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Background: Acute coronary syndromes most commonly arise from thrombosis of lipid-rich coronary atheromas that have large plaque burden despite angiographically appearing mild. Objectives: This study sought to examine the outcomes of percutaneous coronary intervention (PCI) of non–flow-limiting vulnerable plaques. Methods: Three-vessel imaging was performed with a combination intravascular ultraso
BACKGROUND: The comparative efficacy and safety of ticagrelor versus clopidogrel in older patients with myocardial infarction (MI) has received limited study. METHODS: We performed an observational analysis of all patients ≥80 years (n=14 005) who were discharged alive with aspirin combined with either clopidogrel (60.2%) or ticagrelor (39.8%) after a MI between 2010 and 2017 registered in the nat
We propose the Positive Resampler to solve the problem associated with event samples from state-of-the-art predictions for scattering processes at hadron colliders typically involving a sizeable number of events contributing with negative weight. The proposed method guarantees positive weights for all physical distributions, and a correct description of all observables. A desirable side product of
Cluster superlattice membranes consist of a two-dimensional hexagonal lattice of similar-sized nanoclusters sandwiched between single-crystal graphene and an amorphous carbon matrix. The fabrication process involves three main steps, the templated self-organization of a metal cluster superlattice on epitaxial graphene on Ir(111), conformal embedding in an amorphous carbon matrix, and subsequent li
This review presents a glossary and review of terminology used to describe the chemical and physical processes involved in soot formation and evolution and is intended to aid in communication within the field and across disciplines. There are large gaps in our understanding of soot formation and evolution and inconsistencies in the language used to describe the associated mechanisms. These inconsi
Regional species diversity is explained ultimately by speciation, extinction and dispersal. Here, we estimate dispersal and speciation rates of Neotropicaal butterflies to propose an explanation for the distribution and diversity of extant species. We focused on the tribe Brassolini (owl butterflies and allies), a Neotropical group that comprises 17 genera and 108 species, most of them endemic to
Laminated composites have so far received little attention as a potential material for gear drive applications. In the presented study, the thermomechanical performance of a newly developed type of epoxy impregnated, autoclave-cured carbon fibre-reinforced polymer gear—running in pair with a steel pinion—was analysed, using a combination of experimental and numerical approaches. The employed metho
Editor's notes: Non-Nyquist sampling-based event-triggered systems can enable adaptive sampling of IoT nodes resulting in large energy savings. This article reviews introductory concepts and building blocks of non-Nyquist sampling for cardiovascular monitoring systems. It further analyzes the performance of a knowledge-based adaptive sampling strategy applied to biophysiological signals such as el
Today, many control applications in cyber-physical systems are implemented on shared platforms. Such resource sharing may lead to complex timing behaviors and, in turn, instability of control applications. This paper highlights a number of anomalies demonstrating complex timing behaviors caused as a result of resource sharing. Such anomalous scenarios, then, lead to a dramatic increase in design c
Increasing internet connectivity poses an existential threat for cyber-physical systems. Securing these safety-critical systems becomes an important challenge. Cyber-physical systems often comprise several control applications that are implemented on shared platforms where both high and low criticality tasks execute together (to reduce cost). Such resource sharing may lead to complex timing behavi
Editor's notes: This article discusses self-awareness in wearable edge devices to enable real-time and long-term health monitoring. The authors use the notion of self-awareness to improve the battery life of edge wearable sensors for multimodal health and workload monitoring. This approach leads to a 27.6% lower energy consumption with less than 6% of performance loss. - Umit Y. Ogras, Arizona Sta
Epilepsy is one of the most common neurological disorders and affects over 65 million people worldwide. Despite the continuing advances in anti-epileptic treatments, one third of the epilepsy patients live with drug resistant seizures. Besides, the mortality rate among epileptic patients is 2 - 3 times higher than in the matching group of the general population. Wearable devices offer a promising
Control applications are considered to be among the core applications in cyber-physical and embedded realtime systems, for which jitter is typically an important factor. This paper investigates whether it is possible to guarantee certain amount of jitter for a given set of applications on a shared platform. The effect of jitter on the stability of control applications and its relation with the lat
Today, many control applications in embedded and cyber-physical systems are implemented on shared platforms, alongside other hard real-time or safety-critical applications. Having the resource shared among several applications, to provide hard guarantees, it is required to identify the amount of resource needed for each application. This is rather straightforward when the platform is shared among
The purpose of this study was to explore the impact of a 3-day entrepreneurship camp on nursing students’ empowerment to act entrepreneurially. Data were collected through individual semi-structured interviews with 17 nursing students conducted both before and after the camp. The data also included student drawings, as well as documents and interviews with 10 stakeholder representatives. Our findi
We introduce a novel measure of how a factor influences train delays: the excess probability of delays. Using some 50 million observations across two years of railway operations in Sweden we then investigate the role of train meets and passes in explaining dwell time delays, which are known from previous research to be behind most train delays. About 4% of observed train movements include either m
