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A practical approach for supporting decisions in bridge condition assessment and monitoring

In this contribution a practical and rational decision-making approach is presented to be applied for common bridges typically managed by public authorities. The authors have developed a model with the intention to be applicable for practical cases for common bridges in the daily work of bride operators responsible for a large number of assets, yet still maintain the principles of more generic fra

MORPHOLOGICAL MODELING OF TIDAL INLET EVOLUTION: AN APPLICATION TO MUNDAÚ INLET, BRAZIL

The aim of this study was to develop a morphological model for long-term inlet evolution to be applied using a minimum amount of input data and requiring low computational costs. The model was implemented numerically and then validated for a real inlet application: Mundaú inlet (northeastern Brazil), a dynamic inlet with a marked freshwater seasonality and alongshore sand transport, reduced by ree

A SEMI-ANALYTIC MODEL OF TIDAL INLETS AND THEIR EVOLUTION

The water exchange between the sea and a lagoon or bay through an inlet due to tides is a classical topic that has been investigated in a large number of studies (Keulegan, 1967; O’Brien and Dean, 1972; O’Brien and Clark, 1974; Escoffier, 1977). In this paper, a simple semi-analytic model of the flow induced by tides through an inlet connecting the sea to a lagoon or bay is developed. The model is

Scoliosis in cerebral palsy

Cerebral pares (CP) är den vanligaste orsaken till motorisk funktionsnedsättning hos barn och ungdomar och årligen föds ca 200 barn med CP i Sverige. Symtomen vid CP varierar, men karaktäriseras av bland annat nedsatt rörelseförmåga och nedsatt förmåga att stabilisera kroppen. Nästan åtta av tio vuxna med CP besväras av korta och spända muskler, snedställda leder och smärta som påverkar deras funkBackgroundIndividuals with cerebral palsy (CP) have an increased risk for scoliosis, especially those with low gross motor function, affecting both quality of life and overall function. The aims were to increase the knowledge on the development of, and predictors for scoliosis and the use of spinal orthoses in individuals with CP, and also to evaluate the Caregiver Priorities and Child Health Inde

Feature analysis and prediction of ice regime in the source region of the Yellow River

The Yellow River is a river where serious ice disasters frequently take place in winter. In recent years, the stable frozen period has decreased and the frequency of intermittent freeze periods has increased. After analysing the main factors influencing the ice regime, the prediction factors can be selected. Using multiple linear regression (MLR) and artificial neural network (ANN) methods, this p

A Single-Electron Transistor Made of a 3D Topological Insulator Nanoplate

Quantum confined devices of 3D topological insulators are proposed to be promising and of great importance for studies of confined topological states and for applications in low-energy-dissipative spintronics and quantum information processing. The absence of energy gap on the topological insulator surface limits the experimental realization of a quantum confined system in 3D topological insulator

Second Primary Cancers in Patients with Invasive and In Situ Squamous Cell Skin Carcinoma, Kaposi Sarcoma, and Merkel Cell Carcinoma : Role for Immune Mechanisms?

Second primary cancers (SPCs) are becoming a common cancer entity, which may interfere with survival in relatively benign first primary cancers. We examined the hypothesis that immune dysfunction may contribute to SPCs by assessing SPCs associated with known immune responsive skin cancers, invasive and in situ squamous cell carcinoma, Kaposi sarcoma, and Merkel cell carcinoma. Cancers were identif

A minimal model for the latitudinal diversity gradient suggests a dominant role for ecological limits

The latitudinal diversity gradient (LDG) is one of Earth’s most iconic biodiversity patterns and still one of the most debated. Explanations for the LDG are often categorized into three broad pathways in which the diversity gradient is created by (1) differential diversification rates, (2) differential carrying capacities (ecological limits), or (3) differential time to accumulate species across l

Impact of Baseline Anemia in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention : A Prespecified Analysis From the VALIDATE-SWEDEHEART Trial

Background The impact of baseline anemia in a contemporary acute coronary syndrome (ACS) population undergoing percutaneous coronary intervention in the era of predominant radial artery access, potent P2Y12 inhibition, and rare use of glycoprotein IIb/IIIa inhibitors has not been adequately studied. Methods and Results ACS patients who underwent percutaneous coronary intervention between 2014 and

A novel starch-binding laccase from the wheat pathogen Zymoseptoria tritici highlights the functional diversity of ascomycete laccases

Background: Laccases are multicopper oxidases, which are assigned into auxiliary activity family 1 (AA1) in the CAZy database. These enzymes, catalyzing the oxidation of phenolic and nonphenolic substrates coupled to reduction of O2 to H2O, are increasingly attractive as eco-friendly oxidation biocatalysts. Basidiomycota laccases are well characterized due to their potential in de-lignification of

Effects of insulin and the glucagon-like peptide 1 receptor agonist liraglutide on the kidney proteome in db/db mice.

Diabetes mellitus (DM) is a worldwide disease that affects 9% of the adult world population and type 2 DM accounts for 90% of those. A common consequence of DM is kidney complications, which could lead to kidney failure. We studied the potential effects of treatment with insulin and the glucagon-like peptide 1 receptor (GLP-1R) agonist liraglutide on the diabetic kidney proteome through the use of

Compendium of Front-End Electronics

Our world is changing fast. On one hand, technological developments provide us with new and powerful electronics devices on almost a weekly basis. On the other hand, the end-user of these electronics is now rarely required to actually configure the devices, as everything is automated. This "de-empowerment" of the end-user may be detrimental to the scientific community. This is because the unique c

Sentinel Lymph Node Biopsy in Thyroid Cancer

Background: Prophylactic central neck dissection in patients with papillary thyroid carcinoma is controversial. Sentinel node biopsy might be an adjunct to optimize surgical treatment for these patients. Earlier studies reported inconsistent detection rates and diagnostic value of this technique, and the role of sentinel lymph node biopsy in thyroid cancer needs to be established. Patients and met

The Dislocated Vernacular in Translated Swedish Working-Class Fiction

When a literary text is translated from a dominated to a dominating language, Yvonne Lindqvist (2018) observes, it generally undergoes a cosmopolitanizing process. Consecrated by the dominating literary culture, the text is lifted up to a transnational level and deemed significant for an international readership. Lindqvist’s observation is confirmed by the English translations of Swedish working-c