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Hur upplever sjuksköterskor förberedelser av barn inför vård och behandling? - Systematisk litteraturöversikt och metasyntes

Abstrakt. Bakgrund: Sjuksköterskor möter barn med varierande bakgrunder, hemsituationer och med funktionsnedsättningar. Sjuksköterskan bör därför ha kunskap om barnets utveckling samt hälsa och ohälsa. Barnkompetens behövs för att möta barnens behov, vilket ger barnet tillit och förtroende för vårdpersonalen. Syfte: Syftet med studien var att belysa hur sjuksköterskor upplever förberedelser a

Antihelium-3 fluxes near Earth using data-driven estimates for annihilation cross section

Antinuclei found in cosmic rays could provide a smoking gun signal for dark matter as this signal is virtually background free. The study of 3He cosmic rays requires the knowledge of their production, propagation in the galaxy and annihilation cross-section. While the former two have been already estimated with data-driven methods, there were no experimental data available for the 3He inelastic cr

Geophysical mapping of groundwater properties for transport infrastructure construction planning - Final report

Framgången och kostnaderna för infrastrukturprojekt beror till stor del på tillförlitlig karakterisering av undermarken. Speciellt är information om grundvattnet avgörande för att skydda grundvattenresurserna och för att undvika stabilitetsproblem. För att fastställa de hydrogeologiska egenskaperna genomförs borrningar följt av hydrauliska tester som är tillförlitliga men dyra, och det ger endast The success and costs of infrastructure projects largely depend on reliable characterization of the subsoil, where information on groundwater is essential to protect groundwater resources and to avoid stability problems. To determine the hydrogeological characteristics, drilling is carried out followed by hydraulic tests which are reliable but expensive and provide limited information which, in so

Monte Carlo Simulations and Validation of NectarCAM, a Medium Sized Telescope Camera for CTA

The upcoming Cherenkov Telescope Array (CTA) ground-based gamma-ray observatory will open up our view of the very high energy Universe, offering an improvement in sensitivity of 5-10 times that of previous experiments. NectarCAM is one of the proposed cameras for the Medium-Sized Telescopes (MST) which have been designed to cover the core energy range of CTA, from 100 GeV to 10 TeV. The final came

Pooled Analysis of Meningioma Risk Following Treatment for Childhood Cancer

Importance: Meningioma is the most common subsequent neoplasm following cranial irradiation among survivors of childhood cancer, but there are still uncertainties regarding the magnitude of the radiation dose-response association, potential modifiers of radiation risks, and the role of chemotherapy. Objective: To evaluate meningioma risk in survivors of childhood cancer following radiotherapy and

Six Major Steps to Make Investigations of Suicide Valuable for Learning and Prevention

Objective: The decline in suicide rates has leveled off in many countries during the last decade, suggesting that new interventions are needed in the work with suicide prevention. Learnings from investigations of suicide should contribute to the development of these new interventions. However, reviews of investigations have indicated that few new lessons have been learned. To be an effective tool,

Microarray profiling of hypothalamic gene expression changes in Huntington's disease mouse models

Structural changes and neuropathology in the hypothalamus have been suggested to contribute to the non-motor manifestations of Huntington's disease (HD), a neurodegenerative disorder caused by an expanded cytosine-adenine-guanine (CAG) repeat in the huntingtin (HTT) gene. In this study, we investigated whether hypothalamic HTT expression causes transcriptional changes. Hypothalamic RNA was isolate

Prototype Open Event Reconstruction Pipeline for the Cherenkov Telescope Array

The Cherenkov Telescope Array (CTA) is the next-generation gamma-ray observatory currently under construction. It will improve over the current generation of imaging atmospheric Cherenkov telescopes (IACTs) by a factor of five to ten in sensitivity and it will be able to observe the whole sky from a combination of two sites: a northern site in La Palma, Spain, and a southern one in Paranal, Chile.

