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Recurrent acute otitis media - aetiology, diagnostics and prevention

Popular Abstract in Swedish Akut mediaotit - öroninflammation - är den vanligaste bakteriella infektionen hos barn. Den vanligaste öroninflammationsbakterien är pneumokocken. Öroninflammation är en infektion som varierar stort i svårighetsgrad; medan många öroninflammationer läker utan behandling kan andra ge upphov till livshotande komplikationer. Eftersom självläkningsfrekvensen är ganska hög oAcute otitis media (AOM) is the most common bacterial infection in children. The clinical course varies from spontaneous recovery to life-threatening complications, and this variability mainly depends on the causative pathogen. Bacteria usually invade the middle ear from the nasopharynx, where they are carried frequently, both during sickness and health. The most common bacterium to cause AOM, and

Modelling uncertainty for nitrate leaching and nitrous oxide emissions based on a Swedish field experiment with organic crop rotation

High uncertainties are common in detailed quantification of the N budget of agricultural cropping systems. The process-based CoupModel, integrated with the parameter calibration method known as Generalized likelihood uncertainty estimation (GLUE), was used here to define parameter values and estimate an N budget based on experimental data from an organic farming experiment in south-west Sweden. Da

Body mass changes in a biparental incubator: the Redshank Tringa totanus

Incubation is a period of high energetic costs and accordingly body mass losses are often detected. Why birds lose body mass during incubation is not well understood; suggestions are that it is either a consequence of energetic constraints or adaptations to an optimal mass trajectory. We studied body mass changes through the incubation period in the Common Redshank Tringa totanus, a biparental inc

Transfer of vibrational coherence through incoherent energy transfer process in Forster limit

We study transfer of coherent nuclear oscillations between an excitation energy donor and an acceptor in a simple dimeric electronic system coupled to an unstructured thermodynamic bath and some pronounced vibrational intramolecular mode. Our focus is on the nonlinear optical response of such a system, i.e., we study both excited state energy transfer and the compensation of the so-called ground-s

Effective pseudopotential for energy density functionals with higher-order derivatives

We derive a zero-range pseudopotential that includes all possible terms up to sixth order in derivatives. Within the Hartree-Fock approximation, it gives the average energy that corresponds to a quasilocal nuclear energy density functional (EDF) built of derivatives of the one-body density matrix up to sixth order. The direct reference of the EDF to the pseudopotential acts as a constraint that di

Detailed diesel exhaust characteristics including particle surface area and lung deposited dose for better understanding of health effects in human chamber exposure studies.

Several diesel exhaust (DE) characteristics, comprising both particle and gas phase, recognized as important when linking with health effects, are not reported in human chamber exposure studies. In order to understand effects of DE on humans there is a need for better characterization of DE when performing exposure studies. The aim of this study was to determine and quantify detailed DE characteri

Symptoms and aspects on eosinophil activity in allergic rhinitis

Allergic rhinitis is a major atopic disease. Even if much is known about the pathophysiology of this condition, and despite the fact that good treatments are available, there is a need for new treatment options, particularly for such aiming at new targets and reduced side effects. Recruitment and activation of eosinophils is a key feature of allergic rhinitis. Eosinophils have different activatio

A novel nonlinear model reduction method applied to automotive controller software

The automotive industry is experiencing tightening emission legislations together with high demands on performance and driveability. As a counteraction, controller software tends to become more and more complex. Intricate controller software has several downsides, the large number of controller parameters yields an exhaustive calibration task, often performed through costly experiments. In additio

A 5GHz 90-nm CMOS all digital phase-locked loop

An all digital phase-locked loop (ADPLL) has been implemented in a 90-nm CMOS process. It uses a phase-frequency detector (PFD) connected to two time-to-digital converters (TDC). To save power the TDCs use delay line cells with uneven delay time. During frequency acquisition an automatic tuning bank controller selects active bank of the digitally controlled oscillator (DCO), which features three s

Inherited genetic susceptibility to multiple myeloma

Although the familial clustering of multiple myeloma (MM) supports the role of inherited susceptibility, only recently has direct evidence for genetic predisposition been demonstrated. A meta-analysis of two genome-wide association (GWA) studies has identified single-nucleotide polymorphisms (SNPs) localising to a number of genomic regions that are robustly associated with MM risk. In this review,

Electronic properties of grain boundaries in Cu(In,Ga)Se-2 thin films with various Ga-contents

We present a study on the electronic properties of grain boundaries (GBs) in polycrystalline Cu(In,Ga)Se-2 (CIGSe) thin films by means of Kelvin probe force microscopy. As grown as well as KCN-treated films were investigated comparatively. No influence of the chemical treatment on the electronic properties of GBs was found. GBs generally exhibited large variations in their electronic properties. B

Palaeoclimate inferred from δO and palaeobotanical indicators in freshwater tufa of Lake Äntu Sinijärv, Estonia

We investigated a 3.75-m-long lacustrine sediment record from Lake Äntu Sinijärv, northern Estonia, which has a modeled basal age >12,800 cal yr BP. Our multi-proxy approach focused on the stable oxygen isotope composition (δ18O) of freshwater tufa. Our new palaeoclimate information for the Eastern Baltic region, based on high-resolution δ18O data (219 samples), is supported by pollen and plant ma

Housing and Health: Very Old People with Self-Reported Parkinson's Disease versus Controls.

Objectives. To explore whether aspects of housing and health among very old people with self-reported Parkinson's disease (PD) differ from matched controls. Methods. Data from the ENABLE-AGE Survey Study were used to identify people with self-reported PD (n = 20) and three matched controls/individual (n = 60). The matching criteria were age (mean = 82 years), sex, country, and type of housing. The

Variability of important vital rates challenges the demographic buffering hypothesis

Selection is assumed to eliminate life-histories showing high variability in vital rates that have the greatest influence on population performance. Therefore, an inverse variability-importance relationship of vital rates is believed to be a universal pattern for diverse life-histories. We tested for such a relationship using multi-year demographic data on a large number of populations of two pere

Role of dietary beta-glucans in the prevention of the metabolic syndrome.

The present review examines the evidence regarding the effect of β-glucan on variables linked to the metabolic syndrome (MetS), including appetite control, glucose control, hypertension, and gut microbiota composition. Appetite control can indirectly influence MetS by inducing a decreased energy intake, and promising results for a β-glucan intake to decrease appetite have been found using gut horm

Characterization and genome sequencing of two Propionibacterium acnes phages displaying pseudolysogeny

Background: Propionibacterium acnes is a Gram positive rod inhabiting the human skin that also infects orthopaedic implants and is associated with acne vulgaris. Previously, one lytic bacteriophage, PA6, from P. acnes has been sequenced and partially characterized. We recently isolated several inducible phages from P. acnes classified as Siphoviruses based on morphology and partial genome sequenci