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Placental malaria infection is mediated by the binding of the malarial VAR2CSA protein to the placental glycosaminoglycan, chondroitin sulfate. Recombinant subfragments of VAR2CSA (rVAR2) have also been shown to bind specifically and with high affinity to cancer cells and tissues, suggesting the presence of a shared type of oncofetal chondroitin sulfate (ofCS) in the placenta and in tumors. Howeve

Background and aims: PPARGC1A encodes PGC-1α (peroxisome proliferator-activated receptor γ coactivator 1-α), a central regulator of energy metabolism and mitochondrial function. A common polymorphism in PPARGC1A (rs8192678, C/T, Gly482Ser) has been associated with obesity and related metabolic disorders, but no published functional studies have investigated direct allele-specific effects in adipoc

BACKGROUND: Diesel engine exhaust causes adverse health effects. Meanwhile, the impact of renewable diesel exhaust, such as hydrotreated vegetable oil (HVO), on human health is less known. Nineteen healthy volunteers were exposed to HVO exhaust for 3 h in a chamber with a double-blind, randomized setup. Exposure scenarios comprised of HVO exhaust from two modern non-road vehicles with 1) no aftert

This article aims to provide a systemic instrument to evaluate the functioning of higher education systems. Despite systemic instruments have had a strong impact on the management of public policy systems in fields such as health and innovation, higher education has not been widely discussed in applying this type of instrument. Herein lies the main gap that we want to close. The ultimate purpose o

Objectives: This study aimed to describe the clinical experience of the health-care professionals (HCPs) responsible for the introduction of methadone, for the treatment of complex cancer pain, at a low-resource hospital in India in a patient-group, burdened by illiteracy, and low socio-economic status. Materials and Methods: Ten HCPs: Four medical doctors, four nurses, one pharmacist, and one hos

The Swedish Neutron Scattering Society (SNSS) is an organization open to all those associated with Sweden who are using, or interested in the use of, neutron scattering techniques. Currently, the SNSS has around 230 members distributed all over Sweden. The SNSS is a member of the European Neutron Scattering Association (ENSA) [1], which represents the majority of the national neutron scattering so

Objective: To develop a simple and effective risk score for predicting which stroke patients will have persistent impairment of upper extremity motor function at 90 days. Design: Post hoc analysis of clinical trial patients hospitalized with acute ischemic stroke who were followed for 90 days to determine functional outcome. Setting: Patient were hospitalized at facilities across the United States

With the increased demand for controlled deterministic growth of III–V semiconductors at the nanoscale, the impact and interest of understanding defect formation and crystal structure switching becomes increasingly important. Vapor–liquid–solid (VLS) growth of semiconductor nanocrystals is an important mechanism for controlling and studying the formation of individual crystal layers and stacking d

Abstract in GermanIm Artikel wird eine Untersuchung zur Übersetzung satzwertiger Partizipialkonstruktionen vom Deutschen ins Schwedische präsentiert. Es geht um unflektierte Partizipialphrasen wie in München angekommen (mit dem Partizip Perfekt) bzw. gegen den Wind kämpfend (mit dem Partizip Präsens).Auch wenn sich ein propositionaler Inhalt in beiden Sprachen sowohl durch einen vollständigen Satz

A capacitive biosensor for the detection of protein A was developed. Gold electrodes were fabricated by thermal evaporation and patterned by photoresist photolithography. A layer-by-layer (LbL) assembly of thiourea (TU) and HAuCl4 and chemical reduction was utilized to prepare a probe with a different number of layers of TU and gold nanoparticles (AuNPs). The LbL-modified electrodes were used for

Hyperspectral lidar (HSL) is a novel remote sensing technology that provides spectral information in addition to spatial features. This unprecedented data source leads to new possibilities for monitoring leaf biochemistry. Inversion of physically based radiative transfer models (RTMs) is a popular method for deriving leaf physiological traits due to its robustness and generalization capability. Ho

We provide the first dedicated laboratory study of collisions of supercooled water drops with ice particles as a secondary ice production mechanism. We experimentally investigated collisions of supercooled water drops (∼5 mm in diameter) with ice particles of a similar size (∼6 mm in diameter) placed on a glass slide at temperatures >-12 °C. Our results showed that secondary drops were generated d

There is increasing empirical support for the biodiversity and ecosystem service (ES) benefits of mixed-species production forests. However, few studies control for the spatial arrangement of the trees within mixtures to determine the influence that clustering the tree species (patch scale mixtures), versus evenly dispersing them (intimate scale mixtures), may have for biodiversity and ES outcomes

Background: Previous studies have demonstrated that low-grade red blood cell transfusions (RBC) given to septic patients are harmful. The objectives of the present study were to compare mortality and morbidity in non-septic critically ill patients who were given low-grade RBC transfusions at haemoglobin level > 70 g L–1 with patients without RBC-transfusions any of the first 5 days in intensive ca