The presence of serotonin (5-hydroxytryptamine [5-HT]) in pancreatic endocrine cells is well established. Nevertheless, recent advances are only now unraveling the signaling network involving 5-HT that partly regulates the release of hormones emanating from the islets of Langerhans. It is widely accepted that failure of the pancreatic β-cell to release sufficient amounts of insulin is the main cul

The ability to store and mobilize energy is fundamental for physiologic function. Most excess energy is stored in adipose tissue as triglycerides, which is released as free fatty acids when needed through cellular processes tightly regulated by insulin. Intact adipose cell function is essential to regulate whole-body glucose and lipid metabolism. Several studies have focused on the metabolic impac

A case‐referent study on soft tissue sarcomas (STS) was conducted, to see if previous findings regarding an association between exposure to phenoxyacetic acids or chlorophenols and this tumor type could be reproduced. Fifty‐five male STS patients were thereby compared with 220 living and 110 dead population‐based referents. Furthermore, another referent group consisting of 190 patients with anothe

In a case-control study including 237 cases with soft tissue sarcoma and 237 controls, previous jobs and exposures to different agents, including pesticides, were assessed. Exposure to phenoxyacetic acids or chlorophenols gave a statistically significant increased rate ratio (RR) of 1.80 [95% confidence interval (CI) = 1.02-3.18] for soft tissue sarcoma. Exposure to phenoxyacetic acids of all type

Utbildning för vuxna lyfts ofta fram som en lösning på en rad aktuella samhällsutmaningar. Allt från miljöfrågor till den mer övergripande målsättningen att skapa ekonomisk tillväxt. Men vuxenutbildningen har också ett tydligt demokratiskt och medborgerligt uppdrag och i denna bok utforskas detta medborgerliga uppdrag utifrån dess grundläggande antaganden, verkningssätt och konsekvenser. Det är en

Combating climate change and transitioning to fossil-free energy are two central and interdependent challenges facing humanity today. Governing the nexus of these challenges is complex, and includes multiple intergovernmental and transnational institutions. This book analyses the governance interactions between such institutions, and explores their consequences for legitimacy and effectiveness. Us

The introduction first explains the rationale and theoretical and empirical contributions of the edited volume. The book seeks to address a considerable gap of knowledge of the nature of the relationship between institutions governing the climate-energy nexus in a multilevel context. In particular, there is scant research on consequences on the legitimacy and effectiveness of governance arrangemen

The concluding chapter first summarizes some of the volume’s main results along the four evaluative themes. In terms of coherence and management, the three policy fields under scrutiny – renewable energy, fossil fuel subsidy reform and carbon pricing – are roughly marked by coordination, rather than competition or outright harmony. Regarding legitimacy, the specializations and work backgrounds of

This chapter establishes four evaluative themes that will be employed across this volume to analyze the institutional complexity of policy fields in the climate-energy nexus: coherence, management, legitimacy, and effectiveness. Coherence among institutions is conceptualized along four dimensions: convergence on an overarching core norm for the policy field, balanced coverage and distribution of m

In this paper, an investigation is done into the potential of increasing the coolant temperature of an engine to maximize the powertrain efficiency. The study takes a holistic approach by trying to optimise the combined engine and waste heat recovery system. The work was done experimentally on a Volvo 4-cylinder light duty diesel engine in combination with Rankine cycle simulations. For the study,

To the Editor: The lessons that Dr. Bailar gleaned from the recent dioxin study by Fingerhut et al. of the National Institute of Occupational Safety and Health (Jan. 24 issue)1 reached far beyond, and at times contradicted, what the authors presented.2 Moreover, Bailar did not acknowledge the growing body of evidence suggesting that low-level dioxin exposure does not present a risk of cancer in hu

Epidemiological studies on the aetiology of multiple myeloma are reviewed as a background to this population based case-control study performed in an area with a high incidence of multiple myeloma. The purpose was to identify and evaluate several suspected environmental factors in relation to this disease. A total of 275 confirmed cases diagnosed in four counties in northern Sweden during four yea

In a population-based case-control study in Sweden on multiple myeloma, the occurrence of different diseases in relatives, particularly hematologic malignancies and different types of cancer, was investigated. Through a questionnaire mailed to all living subjects, i.e. cases and controls, and to the next-of-kin for deceased subjects, information was obtained on malignant and certain other diseases

Several in vitro and in vivo studies have investigated if a magnetic resonance imaging (MRI) examination can cause DNA damage in human blood cells. However, the electromagnetic field (EMF) exposure that the cells received in the MR scanner was not sufficiently described. The first studies looking into this could be regarded as hypothesis-generating studies. However, for further exploration into th