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Surface guided electron FLASH radiotherapy for canine cancer patients

BackgroundDuring recent years FLASH radiotherapy (FLASH-RT) has shown promising results in radiation oncology, with the potential to spare normal tissue while maintaining the antitumor effects. The high speed of the FLASH-RT delivery increases the need for fast and precise motion monitoring to avoid underdosing the target. Surface guided radiotherapy (SGRT) uses surface imaging (SI) to render a 3D

LuMaMi28 : Real-Time Millimeter-Wave Multi-User MIMO Systems with Antenna Selection

This paper presents LuMaMi28, a real-time 28GHz multi-user (MU) multiple-input multiple-output (MIMO) testbed. In this testbed, the base station has 16 transceiver chains with a fully-digital beamforming architecture (with different pre-coding algorithms) and simultaneously supports multiple user equipments (UEs) with spatial multiplexing. The UEs are equipped with a beam-switchable antenna array

Caveolin-1 genotypes as predictor for locoregional recurrence and contralateral disease in breast cancer

Purpose: Caveolin-1 (CAV1) has been implicated in breast cancer oncogenesis and metastasis and may be a potential prognosticator, especially for non-distant events. CAV1 functions as a master regulator of membrane transport and cell signaling. Several CAV1 SNPs have been linked to multiple cancers, but the prognostic impact of CAV1 SNPs in breast cancer remains unclear. Here, we investigated CAV1

Spherical White with Diamond

Site-specific public work, commissioned by NATUR North Atlantic Tales/Curated Place in collaboration with National Trust Formby. The work includes three sound installations: 'Spherical White with Diamond', stereo work (voice: Jez Dolan). 'Þytur', 9 mono-channels (voices: Maja Jantar, Angela Rawlings, Halla Steinunn Stefánsdóttir). 'The Shadowy Space Beneath', a stereo work, which builds on texts f

Image Processing

Image processing provides tools for image enhancement and extraction of information from images. Modification of the colour table allows for amplification of the contrast in certain pixel-value intervals while the contrast is suppressed in other intervals. This can in turn be used to selectively enhance the displayed image in intervals of special importance to the current problem. One of the most

Extrusion of high-moisture meat analogues from hempseed protein concentrate and oat fibre residue

Hempseed protein concentrate (HPC) was extracted from hempseed press cake with a protein content of 85.7% and co-extruded with oat fibre residue (OFR) to produce high-moisture meat analogues (HMMA) at different moisture contents (60, 63, 66%), screw speeds (500, 700, 900) and temperature profiles (40-70-110-130 °C and 40-70-120-150 °C). The effect of extrusion processing parameters such as moistur

Building Death Literacy Through Last Aid: An Examination of Agency, Ambivalence and Gendered Informal Caregiving Within the Swedish Welfare State

In the last two decades, health promotion strategies have gained significant attention in end-of-life care contexts—engendering greater focus on community and informal care in policy and healthcare spheres in liberal welfare-states. The emergence of health-promoting palliative care (HPPC) in the Nordic context presents a unique challenge to the abiding social contract of care which emphasizes the

Trade Unions, the Social Democratic Party and Labor Market Conflicts in Malmö, 1890–1910

According to labor movement historian Axel Uhlén, two local conflicts in Malmö have created a huge interest all around Sweden (Uhlén, A. (1949) Facklig kamp i Malmö under sju decennier (Malmö: Framtiden), p. 259). The first labor dispute is the woodworker’s strike in 1890, called the Malmö revolt when thousands of people demonstrated in the streets and squares in the city center. Both local police

Courtroom Ethnography : Exploring contemporary approaches, fieldwork and challenges

This book provides a comprehensive and interdisciplinary examination of courtroom ethnography. This collection gathers international researchers from a multitude of disciplines to explore three central themes: doing courtroom ethnography, ethnographic studies of the courtroom, and contemporary and critical aspects of courtroom ethnography. It highlights the nuances, negotiations, and issues that e

