,2,2-trifluoroethanesulfonyl chloride (tresyl chloride). The coupling and activity yield was almost 100%. The coenzyme-binding sites were equivalent and virtually unaffected by the immobilization process, as judged from Scatchard plots and active-site titrations. The silica-bound enzyme
This is an explorative and, at times, tentative text on the potential meanings and uses of the concept Existential Sustainability in social work and social work research. The overall argument is that to create a positive change in the lives of people in general, service users more specifically, and to sustain such change over time, it is necessary to acknowledge an existential dimension and existeThis is an explorative and, at times, tentative text on the potential meanings and uses of the concept Existential Sustainability in social work and social work research. The overall argument is that to create a positive change in the lives of people in general, service users more specifically, and to sustain such change over time, it is necessary to acknowledge an existential dimension and existe
