A distortional hardening elasto-plastic model at finite strains suitable for modeling of orthotropic materials is presented. As a prototype material, paperboard is considered. An in-plane model is established. The model developed is motivated from non-proportional loading tests on paperboard where the paperboard is pre-strained in one direction and then loaded in the perpendicular direction. A sof

T cells are key cellular components of the adaptive immune system that play a critical role in our defense against pathogens and cancer but also contribute to pathology in the setting of chronic inflammation and autoimmunity. The thymus constitutes the body's major T cell production site, where bone marrow-derived progenitors migrate in a co-ordinated fashion through anatomically distinct cortical

Implementation of sustainability criteria, both in legal frameworks and voluntary sustainability standards, is an urgent and important issue. In the article, three less state-centric governance approaches and their capacity to be used to implement sustainability criteria have been investigated. The chosen approaches are good governance, multi-level governance and selfgovernance. Their potential st

Stroke genetics includes several topics of clinical interest, including (1) molecular genetic variations affecting risk of monogenic stroke syndromes; (2) molecular genetic variations affecting risk of common stroke syndromes, sometimes with specific effects on risk of specific main types of stroke or subtypes of ischemic and hemorrhagic stroke; (3) genetics of conditions associated with stroke ri

Objectives. The low molecular weight heparin, Dalteparin, shortens human labor time. The aim of this study was to investigate if the mechanism behind this effect involves myometrial contractility and cervical ripening and if the anticoagulative activity is necessary for its effect. Design. Experimental in vitro study. Setting. Lund University and Karolinska Institute, Sweden. Methods. The effect o

The intestinal mucosa presents a huge surface area to the external environment and the intestinal immune system is continually exposed to a wide array of foreign antigens derived from resident intestinal microbiota as well as dietary constituents, including food proteins. In order to maintain intestinal homeostasis, the intestinal immune system relies on the ability to generate tolerogenic respons

Background and purpose The Scandinavian Sarcoma Group (SSG) XIV protocol was based upon the organisations experience from 3 previous osteosarcoma trials and was considered best standard of care for patients with extremity localised, non-metastatic osteosarcoma. We report the outcome of this protocol. Patients and methods From March 2001 to April 2005, 63 patients recruited from 10 centres in Finla

Popular Abstract in Swedish Rehabilitering har sedan länge varit en viktig och naturlig del av behandlingen för personer med reumatiska sjukdomar. I denna doktorsavhandling om teambaserad rehabilitering för personer med kroniska reumatiska ledsjukdomar ges en uppdatering av kunskapsläget liksom en historisk bakgrund. De vetenskapliga resultat som redovisas i avhandlingen visar i korthet på följandThe aim of this thesis was to study outcome and evaluation of rheumatological multidisciplinary team rehabilitation programmes in patients with chronic inflammatory arthritis (CIA); rheumatoid arthritis (RA), ankylosing spondylitis, psoriatic arthritis and other spondyloarthritides, and to analyse health care utilization over the last decade in patients with RA. In Study I the outcome of an 18 da

Whole cells of the genetically engineered Saccharomyces cerevisiae strain TMB4100 (1% PGI, YMR226c) were Used as the biocatalyst for the kinetic resolution of racemic bicyclo[3.3.1]nonane-2,6-dione rac-1. The yeast's phosphoglucose isomerase activity was decreased, and the short-chain dehydrogenase/reductase encoded by YMR226c was overexpressed. This reduced the demand for the glucose to regenerat

Smoking, diabetes, male sex, hypercholesterolaemia and hypertension are well-established risk factors for the development of coronary artery disease (CAD). However, less is known about their role in influencing the outcome in the event of an acute coronary syndrome (ACS). The aim of this study was to determine if these risk factors are associated specifically with acute myocardial infarction (MI)

This paper presents a complete characterization and solution to microphone position self-calibration problem for time-of-arrival (TOA) measurements. This is the problem of determining the positions of receivers and transmitters given all receiver-transmitter distances. Such calibration problems arise in application such as calibration of radio antenna networks, audio or ultra-sound arrays and WiFi

Effectiveness of management would be seen when we have to ensure the accuracy of the output. This is possible if the model predictions are done based on the behavior of desired phenomena in the real world, using appropriate organizing data in a Geo-spatial Information System. Therefore all the aspects of a phenomenon must be considered. But most Geo-spatial Information Systems' databases use a ver

The structures of interfacial layers formed from mixtures of comb polymers, comprising a high charge density cationic backbone and poly(ethylene oxide) (PEO) side-chains, with the anionic surfactant sodium dodecyl sulfate (SDS) at the silica/water interface, have been determined using neutron reflectivity measurements. The use of mixtures in which only the isotopic composition of the surfactant is

Systemic lupus erythematosus (SLE) is an autoimmune rheumatic disorder characterized by inflammation in several organ systems. SLE patients have an impaired ability to clear dying cells which leads to the exposure of several nuclear antigens which might break self tolerance. Autoantibodies directed against the nuclear antigens will form large immune complexes (ICs) which are central in the immunop

Abstract. In previous work we have studied the effects of electromagnetic fields upon the promotion of growth of tumours from two different rat glioma cell lines, RG2 and N32, inoculated in the brains of Fischer 344 rats. No promotions of tumour growth due to the EMF could be demonstrated in large series of animals as compared to their matched controls. In the present study we have utilized a newl

We demonstrate the potential of infrared degenerate four-wave mixing (IR-DFWM) as a tool for non-intrusive in situ spatially resolved detection of CH3Cl in reactive hot gas flows especially feasible for applications to biomass combustion and gasification. IR-DFWM spectra of CH3Cl, by probing ro-vibrational transitions belonging to the fundamental stretching modes v(1) and v(4), have been successfu

A recent study reported a large increase in the number of meniscal procedures from 2000 to 2011 in Denmark. We examined the nation-wide distribution of meniscal procedures performed in the private and public sector in Denmark since different incentives may be present and the use of these procedures may differ from region to region.