A prospective cohort study identifying radiologic and tumor related factors of importance for breast conserving surgery after neoadjuvant chemotherapy

Introduction: Neoadjuvant chemotherapy (NAC) is an established treatment option for early breast cancer, potentially downstaging the tumor and increasing the eligibility for breast-conserving surgery (BCS). The primary aim of this study was to assess the rate of BCS after NAC, and the secondary aim was to identify predictors of application of BCS after NAC. Materials and methods: This was an obser

Robust fusion for skin lesion segmentation of dermoscopic images

Robust skin lesion segmentation of dermoscopic images is still very difficult. Recent methods often take the combinations of CNN and Transformer for feature abstraction and multi-scale features for further classification. Both types of combination in general rely on some forms of feature fusion. This paper considers these fusions from two novel points of view. For abstraction, Transformer is viewe

Identification of phenotypically, functionally, and anatomically distinct stromal niche populations in human bone marrow based on single-cell RNA sequencing

Hematopoiesis is regulated by the bone marrow (BM) stroma. However, cellular identities and functions of the different BM stromal elements in humans remain poorly defined. Based on single-cell RNA sequencing (scRNAseq), we systematically characterized the human non-hematopoietic BM stromal compartment and we investigated stromal cell regulation principles based on the RNA velocity analysis using s

Adhesive wear of TiAlN coatings during low speed turning of stainless steel 316L

The wear behavior of TiAlN coatings during turning of stainless steel 316L at low cutting speeds (60–120 m/min) was investigated using scanning electron microscopy. In this speed range, the coatings fail by fracture due to an adhesive wear mechanism. The fracture of the coating is described in detail, including the strong influence of Al-content and cutting speed on the rate of wear. Low Al-conten

Parallel motion vision pathways in the brain of a tropical bee

Spatial orientation is a prerequisite for most behaviors. In insects, the underlying neural computations take place in the central complex (CX), the brain’s navigational center. In this region different streams of sensory information converge to enable context-dependent navigational decisions. Accordingly, a variety of CX input neurons deliver information about different navigation-relevant cues.

Short-Term Complications and Outcomes in Pharmaco-Mechanical Thrombolysis First and Catheter-Directed Thrombolysis First in Patients with Acute Lower Limb Ischemia

Background: Pharmaco-mechanical thrombolysis (PMT) has emerged as a treatment option in patients with acute lower limb ischemia (ALI), especially Rutherford IIb (motor deficit) for rapid revascularization, but supportive data is scarce. The aim of the present study was to compare the effects of thrombolysis, complications, and outcomes of PMT first versus catheter-directed thrombolysis (CDT) first

Binge-reading on immune thrombocytopenia : Everything you ever wanted to know

Immune thrombocytopenia (ITP) is a complex clinical and pathophysiological autoimmune disorder and in the past decade, thousands of papers have been published on this topic. To shed light on the global scientific output, Ou et al. performed a comprehensive bibliometric analysis of the ITP literature to clarify the major hotspots and future research directions. Commentary on: Ou et al. A bibliometr

Active sensitization to dimethylthiocarbamylbenzothiazol sulphide : An unexpectedly strong rubber contact allergen

Background: The two dialkylthiocarbamyl benzothiazole sulphides, dimethyl-thiocarbamylbenzothiazole sulphide (DMTBS) and diethylthio-carbamylbenzothiazole sulphide (DETBS) were shown to be good markers of both thiuram and mercaptobenzothiazole sensitivity. Objectives: To investigate if DMTBS and/or DETBS could be better markers of contact allergy to common rubber additives than the ones currently

Investigating the Feasibility of using Scandinavian Agricultural Side Streams for the Development of Novel High-Moisture Meat Analogues

Meat analogues are products that are supposed to resemble meat in terms of texture, flavour, and also sensory characteristics. They have recently become increasingly popular due to numerous issues related to health, religion, environmental impact and the growing number of vegetarians and vegans. Due to this reason, many plant-based protein materials, including grains, legumes, microalgae, and mush