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Aetiology and antibiotic susceptibility of bacterial keratitis at a referral centre in southern Sweden

This was a retrospective cross-sectional study evaluating the aetiology and antibiotic susceptibility in patients treated for suspected bacterial keratitis at Skåne University Hospital during 2019. Inclusion criteria: eyes with bacterial keratitis. Exclusion criteria: co-infection with other microbes. Primary outcome parameters: predisposing factors, causative pathogens and antibiotic susceptibili

Excellent prospects : Arguing ‘value-added’ in research excellence proposals

Research excellence instruments (REIs) are among the most popular types of research funding in several research systems, including the Global South. A significant proportion of REIs is intended to promote pathbreaking or groundbreaking contributions. Specific research outcomes can often be traced back to a given project’s scientific objectives, but projections about the impact on the field and the

Attempted suicide short intervention program for older adults 65+ (ASSIP-OA) : a study protocol for a multicentre randomised controlled trial

Background: Older adults are underrepresented in suicide prevention research, even though suicide rates are higher in this age group (65+) than in any other age group in many countries worldwide. There are few clinical intervention studies that target this age group. A promising preventive intervention is the Attempted Suicide Short Intervention Program (ASSIP). Given differences in suicidal behav

Next generation multi-element monolithic Germanium detectors for spectroscopy : First integration at ESRF facility

The XAFS-DET work package of the European LEAPS-INNOV project is developing high-purity Germanium detectors for synchrotron applications requiring spectroscopic-grade response. The detectors integrate three key features: (1) newly designed monolithic Germanium sensors optimized to mitigate charge-sharing events, (2) an improved cooling and mechanical design structure supported by thermal simulatio

Gene sco1417 encodes a positive regulator of the de novo biosynthesis of pyridoxal 5ʹ-phosphate (vitamin B6) in Streptomyces coelicolor M145

Background: Actinomycetes of the genus Streptomyces are renowned for their highly developed and diverse specialized metaboliс pathways, and there is an extensive body of data on their specific and pleiotropic levels of regulation. Much less is known about routes leading to essential metabolites in this genus. In this work, we focused on elucidating the function of the highly conserved across Strep

“When You Feel Like There is No Trust in the Profession” : Midwives and Obstetricians Facing Complicated Cases

This study examines how two collaborating professions, midwifery and obstetrics, are influenced by women requesting caesarean sections. The empirical material consists of semi-structured interviews with Swedish midwives (n=6) and obstetricians (n=6). Analysed through Tilly’s terms, the categorical pair and triad, midwife and obstetrician function as complementary categories in a triad with the wom

Real-Time Brain-Computer Interfaces

A brain-computer interface (BCI) is a real-time system that converts a user’s brain activity into commands, enabling control over applications such as moving a cursor on the screen. This conversion is made possible by machine learning techniques and other algorithms. Historically, BCI research has focused on the analysis of brain signals offline. However, increasing computational power and algorit

Migrant welfare recipients managing their own scarce resources and those of others : a case of food uncertainty

Considering increasing living costs and lagging compensation levels in the welfare system, people on social welfare have difficulties accessing food to the extent needed. This presentation is based on a Swedish study aimed to reveal how migrant welfare recipients act, react, and reason in their management of their own scarce resources and those of others. Striving for ‘dignity’ took a prominent pl

Galactic Disc Dynamics and Structure : Analysis of the Phase Spiral and Vertical Scale-heights

The Milky Way provides the most detailed laboratory we have access to for studying the processes of galaxy formation and evolution. Modern large-scale surveys, most notably the Gaia mission, have revolutionised this field by revealing the extent to which the Galaxy is not a steady system, but dynamically active and rich in non-equilibrium features that preserve traces of past interactions. Underst

Awareness of how I am and how I want to be when communicating with people in need of care - Nursing students' experiences of theoretical and practical training in person-centred communication

AIM: To explore nursing students' experiences of what they had learned and gained through participating in simulation-based communication training anchored in person-centred values.BACKGROUND: Person-centredness is a core component of nurses' work and an important part of it is person-centred communication. To promote patients' wellbeing and comfort, nursing students must become prepared during th

Introduction: Gender, Archiving, and Knowledge Production after the Holocaust : A Postwar Republic of Letters?

