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A distributed solute model : An extended two-pore model with application to the glomerular sieving of ficoll

One of the many unresolved questions regarding the permeability of the glomerular filtration barrier is the reason behind the marked difference in permeability between albumin and polysaccharide probe molecules such as Ficoll and dextran of the same molecular size. Although the differences in permeability have been mainly attributed to charge effects, we have previously shown that this would requi

The mystery of missing feed force — The effect of friction models, flank wear and ploughing on feed force in metal cutting simulations

Underestimated feed force is a known systematic error in cutting simulations. It is considered a consequence of inaccurate friction models, but there are indicators that friction is not the only reason for the error. In some cases, the value of Coulomb friction must be over 1.0 to compensate for the feed force and such values cause over-estimated chip thickness for example. In turning, the ploughi

Experiments of closely coupled monopoles with load matching in a random field

Recent theoretical and simulation studies reveal that closely coupled antennas with appropriately chosen impedance matching loads can yield desired characteristics of small antenna correlation coefficients and/or high received power levels. However, no experiment has been performed to verify these claims. Here, we describe an experimental setup used to investigate the correlation and received powe

Preparation of Children for urinary tract x-rays and the use of premedication

During the last few years, a more liberal use of premedication in children scheduled for Ürinary tract examinations was noted. In this retrospective study, the influence of the institution of psychological means for preparation as supplement or alternative to premedication on the incidence of cases receiving premedication was investigated. During the period from 1978 to 1982, this was followed in

Cerebellar development and very preterm birth interactions with neonatal events

AbstractThe cerebellum is an important part of the brain and in very preterm infants the cerebellum is smaller at term equivalent age compared to that of infants born at term.Hypothesis and aims: The general hypothesis is that preterm birth per se causes cerebellar underdevelopment and that certain events following preterm birth, either complications or treatments, can aggravate the underdevelopme

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The genus Draba L. is a conspicuous element of the arctic flora, comprising about 350 species worldwide which mostly are arctic-alpine polyploids. Previously, it has mainly been Draba incana L., D. norvegica Gunn., D. nivalis Liljebl., D. alpina L., D. fladnizensis Wulf., D. daurica DC., D. lactea and D. cinerea Adams that have been considered as belonging to the Icelandic flora. In this paper we

The Ambiguous Effects of Democracy on Bureaucratic Quality

Recent studies find that higher degrees of democracy are related to higher levels of bureaucratic quality. However, they only offer limited explanations for this pattern based on a unidimensional understanding of democracy. We argue that future uncertainties as perceived by the incumbent, the opposition, and voters are important for why bureaucratic reform takes place. Therefore, we expect no unif

Risk prediction of atrial fibrillation based on electrocardiographic interatrial block

Background--The electrocardiographic interatrial block (IAB) has been associated with atrial fibrillation (AF). We aimed to test whether IAB can improve risk prediction of AF for the individual person. Methods and Results--Digital ECGs of 152 759 primary care patients aged 50 to 90 years were collected from 2001 to 2011. We identified individuals with P-wave ≥120 ms and the presence of none, 1, 2,

An Unsymmetric Ligand with a N5O2 Donor Set and Its Corresponding Dizinc Complex : A Structural and Functional Phosphoesterase Model

To mimic the active sites of the hydrolytic enzyme zinc phosphotriesterase, a new dinucleating unsymmetric ligand, PICIMP (2-([2-hydroxy-5-methyl-3-(([(1-methyl-1H-imidazol-2-yl)methyl](pyridin-2-ylmethyl)amino)methyl)benzyl][(1-methyl-1H-imidazol-2-yl)methyl]amino)acetic acid), has been synthesized and characterized. The hydrolytic efficacy of the complex solution (PICIMP/ZnCl2 = 1:2) has been in

Patterns of developmental plasticity in response to incubation temperature in reptiles

Early life environments shape phenotypic development in important ways that can lead to long-lasting effects on phenotype and fitness. In reptiles, one aspect of the early environment that impacts development is temperature (termed 'thermal developmental plasticity'). Indeed, the thermal environment during incubation is known to influence morphological, physiological, and behavioral traits, some o

Bekräftelse och utmaningar - om kyrkan som välfärdsaktör

Under 2016 genomförde Svenska kyrkans forskningsenhet ett teologiskt aktionsforskningsprojekt med Mölndals pastorat. Utgångspunkten var erfarenheter från ett transitboende flyktingbarn som drevs i kommunal regi i församlingens lokaler. Detta är den andra av två artiklar (se även Svensk kyrkotidning nr 9, 2017)

Qualitative modelling of functional relationships in marine benthic communities

In order to better understand and predict the dynamics of benthic macroinvertebrate communities, we need to first define the functional components of benthic biodiversity and then provide a mechanistic description of how they interact with their abiotic environment, their basic resources and each other. These interactions should be largely controlled by readily available biological traits, making

Modeling the effects of abiotic and biotic factors on the depth distribution of Fucus vesiculosus in the Baltic Sea

The conspicuous retreat of the key species Fucus vesiculosus from the deeper parts of its former distribution area in the Baltic Sea has triggered extensive research on the factors that control its growth. Based on recently obtained knowledge on a large number of potential drivers, we developed a numerical model incorporating effects of abiotic factors on the physiological functions of photosynthe

Children's and parent's perceptions of a magnetic resonance imaging examination

The aim of this study was to describe children’s and parents’ perceptions after a magnetic resonance imaging (MRI) examination. Semistructured interviews with eight children and eight parents were conducted. The interviews were analyzed using a phenomenographical approach. Both children and parents perceived a sense of security when they received preparation/information. The children perceived tha

Challenges assessing radiation risk in image guided treatments - implications on optimisation of radiological protection

The present work explores challenges when assessing organ dose and effective dose concerning image-guided treatments. During these treatments considerable x-ray imaging is employed using technically advanced angiographic x-ray equipment. Thus, the radiation dose to organs and the related radiation risk are relatively difficult to assess. This has implications on the optimisation process, in which

The radiation dose to children from X-ray examinations of the pelvis and the urinary tract

X-ray examinations of the pelvis and the urinary tract are frequent examinations of children, in which a large part of the trunk is irradiated. The irradiated volume contains many of the most radiation sensitive organs and tissues. The absorbed dose to children during the examination was estimated from measurements with a dose-area product meter and thermoluminescent dosemeters (TLDs). Entrance su

Four evolutionary trajectories underlie genetic intratumoral variation in childhood cancer

A major challenge to personalized oncology is that driver mutations vary among cancer cells inhabiting the same tumor. Whether this reflects principally disparate patterns of Darwinian evolution in different tumor regions has remained unexplored1–5. We mapped the prevalence of genetically distinct clones over 250 regions in 54 childhood cancers. This showed that primary tumors can simultaneously f