Objective. To analyse how the main components of the disease phenotype (sicca symptoms, diagnostic tests, immunological markers and systemic disease) can be driven by the age at diagnosis of primary Sjögren's syndrome (pSS). Methods. By January 2021, the participant centres had included 12,753 patients from 25 countries that fulfilled the 2002/2016 classification criteria for pSS. The age at diagn

Many jurisdictions have broadened the scope of criminalized sexual violence through the introduction of consent-based models. At the same time, measures have been taken in regards to the subjective elements for criminal liability in answer to a common defence in rape cases: namely, that the defendant lacked knowledge of the other person’s lack of consent. While some jurisdictions have introduced l

Aim: Identifying how climate change, habitat loss, and corridors interact to influence species survival or extinction is critical to understanding macro-scale biodiversity dynamics under changing environments. In North America, the ice-free corridor was the only major pathway for northward migration by megafaunal species during the last deglaciation. However, the timing and interplay among the lat

Sustainability of the enterprise is crucial to support long-term business survival and development. Unpredictable events such as Covid-19 highlights sustainability issues in enterprises. This empirical study aims to investigate sociotechnical sustainability in real world work practices. The focus is on employee involvement and problems in work practices concerning the economic, environmental, soci

The paracingulate sulcus is a tertiary sulcus formed during the third trimester. In healthy individuals paracingulate sulcation is more prevalent in the left hemisphere. The anterior cingulate and paracingulate gyri are focal points of neurodegeneration in behavioral variant frontotemporal dementia (bvFTD). This study aims to determine the prevalence and impact of paracingulate sulcation in bvFTD.

INTRODUCTION: Many patients with cognitive and neuropsychiatric symptoms face diagnostic delay and misdiagnosis. We investigated whether cerebrospinal fluid (CSF) neurofilament light (NfL) and total-tau (t-tau) could assist in the clinical scenario of differentiating neurodegenerative (ND) from psychiatric disorders (PSY), and rapidly progressive disorders.METHODS: Biomarkers were examined in pati

Swetra is primarily a research project, but its computer programs and reports may result in commercial products. The research group at Lund consists of a few persons only, which has advantages eind disadvantages. The main languages studied are Russian, English and Swedish. The grammatical model is Referent Grammar (RG) and the project is a spin-off of the development of that grammar. Referent Gram

The lack of methods to evaluate mechanical function of donated hearts in the context of transplantation imposes large precautionary margins, translating into a low utilization rate of donor organs. This has spawned research into cyber-physical models constituting artificial afterloads (arterial trees), that can serve to evaluate the contractile capacity of the donor heart. The Windkessel model is

The 400-km long coast of the Bight of Benin, formed by sand barriers and lagoons, is bordered to the east by the Niger River Delta and to the west by the Volta River Delta and is characterized by several coastal infrastructures, of which the most important are the deep water harbors of Lomé, Cotonou, and Lagos. In this study, an enhanced version of the CASCADE coastal evolution model was implement

Biografisk artikel om skådespelerskan och revyprimadonnan Nita Hårleman (1891-1961).

Nanocomposites, formed by incorporating nanoparticles into a matrix of standard materials, are increasing on the market. Little focus has been directed towards safe disposal and recycling of these new materials even though the disposal has been identified as a phase of the products' life cycle with a high risk of uncontrolled emissions of nanomaterials. In this study, we investigate if the carbon

The ultrafast structural dynamics of water following inner-shell ionization is a crucial issue in high-energy radiation chemistry. We have exposed isolated water molecules to a short X-ray pulse from a free-electron laser and detected momenta of all produced ions in coincidence. By combining experimental results and theoretical modeling, we can image dissociation dynamics of individual molecules i