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Energin under mark ska upp till ytan : Strategisk innovationsagenda för geoenergi

The Swedish Strategic Innovation Agenda for Geoenergy develops a strategy for highlighting the need for geoenergy research, development and innovation in relation to the business community and authorities. Sweden has a strong global position in the field. Geothermal energy is the third­largest renewable energy source in Sweden, along with wind power. Currently, approximately 18 TWh of renewable he

Floating Thermal Piles in Soft Sensitive Clays

Thermal piles are building foundation piles which, in addition to transferring the load of the building to the ground, are also used as heat exchangers to provide thermal exchange with the ground. This article shortly presents field testing of thermal piles installed in soft sensitive clay in Gothenburg. The aim of the field tests is to study the thermo-mechanical response of the heating and cooli

A comparative cost analysis of conventional wrought steel and powder metallurgy (PM) gear manufacturing technologies

The transportation industry landscape is going through a massive transformation due to trends such as autonomous and electrified vehicles. The electrification trend has already started to display its ample influence on the automotive industry. New modern power and drivetrains need to be designed and manufactured based on the raising automakers’ requirements e.g. higher performance, better noise vi

Reduced Expression of PLCXD3 Associates With Disruption of Glucose Sensing and Insulin Signaling in Pancreatic β-Cells

Previous work has shown that reduced expression of PLCXD3, a member of the phosphoinositide-specific phospholipases (PI-PLC) family, impaired insulin secretion with an unclear mechanism. In the current study, we aim to investigate the mechanism underlying this effect using human islets and rat INS-1 (832/13) cells. Microarray and RNA sequencing data showed that PLCXD3 is among the highly expressed

Hemogenic Reprogramming of Human Fibroblasts by Enforced Expression of Transcription Factors

The cellular and molecular mechanisms underlying specification of human hematopoietic stem cells (HSCs) remain elusive. Strategies to recapitulate human HSC emergence in vitro are required to overcome limitations in studying this complex developmental process. Here, we describe a protocol to generate hematopoietic stem and progenitor-like cells from human dermal fibroblasts employing a direct cell

Effect of excess charge carriers and fluid medium on the magnitude and sign of the Casimir-Lifshitz torque

Last year, we reported a perturbative theory of the Casimir-Lifshitz torque between planar biaxially anisotropic materials in the retarded limit [Thiyam et al., Phys. Rev. Lett. 120, 131601 (201810.1103/PhysRevLett.120.131601)], which is applied here to study the change in sign and magnitude of the torque with separation distance in biaxial black phosphorus having excess charge carriers. The study

A nutrient-wide association study for risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition and the Netherlands Cohort Study

Purpose: The evidence from the literature regarding the association of dietary factors and risk of prostate cancer is inconclusive. Methods: A nutrient-wide association study was conducted to systematically and comprehensively evaluate the associations between 92 foods or nutrients and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC). Cox proportio

Bullying and Pain in School-Aged Children and Adolescents : A Cross-Sectional Study

Bullying is defined as repeated and unwanted aggressive behavior involving a power imbalance and hurt children and adolescents’ socioemotional functioning. The aim is to investigate associations between pain (headache, stomach pain, backache, and neck/shoulder pain) and bullying among school-aged children and adolescents. This cross-sectional school-based survey comes from the Icelandic data set i

A Case Study on the Influence of Multiple Users on the Effective Channel in a Massive MIMO System

We investigate the importance of weak clusters when modeling a wireless massive MIMO channel. We do this by studying the influence of densely spaced terminals and the number of base-station antennas for a zero-forcing precoded massive MIMO system. In particular, we focus on the influence on the correlation and imbalance between the signals at the terminal antennas, the effective channel-gain, the

Improving risk prediction in heart failure using machine learning

Background: Predicting mortality is important in patients with heart failure (HF). However, current strategies for predicting risk are only modestly successful, likely because they are derived from statistical analysis methods that fail to capture prognostic information in large data sets containing multi-dimensional interactions. Methods and results: We used a machine learning algorithm to captur

The impact of endurance training and table soccer on brain metabolites in schizophrenia

Higher glutamate and glutamine (together: Glx) and lower N-acetyl-aspartate (NAA) levels were reported in schizophrenia. Endurance training normalizes NAA in the hippocampus, but its effects on other metabolites in the brain and the relationship of metabolites to clinical symptoms remain unknown. For 12 weeks, 20 schizophrenia inpatients (14 men, 6 women) and 23 healthy controls (16 men, 7 women)

Diagnosis and long-term outcome in dogs with acute onset intracranial signs

Objectives: To investigate dogs with acute onset of intracranial signs suspected of stroke by primary veterinary clinicians, and establish possible differential diagnoses and long-term outcome. In addition, serum C-reactive protein and plasma cytokines were investigated as potential biomarkers of disease. Materials and Methods: All cases were evaluated by neurologic examination, routine haematolog

Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype

SUGCT (C7orf10) is a mitochondrial enzyme that synthesizes glutaryl-CoA from glutarate in tryptophan and lysine catabolism, but it has not been studied in vivo. Although mutations in Sugct lead to Glutaric Aciduria Type 3 disease in humans, patients remain largely asymptomatic despite high levels of glutarate in the urine. To study the disease mechanism, we generated SugctKO mice and uncovered imb

The chemokine CXCL16 is a new biomarker for lymph node analysis of colon cancer outcome

Chemokines are important in the development and progression of tumors. We investigated the expression of CXCL14 and CXCL16 in colon cancer. Expression of mRNA was assessed in primary tumors and lymph nodes and CXCL16 mRNA levels were correlated to patient’s survival. Protein expression was investigated by two-color immunofluorescence and immunomorphometry. CXCL14 and CXCL16 mRNA levels and protein

Risk-Adapted Starting Age of Screening for Relatives of Patients with Breast Cancer

Importance: Breast cancer screening guidelines acknowledge the need for earlier screening for women at increased risk but provide limited guidance for women with a family history of breast cancer. A risk-adapted starting age of screening for relatives of patients with breast cancer may help supplement current screening guidelines. Objective: To identify the risk-adapted starting age of breast canc

A Convivial Journey : From Diversity in Istanbul to Solidarity with Refugees in Denmark

This chapter presents my analytical journey from conviviality, a concept used for analysing diversity in Istanbul to overcome the pitfalls of multiculturalism and coexistence theories, to the development of the concept of convivial solidarity for the analysis of transnational civil society organisations that support refugees and migrants in Denmark. Convivial solidarity is my construct and I use i