Aims/hypotheses: Smoking and use of smokeless tobacco (snus) are associated with an increased risk of type 2 diabetes. We investigated whether smoking and snus use increase the risk of latent autoimmune diabetes in adults (LADA) and elucidated potential interaction with HLA high-risk genotypes. Methods: Analyses were based on Swedish case–control data (collected 2010–2019) with incident cases of L

Syftet med studien var att undersöka upplevelsen av att erfara sexuella biverkningar i samband med antidepressiv läkemedelsbehandling samt vilka strategier personer använder sig av för att hantera dem. Studien syftade även att undersöka hur sexuella skript och normer beskrivs inverka på upplevelsen av att hantera sexuella biverkningar, samt hur vården kan hjälpa denna patientgrupp ytterligare. DatThe aim of this study was to examine the experience of sexual side effects during antidepressant medical treatment and which strategies people use to cope with them. The study also aimed to explore how sexual scripts and norms are described as affecting the experience of coping with sexual side effects, and how health care can further support this group of patients. Data was collected through semi

Soil microorganisms regulate the decomposition of organic matter. However, microbial activities can also be rate-limited by the resource in lowest supply. Arctic ecosystems are being exposed to pronounced climate warming, with arctic greening, treeline advance and shrubification resulting in increased plant-derived carbon (C) inputs to soils, and faster rates of decomposition releasing mineral nut

Background: Different tau biomarkers become abnormal at different stages of Alzheimer’s disease (AD), with CSF p-tau typically being elevated at subthreshold levels of tau-PET binding. To capitalize on the temporal order of tau biomarker-abnormality and capture the earliest changes of tau accumulation, we selected a group of amyloid-β-positive (A+) individuals with elevated CSF p-tau levels but ne

Plastic film mulching (PFM) in the cropland may alter biophysical conditions for crop growth, which may not be accounted for in existing stomatal conductance models. This can affect the accuracy of carbon–nitrogen-water cycle simulations for the soil-crop systems and hamper our understanding of internal mechanisms that control plant leaf stomatal conductance (gsw). To evaluate the simulations of P

Previous genome-wide association studies (GWASs) of stroke - the second leading cause of death worldwide - were conducted predominantly in populations of European ancestry1,2. Here, in cross-ancestry GWAS meta-analyses of 110,182 patients who have had a stroke (five ancestries, 33% non-European) and 1,503,898 control individuals, we identify association signals for stroke and its subtypes at 89 (6

OBJECTIVES: Rituximab has become the cornerstone of induction treatment in ANCA-associated vasculitis (AAV). B cell depletion may increase the risk of hypogammaglobulinemia, potentially leading to severe infections. This study aims to assess factors associated with hypogammaglobulinemia in AAV patients treated with rituximab.METHODS: This retrospective cohort study included AAV patients treated wi

Utsatta områden har varit föremål för debatt sedan polismyndigheten införde klassificeringen 2015. Syftet med klassningen var initialt att få en nationell lägesbild över kriminella nätverks påverkan i lokalsamhällen. Idag finns totalt 61 områden som klassificeras som utsatta där cirka 5 % av Sveriges befolkning är bosatt. Polismyndighetens lista över utsatta områden är offentlig och har bemötts meVulnerable areas have been the subject of debate since the Swedish police authority introduced the classification in 2015. Today there are a total of 61 areas classified as vulnerable and approximately 5 % of the Swedish population lives in a vulnerable area. The police authority updates and publishes a list of vulnerable areas every second year. The fact that the list is made public has been a su

Background: Rectal washout (RW) is routinely performed during anterior resection (AR) for rectal cancer to reduce local recurrence (LR), although is sometimes not performed during minimally invasive surgery (MIS) procedures due to technical challenges and time consumption. The aim was to investigate the impact of RW on the oncological outcome after AR for rectal cancer in a registry cohort. Method

Om Nat Turners uppror.

Bakgrund: Aktivitetsidentiteten byggs upp av aktiviteter och roller som ingår i människor liv, den formas över tid av både negativa och positiva händelser. Vid ett fängelsestraff påverkas aktivitetsidentiteten eftersom aktiviteter och dagliga rutiner förändras. En förståelse för personers utveckling av aktivitetsidentitet går att studera genom tre underkategorier “uppbyggnad av aktivitetsidentitetBackground: Occupational identity is constructed of activities and roles that is a part of human life, it is formed over time of both negative and positive experiences. When a person is imprisoned, their occupational identity is impacted because of the change in their everyday life activities and daily routines. The knowledge of a person's occupational identity progress could be studied throug

In Sweden, the child perspective in social services has become greater and more acknowledged over the years. Today, social services have a child perspective in which the children's best always should be the main issue in an investigation. However, this also means that the social service workers must adapt to the working conditions in which they can feel compassion, anger, and sadness, all whil

Den 9 september 2022 överlämnade Lunds universitet kraniet av en samisk man till Arjeplogs sameförening. Detta var den första återlämningen av en samisk kvarleva ur Lunds universitets anatomiska samling ...

The encapsulation of colloidal lead halide perovskite nanocrystals within silica (SiO2) is one of the strategies to protect them from polar solvents and other external factors. Here, we demonstrate the overcoating of CsPbBr3 perovskite nanocrystals with silica by exploiting the anhydride-induced transformation of Cs4PbBr6 nanocrystals. CsPbBr3@SiO2 core–shell nanocrystals are obtained after (i) a

Bakgrund: Dagens ambulanssjukvård är i en ständig utveckling och antalet ambulansuppdrag har successivt ökat och det blir alltmer vanligare för ambulanspersonal att hänvisa patienter till en annan vårdnivå än sjukhus då behovet av akutsjukvård inte behövs. Trots att detta arbetssätt blivit alltmer vanligare är forskningsläget kring patienters erfarenheter vid mötet med ambulanspersonal när de hänv

PurposeGermline genetic testing for BRCA1 and BRCA2 variants has been a part of clinical practice for >2 decades. However, no studies have compared the cancer risks associated with missense pathogenic variants (PVs) with those associated with protein truncating (PTC) variants.MethodsWe collected 582 informative pedigrees segregating 1 of 28 missense PVs in BRCA1 and 153 pedigrees segregating 1 of