The fourth issue of the yearbook History of Intellectual Culture (HIC) features a thematic section on the production of knowledge related to the Holocaust. The contributions focus on the circulation of knowledge via letters and other forms of written communication within and among survivor historical commissions after the Second World War with an emphasis on the interplay of gender and other diffe

Loss and damage in fisheries : Building on fishers’ situated knowledge to inform ways of knowing

Loss and damage in fisheries is acknowledged in climate change policy and science but is both undefined and contested, and there is a lack of empirical exploration of the topic. This paper presents the first in-depth, empirical analysis of how fishers’ situated knowledge of socio-ecological changes can inform our understanding of loss and damage in fisheries. The paper conducts a case study from M

Structural characterization of an extracellular contractile injection system from Photorhabdus luminescens in extended and contracted states

Contractile injection systems (CISs) are phage tail-like nanosyringes that mediate bacterial interactions by puncturing target cell membranes. Within these systems, Photorhabdus Virulence Cassettes (PVCs) can translocate toxins across eukaryotic target cell membranes and have been engineered to deliver diverse protein cargoes into non-natively-targeted organisms. Despite the structural insights in

Den revolterande eliten eller den kreativa klassen? : Christopher Lasch, Richard Florida och det amerikanska presidentvalet 2024

Aims The Trump movement displays several key features of a populist movement with a strong leader and a broad unorganized base of followers opposed to a per-ceived liberal elite establishment. In 2024, Trump gained strong support from strata with low income, low education and Hispanic men, previously not strong support-ers of Republicans. This study investigates the preconditions for a populist moAims The Trump movement displays several key features of a populist movement with a strong leader and a broad unorganized base of followers opposed to a per-ceived liberal elite establishment. In 2024, Trump gained strong support from strata with low income, low education and Hispanic men, previously not strong support-ers of Republicans. This study investigates the preconditions for a populist mo

Distribution of mental health diagnoses in relation to sexual orientation and gender discontent in a late adolescent community population

BACKGROUND: Few population studies have assessed the prevalence of various psychiatric disorders separately for sexual and gender minority groups, and none in an adolescent population. Given the increased mental health problems in sexual and gender minority groups combined, the present study aimed to estimate prevalence of mental disorders in separate sexual minority groups as well as gender disco

Rationale and design of a registry-based randomized controlled study of personalized biomarker-based risk score-guided stroke prevention treatment in atrial fibrillation

Background: Stroke and reduced survival are devastating complications of atrial fibrillation (AF). Biomarker-based ABC-AF risk scores improve risk prediction in AF, and risk-guided treatment recommendations may improve patient outcomes. Design: The ABC-AF study is a national, multicenter, prospective, registry-based, randomized controlled, parallel-group, open-label study. Its primary objective is

Prevalence of Sexual and Gender Minorities in a Swedish Adolescent Community Population : Stability vs. Fluidity of Sexual Orientation

This study examined the prevalence, stability, and fluidity of sexual orientation as well as the prevalence of gender discontent. From a community sample (i.e., all adolescents of the age cohort were invited), this study analyzed data from 1513 adolescents (50.5% females), who replied to questions about sexual attraction on at least one of three occasions (age 14: n = 623; age 15: n = 1322; and ag

Understanding the role of obesity in endocrine therapy for postmenopausal breast cancer : significance of the BIG 1–98 and ATAC trial data

Obesity is a known risk factor for poor breast cancer outcomes, but its impact on endocrine therapy efficacy remains unclear. While the ATAC trial suggests reduced effectiveness of aromatase inhibitors (AIs) in women with obesity, the BIG 1–98 trial found no significant differences. Clinical and biological evidence indicates that obesity may impair AI efficacy by increasing aromatase activity and

Engineering bimetallic CuAu to suppress hydrogen evolution and enhance charge transfer for improved photoelectrochemical nitrogen reduction

Green ammonia synthesis from nitrogen via photocatalysis and electrocatalysis has emerged as a pivotal research focus in sustainable chemical processes. The efficient catalytic reduction of nitrogen necessitates concurrent nitrogen activation and hydrogen evolution suppression, representing a significant challenge. In this study, CuAu bimetallic-modified TiO2 catalysts were developed and engineere

Transplacental sirolimus : a new treatment strategy for life-threatening fetal cardiac rhabdomyomas—a case report

Large cardiac rhabdomyomas can disturb hemodynamic flow. Tuberous sclerosis complex is the most common cause of cardiac rhabdomyoma in fetuses. Recently, a mammalian target of rapamycin (mTOR) inhibitor effectively treated rhabdomyomas associated with tuberous sclerosis. Here, we report the effectiveness of an mTOR inhibitor in treating a fetus with large rhabdomyomas exhibiting severe heart failu