Purpose: None of the key randomised trials on the omission of axillary lymph node dissection (ALND) in sentinel lymph-positive breast cancer have reported external validity, even though results indicate selection bias. Our aim was to assess the external validity of the ongoing randomised SENOMAC trial by comparing characteristics of Swedish SENOMAC trial participants with non-included eligible pat

The changing landscape of treatment options for multiple myeloma has led to a higher proportion of patients achieving deep, long-lasting responses to therapy. With the associated improvement in overall survival, the development of subsequent second malignancies has become of increased significance. The risk of second malignancy after multiple myeloma is affected by a combination of patient-, disea

This study numerically investigates film-cooling performance and particle trajectories in AGTB (two rows of cylindrical holes equipped on suction side (SS) and pressure side (PS) of the leading edge, respectively) turbine cascade. Particle deposition on a turbine blade is analyzed by calculations of capture efficiency and impact efficiency. The turbulent flow is modeled by the Realizable k-ε turbu

This paper explores public attitudes towards science and nature in twelve countries using data from the International Social Survey Programme environment modules of 1993, 2000, and 2010. Analysis of attitude items indicates technocentric and pessimistic dimensions broadly related to the Dominant Social Paradigm and New Environmental Paradigm. A bi-axial dimension scale is utilized to classify resp

Purpose: To evaluate the feasibility of oral cryotherapy (OC) in children and to investigate if OC reduces the incidence of severe oral mucositis (OM), oral pain, and opioid use in children undergoing hematopoietic stem cell transplantation (HSCT). Methods: Fifty-three children, 4–17 years old, scheduled for HSCT in Sweden were included and randomized to OC or control using a computer-generated li

ABSTRACTThis article investigates Twitter data related to the kidnapping case of two German nationals in the southern region of the Philippines by the Abu Sayyaf Group (ASG). It explores perceptions of the ASG, along with associated organizations and sentiments indicated in the tweets together with statistically significant relationships. Findings revealed that: ?Rebel? and ?Militant? were the mos

Data from the International Social Survey Programme 2000 and 2010 environment modules were analyzed to explore the relationships between attitudes, behavior, and sociodemographic variables to citizens’ preferences to aspects of environmental discourse in the Philippines. Overall, significantly more people agree to multilateralism, equity, and the link between the environment and economic progress

BACKGROUND: Amyloid-β positron emission tomography (PET) and cerebrospinal fluid (CSF) Aβ42 are considered interchangeable for clinical diagnosis of Alzheimer's disease. OBJECTIVE: To explore the clinical reasoning for requesting additional amyloid-β PET after performing CSF biomarkers. METHODS: We retrospectively identified 72 memory clinic patients who underwent amyloid-β PET after CSF biomarker

The PODMT3DMS-Tool, which consists of a proper orthogonal decomposition (POD) linked to the Modular Transport 3-Dimensional Multi Species (MT3DMS) code for nitrate simulation in groundwater, is introduced. POD, as a statistical technique, reduces a large amount of information produced by the MT3DMS model to provide the main components of the PODMT3DMS-Tool, i.e., space- and time-dependent terms of

The field synergy principle has three criteria to qualitatively describe the essence of single-phase convective heat transfer enhancement. However, in practice these criteria are difficult to be applied to convective heat transfer analysis, because there are no corresponding indicators available to quantitatively describe them. Therefore, a unified formula for the field synergy principle was devel

Lupus nephritis is a chronic autoimmune-inflammatory condition that can lead to end-stage kidney disease. Presently available immunosuppressive treatments for lupus nephritis are suboptimal and can induce significant side effects. Recently, we characterized a novel immunomodulatory activity of the minor isoform of the classical pathway complement inhibitor, C4BP(β-). We show here that C4BP(β-) tre

A new genus, Lasalleistichus, is described based on material from the Neotropical region (Brazil, Costa Rica, Peru). This new genus includes four species: L. albiclava, L. albifasciatus, L. fuscicoxa, L. longicaulis, all spp. n. and described here. The group is mainly female based, males are known only for L. albiclava. There is no biological information available for this group. http://www.zooban

Multiple scattering of electromagnetic waves by a discrete collection of scatterers is a well-studied subject, and many excellent treatments are found in the literature. The deterministic analysis of the scattering problem in this chapter is an extension of the problems treated previosly. Moreover, the present analysis generalizes the established results in two previous papers to a geometry with a

Prostate cancer (PCa) is an interesting study case of clinical management of uncertainty. PCa is the most diagnosed but only the second-leading cause of non-cutaneous cancer-related mortalities among men in developed countries. To put simply, the life-time risk of PCa diagnosis and mortality is approximately 11% and 3% respectively; a ~3.6-fold difference. The large number of PCa incidence is attr

Agriculture faces enormous challenges including the need to substantially increase productivity, reduce environmental footprint, and deliver renewable alternatives that are being addressed by developing new oil crops for the future. The efforts include domestication of Lepidium spp. using genomics-aided breeding as a cold hardy perennial high-yielding oil crop that provides substantial environment

Version 3 av ecoinvent är den första databasen att erbjuda möjligheten att koppla samman livscykelinventeringar (LCI) utefter olika länkningsalgoritmer. Genom dessa länkningsalgoritmer tar ecoinvent nu fram bakgrundslivscykelinventeringar med både medeldata och långsiktig marginaldata (t.ex. över elmarknader i olika länder). Idealt sett representerar långsiktig marginaldata över elmarknader den ytVersion 3 of the ecoinvent database is the first background database to offer the possibility to link life cycle inventories (LCI) according to different linking algorithms. Using those algorithms, ecoinvent now provides both average and long-term, marginal background LCI data, (e.g. for electricity markets for different countries). Long-term, marginal data for electricity markets ideally represen