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OBJECTIVE: Charcot foot (CF) requires prolonged offloading of the affected foot to decrease the risk of deformity. The earliest phase in active CF (stage 0) is characterized by inflammatory signs without established fractures or skeletal deformity. We investigated whether offloading in stage 0 influences duration of total contact casting (TCC), risk of recurrence, and future need for surgery.RESEA

Background: Tumour deposits are suggested to impact prognosis in colon cancer negatively. This study assessed the impact of tumour deposits on oncological outcomes.Methods: Data from the Swedish Colorectal Cancer Registry for patients who underwent R0 abdominal surgery for TNM stage I-III colon cancer between 2011 and 2014 with 5-year follow-up were analysed with multivariable analysis. Patients w

This article analyzes the appropriate types of water rights systems for different regions with varying water resource conditions in China. The most appropriate water rights systems for various zones were determined by comparing the value of influencing factors with corresponding thresholds in China’s second-class zones of water resources. It is shown that a riparian rights system under water withd

How different were the lives of elites and commoners in early complex societies? This paper examines this question using data from three fisher-hunter-gatherer sites in southern California. Using shell bead counts from burials as proxies for social status and previously published human stable isotope values as indicators of dietary practices, we examine the relationship between diet and status acr

Inteins are self-splicing protein elements found in viruses and all three domains of life. How the DNA encoding these selfish elements spreads within and between genomes is poorly understood, particularly in eukaryotes where inteins are scarce. Here, we show that the nuclear genomes of three strains of Anaeramoeba encode between 45 and 103 inteins, in stark contrast to four found in the most inte

INTRODUCTION: Many depressed patients do not achieve remission with available treatments. Anhedonia is a common residual symptom associated with treatment resistance as well as low function and quality of life. There are currently no specific and effective treatments for anhedonia. Some trials have shown that dopamine agonist pramipexole is efficacious for treating depression, but more data is nee

The study objective in this article was to present the state-of-the-art on teachers’ professional development to enhance educational quality for students with autism spectrum disorders (ASD) in primary and secondary education. A systematic review was conducted, following the PRISMA guidelines. Quantitative, qualitative, and mixed-methods studies were eligible for inclusion. Fifteen studies were id

This study examined whether teachers’ professional development of their relational competence with students with attention deficit hyperactivity disorder (ADHD) and/or autism spectrum disorder (ASD) modifies teachers’ and students’ perceptions of their teacher-student relationships (TSR). Participants comprised teachers (n = 33) and students (n = 232) from two elementary schools: one intervention

Kraven på försvagad konflikt­rätt hotar Sveriges välfungerande lönebildning och riskerar att öka arbetslivs­kriminaliteten. I förlängningen väntar ingrepp från politiker och från EU.

Bayesian phylogenetics is now facing a critical point. Over the last 20 years, Bayesian methods have reshaped phylogenetic inference and gained widespread popularity due to their high accuracy, the ability to quantify the uncer‑ tainty of inferences and the possibility of accommodating multiple aspects of evolutionary processes in the models that are used. Unfortunately, Bayesian methods are compu

Exhaled SARS-CoV-2-containing aerosols contributed significantly to the rapid and vast spread of covid-19. However, quantitative experimental data on the infectivity of such aerosols is missing. Here, we quantified emission rates of infectious viruses in exhaled aerosol from individuals within their first days after symptom onset from covid-19. Six aerosol samples from three individuals were cultu

Sedan 1920-talet har det funnits planer på att använda contortatall i svenskt skogsbruk men först kring 1970omsattes de till storskaliga planteringar i norra Sverige.Sedan 1970-talet har contortatallen debatterats och knutits till olika sammanhang och skilda värderingsregimer.Återkommande har forskare samt företrädare för skogsnäringen och olika miljörörelser försökt att avgränsacontortans betydel

In this paper, Safety Control Barrier Functions (SCBFs) were used to adjust the null-space compliant behavior of a redundant robot to improve safety in Human–Robot Collaboration (HRC) without modifying the robot behavior with respect to its main Cartesian task. A Lyapunov function was included in an energy storage formulation compatible with strict passivity to provide global asymptotic stability

Geobotanical subdivision of landcover is a baseline for many studies. The High–Low Arctic boundary is considered to be of fundamental natural importance. The wide application of different delimitation schemes in various ecological studies and climatic scenarios raises the following questions: (i) What are the common criteria to define the High and Low Arctic? (ii) Could human impact significantly

Across many species, a major function of vocal communication is to convey formidability, with low voice frequencies traditionally considered the main vehicle for projecting large size and aggression. Vocal loudness is often ignored, yet it might explain some puzzling exceptions to this frequency code. Here we demonstrate, through acoustic analyses of over 3,000 human vocalizations and four percept

When an atom is driven by a laser field with a photon energy that is nearly resonant with an atomic transition, it can undergo periodic population transfers between the ground and excited state, known as Rabi oscillations [1,2]. The aim of this work is to study photoionization from atoms for parameters accessible to a free-electron laser (FEL) [3]. Using time dependent perturbation theory to model

The new imaging endstation of the NanoMAX beamline is being designed to complement the already existing diffraction endstation: measurements with smaller beams at lower photons energies, with higher stability, in vacuum and with sample cooling at the measurement position, optimized for X-ray fluorescence mapping and ptychographic imaging in two and three spatial dimensions. This comes at the cost

Herein, we present the synthesis of two new dicobaloxime complexes, [{ClCo(dmgH)2(4-PyCOO)}2Zn(DMF)2] (1) and [{ClCo(dmgH)2(4-PyCOO)}2Cd(H2O)3(DMF)].4H2O (2) bridged by isonicotinate-Zn(ii) and Cd(ii) moieties. These complexes were synthesized upon reaction of a monomeric chlorocobaloxime [ClCo(dmgH)2(4-PyCOOH)] with Zn(NO3)2·6H2O and Cd(OAc)2·2H2O in a methanol/DMF solvent mixture. Both complexes