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Biomedical Research, Medicine, and Disease

Biomedical research is the first step towards the creation of new medications and treatments that help to manage different types of health conditions and diseases. The prevention and cure of diseases would be practically impossible without such type of research. Although the drug discovery and development processes are far too costly, time-consuming, prone to failure, and have low success rate, to

Measurement-Based Wideband Maritime Channel Characterization

Maritime communication is one of the 5G vertical domains and is attracting more attention. Advanced channel models that accurately characterize the wideband maritime propagation channels are essential for the development of modern maritime communication technologies. To this end, we measured the propagation channel at 5.6GHz with a sailing boat, capturing the channel with a bandwidth of 250MHz, bo

Time–Frequency Signatures of Electronic Coherence of Colloidal CdSe Quantum Dot Dimer Assemblies Probed at Room Temperature by Two-Dimensional Electronic Spectroscopy

Electronic coherence signatures can be directly identified in the time–frequency maps measured in two-dimensional electronic spectroscopy (2DES). Here, we demonstrate the theory and discuss the advantages of this approach via the detailed application to the fast-femtosecond beatings of a wide variety of electronic coherences in ensemble dimers of quantum dots (QDs), assembled from QDs of 3 nm in d

EHD2 regulates plasma membrane integrity and downstream insulin receptor signalling events

Adipocyte dysfunction is a crucial driver of insulin resistance and type 2 diabetes. We identified EH domain-containing protein 2 (EHD2) as one of the most highly upregulated genes at the early stage of adipose tissue expansion. EHD2 is a dynamin-related ATPase influencing several cellular processes, including membrane recycling, caveolae dynamics and lipid metabolism. Here, we investigated the ro

Exposure to Neighborhood Income Inequality in Childhood and Later-Life Mortality, Sweden 1939-2015

The degree of inequality in a society may be harmful to individual health, regardless of wheresomeone is located in the income ladder. An underlying assumption in the literature is thatthere is an instant link between income inequality and individual health and most studiesconsider a contemporary correlation, assessing inequality and health just about the same pointin time. Moreover, research is l

CKD-EPI and EKFC GFR Estimating Equations: Performance and Other Considerations for Selecting Equations for Implementation in Adults

Background: New CKD-EPI and EKFC estimated GFR (eGFR) equations usingcreatinine (eGFRcr), cystatin C (eGFRcys) and both (eGFRcr-cys) have sufficientaccuracy for use in clinical practice. A better understanding of the equations, includingtheir performance in race, sex and age subgroups, is important for selection of eGFRequations for global implementation.Methods: We evaluated performance (bias and

Inclusivity in online and distance disaster education : A review of educators' views

Future exemplary education should foster inclusive and respectful learning environments to meet new challenges like digital inequality and power concentration. In the new normal of education due to COVID-19, inclusive online disaster risk reduction (DRR) education is essential. Therefore, this article aims to investigate the current status quo of inclusive online and distance DRR education and its

Hamas-Israel War: Views From Wilson Center Experts

Hamas and Islamic Jihad's surprise attack on Israel represents an unprecedented upheaval to the status quo in the region. Wilson Center experts, fellows, and alumni weigh in to analyze events transpiring on the ground in the military, diplomatic, and humanitarian dimensions. This article will be updated as the situation develops.The views expressed in these entries below are those of the authors a

Immune challenge reduces daily activity period in free-living birds for three weeks

Non-lethal infections are common in free-living animals and the associated sickness behaviours can impact crucial life-history trade-offs. However, little is known about the duration and extent of such sickness behaviours in free-living animals, and consequently how they affect life-history decisions. Here, free-living Eurasian blackbirds, Turdus merula, were immune-challenged with lipopolysacchar

Scientific collaboration amid geopolitical tensions: Global variation in responses to China engagement

A global rules-based order is in flux amid intensifying United States (US)-China geopolitical competition for economic and technological advantage. Concerns about the economic and security risks of dependency on China increasingly shape economic and political decision-making in the West. This paper looks at various national responses to the rise of China in the sphere of scientific collaboration a

Constraining the eruption history of Rangitoto volcano, New Zealand, using palaeomagnetic data

New Zealand's largest city, Auckland, is situated within the basaltic Auckland Volcanic Field (AVF). Therefore, understanding the eruption history of the local volcanoes in the field is of great importance in order to assess future hazards that they may pose. Rangitoto is the youngest and largest volcano in the AVF, although the timing of the first eruption and the duration of the volcanic activit

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Corporate Social Responsibility is used as an organizational strategy and with this power it has been established that it brings endless advantages, especially in market acceptance and growth of business image. In the country and in the department of Cochabamba, it is undergoing considerable development, growth and evolution, reaching the idea of it being used as a business strategy, to be include

Geography and environmental pressure are predictive of class-specific radioresistance in black fungi

Black fungi are among the most resistant organisms to ionizing radiation on Earth. However, our current knowledge is based on studies on a few isolates, while the overall radioresistance limits across this microbial group and the relationship with local environmental conditions remain largely undetermined. To address this knowledge gap, we assessed the survival of 101 strains of black fungi isolat

Between Sophistication and Resolution : Wise Choice

In this chapter, which draws on my earlier work on the subject, I focus on agents whose preferences violate axioms of expected utility, with violations of the Independence Axiom being my prime example. This exposes them to the threat of dynamic inconsistency in sequential choice. I consider three different policies such agents could use to secure consistency. After presenting two standard policies

Predicting structure-borne noise in cross-laminated timber buildings during conceptual design

In this study, we investigate the feasibility of using a vibration-based metric for predicting low-frequency structure-borne noise in cross-laminated timber (CLT) buildings. The overall aim here is to facilitate the conceptual design for CLT buildings in terms of estimating noise levels. Since noise levels are inherently sensitive to architectural or mechanical design changes, in the low frequency

Influenza A subtype H3N2 is associated with an increased risk of hospital dissemination – an observational study over six influenza seasons

Background: Previous studies on hospital-acquired influenza (HAI) have not systematically evaluated the possible impact of different influenza subtypes. HAI has historically been associated with high mortality, but clinical consequences may be less severe in a modern hospital setting. Aims: To identify and quantify HAI for each season, investigate possible associations with varying influenza subty

Capabilities in the shadows: An ethnographic study exploring the gendered implications of a solar electrification project in rural eastern Nepal

Access to electricity is vital for rural development in the Global South, but its impact on local power dynamics, especially gender relations, remains underexplored. This thesis examines a solar electrification project in Eastern Nepal to uncover gender-related challenges in experiencing project benefits. By applying the Capabilities Approach and Kabeer's Empowerment Theory, the research ident

At the Intersection of Mindfulness and Sustainability - An overview of the emerging field of Mindfulness within Sustainability Science

Climate change is a people-made crisis which requires a shift in our mindsets. Early studies in the field of mindfulness within sustainability science show the potential of mindfulness to influence consciousness, beliefs, and values for sustainability. However, the field is still at its early stages and scattered over various topics and methods. The aim of this thesis is to assess how the concept