Cohort profile : Bladder Cancer Data Base Sweden (BladderBaSe) 2.0

PURPOSE: We constructed Bladder Cancer Data Base Sweden (BladderBaSe) 2.0 to expand studies in BladderBaSe on incidence, treatment outcomes, side effects, survival and health economic aspects of men and women with cancer in the urinary bladder, upper tract urothelial carcinoma (UTUC) (renal pelvis and ureter) and urethral carcinoma. PARTICIPANTS: BladderBaSe 2.0 includes 53 298 patients with cance

Latest developments in sustainability reporting: How the TCFD framework shapes the understanding of climate risks

This thesis explores how the latest trends in sustainability reporting are shaping the understanding of climate-related risks. Having the Task Force on Climate-Related Financial Disclosures (TCFD) framework as a proxy, this thesis focuses on the double materiality perspective, namely on how new disclosures are related not only to organizational efforts in lowering emissions, but on disclosures bas

Clinical impact of influenza vaccination after ST- and non-ST-segment elevation myocardial infarction - insights from the IAMI trial

Background: Influenza vaccination early after myocardial infarction (MI) improves prognosis but vaccine effectiveness may differ dependent on type of MI. Methods: A total of 2,571 participants were prospectively enrolled in the Influenza vaccination after myocardial infarction (IAMI) trial and randomly assigned to receive in-hospital inactivated influenza vaccine or saline placebo. The trial was c

Den statliga lönegarantin - Förbättringsåtgärder för ett minskat missbruk av lönegarantisystemet

Den statliga lönegarantin är en skyddslagstiftning som ger arbetstagare rätt till ersättning om arbetsgivaren går i konkurs. I en granskande rapport från Riksrevisionen framkommer det att 6–9 % av utbetalt garantibelopp utgörs av misstänkt missbruk av lönegarantin. Uppsatsens syfte är att undersöka om de föreslagna åtgärderna i Riksrevisionens granskning kan förväntas minska missbruk av lönegarantThe earnings guarantee is a legislation designated to compensate employees for loss of salary if the employer is declared bankrupt. In an audit by the Swedish National Audit Organization (the Swedish NAO), it is estimated that 6–9 % of all earnings guarantee payments consist of misusage. The purpose of this article is to examine if the measures suggested by the Swedish NAO can be considered adequa

CenTauRz : A standardized quantification of tau PET scans

Background: Over the past decade, several PET tracers were developed to visualise and quantify tau pathology in vivo. However, all these tracers have distinct off-target binding, different dynamic ranges and likely different levels of non-specific binding resulting in large variability in semiquantification. We propose to standardise the sampling and the quantification across all available tau tra

Computational Evidence Based Perspective on the Plausible Repositioning of Fluoroquinolones for COVID-19 Treatment

The coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become a serious global healthcare crisis, so there is an emergence of identifying efficacious therapeutic options. In a setting where there is an unavailability of definitive medication along with the constant eruption of vaccine-related controversies, the drug-repositioning appr

En kvalitativ studie om tjejers uppbrottsprocesser från en våldsam relation

The following study consists of a qualitative analysis based on six heterosexual girls' stories about the way out of their violent relationship. The purpose of the study was to gain an increased understanding of the six girls' leaving processes and which factors led to the final breakup. The empirical material was based on six podcast episodes where the girls talked about their experience

Integrative pathway enrichment analysis of multivariate omics data

Multi-omics datasets represent distinct aspects of the central dogma of molecular biology. Such high-dimensional molecular profiles pose challenges to data interpretation and hypothesis generation. ActivePathways is an integrative method that discovers significantly enriched pathways across multiple datasets using statistical data fusion, rationalizes contributing evidence and highlights associate

“I would love to be ‘discredited’ like this more often” : An interview with Irving Kirsch

This interview with Professor Irving Kirsch took place in late August, 2022. He recently turned 80 years old and agreed to focus his interview on topics and areas that illustrate his influence on the field of hypnosis. Professor Kirsch discusses the influences that shaped him as a person and scientist; what unites his theoretical and research work on hypnosis, placebo, and antidepressants. He also

Upper bounds on focusing efficiency

Upper bounds on the focusing efficiency of aperture fields and lens systems are formulated using integral equation representations of Maxwell’s equations and Lagrangian duality. Two forms of focusing efficiency are considered based on lens exit plane fields and optimal polarization currents within lens design regions of prescribed shape and available materials. Bounds are compared against the perf