Published 26 November 2019 Half as many diagnosed with depression, a delayed manifestation of Parkinson’s, a reduced risk of developing vascular dementia - but not Alzheimer’s. These connections were discovered by researchers when they compared 200 000 people who had participated in a long-distance cross-country ski race between 1989 and 2010 with a matched cohort of the general population. The re

https://www.multipark.lu.se/article/skiers-had-lower-incidence-depression-and-vascular-dementia-not-alzheimers - 2025-04-03

Published 13 December 2019 Neuroscientists at Lund University in Sweden have developed a new technology that engineers the shell of a virus to deliver gene therapy to the exact cell type in the body that needs to be treated. The researchers believe that the new technology can be likened to dramatically accelerating evolution from millions of years to weeks.Read the full article here

https://www.multipark.lu.se/article/high-tech-method-uniquely-targeted-gene-therapy-developed - 2025-04-03

Published 4 March 2020 Diagnosing Alzheimer's disease is often difficult, as several other conditions can cause similar symptoms. Researchers at Lund University in Sweden have now discovered a blood marker that can accurately diagnose Alzheimer’s in the early stages of the disease.Read the full article here

https://www.multipark.lu.se/article/blood-test-enables-early-diagnosis-alzheimers-disease - 2025-04-03

Published 1 April 2020 To understand what happens in the brain when Alzheimer's disease develops, researchers need to be able to study the molecular structures in the neurons affected by Alzheimer's disease. Researchers at Lund University in Sweden have tested a new imaging method for this purpose. The research is published in the journal Advanced Science.Read the full article here

https://www.multipark.lu.se/article/new-imaging-method-sheds-light-alzheimers-disease - 2025-04-03

Published 6 May 2020 Hela Sverige riskerar att få en liknande situation som den på Stockholms äldreboenden om vi inte gör mer för att minska spridningen av viruset på boendena. Det skriver flera debattörer, som lägger fram fem förslag.Länk till artikel

https://www.multipark.lu.se/article/detta-bor-goras-att-skydda-aldre-pa-boenden - 2025-04-03

Published 26 May 2020 Stem cell researchers at Lund University in Sweden have developed a new research model of the early embryonic brain. The aim of the model is to study the very earliest stages of brain to understand how different regions in the brain are formed during embryonic development. With this new insight, researchers hope to be able to produce different types of neural cells for the tr

https://www.multipark.lu.se/article/new-method-provides-unique-insight-development-human-brain - 2025-04-03

Published 1 June 2020 Toxic versions of the protein tau are believed to cause death of neurons of the brain in Alzheimer’s disease. A new study published in Nature Communications shows that the spread of toxic tau in the human brain in elderly individuals may occur via connected neurons. The researchers could see that beta-amyloid facilitates the spread of toxic tau.Read the full article here

https://www.multipark.lu.se/article/how-toxic-protein-spreads-alzheimers-disease - 2025-04-03

Published 18 June 2020 From the coordinator:As we approach Midsommar, we in MultiPark can reflect on the extraordinary last few months and hope that our environment can return back more to meetings, seminars and productive exchanges after the summer. Although neurodegenerative diseases were less in the news because of Covid-19, people with Parkinson and Alzheimer’s diseases were however more affec

https://www.multipark.lu.se/article/message-coordinator - 2025-04-03

Published 26 June 2020 Neuroscientists and stem cell researchers at Lund University in Sweden have developed a research model that allows studying human hippocampal neurons, the brain cells primarily affected by Alzheimer’s disease pathology. The study has been published in Stem Cell Reports.Read the full article here.See also interview with Alzheimerfonden regarding the study. 

https://www.multipark.lu.se/article/new-research-paves-way-developing-therapies-could-slow-down-alzheimers - 2025-04-03

Published 11 August 2020 A new blood test demonstrated remarkable promise in discriminating between persons with and without Alzheimer’s disease and in persons at known genetic risk may be able to detect the disease as early as 20 years before the onset of cognitive impairment, according to a large international study published today in the Journal of the American Medical Association (JAMA) and si

https://www.multipark.lu.se/article/new-blood-test-shows-great-promise-diagnosis-alzheimers-disease - 2025-04-03

Published 20 August 2020 Around 20,000 people have been diagnosed with Parkinson's disease in Sweden. Today, there is no imaging method of changes in the brain that are believed to cause the disease. Researchers at Skåne University Hospital and Lund University have received nearly SEK 7 million from the Michael J Fox Foundation to develop an imaging technique that can more accurately detect and tr

https://www.multipark.lu.se/article/millions-michael-j-fox-foundation-improve-diagnosis-parkinsons - 2025-04-03

Published 6 October 2020 Aducanumab was compared, in a blinded study, to three clinical-stage antibodies using chemical kinetics. The publication describes the use of chemical kinetic analysis to assess the mechanisms of action of four clinical stage anti-Aβ antibodies: aducanumab (Biogen), gantenerumab (Roche), bapineuzumab (Elan) and solanezumab (Eli Lilly). The results provide unique insights i

https://www.multipark.lu.se/article/four-ab-antibodies-only-aducanumab-stems-tide-toxic-oligomers - 2025-04-03

Published 2 December 2020 A new study from Lund University in Sweden shows that validated biomarkers can reveal an individual’s risk of developing Alzheimer’s disease. Using a model that combines the levels of two specific proteins in the blood of those with mild memory impairment, the researchers are able to predict the risk of developing Alzheimer’s. The researchers have also developed an app th

https://www.multipark.lu.se/article/app-predicts-risk-developing-alzheimers - 2025-04-03

Published 14 December 2020 The brain has its own cleaning system that removes harmful substances while we sleep and protects it from diseases such as Alzheimer’s disease. Neuroscientists at Lund University in Sweden have now imaged the cleaning system in 3D, indicating that it is substantially more developed than previously thought. Read the full article here.

https://www.multipark.lu.se/article/watch-cleaning-system-brain-captured-3d-footage - 2025-04-03

Published 17 December 2020 The Swedish Basal Ganglia Society We are happy to announce the formation of SWEBAGS - the Swedish Basal Ganglia Society. SWEBAGS is a nationwide non-profit organization providing a platform for scientific discussion and education in basal ganglia-related research. We aim to foster multidisciplinary collaborations across biological scales and methodological approaches. Al

https://www.multipark.lu.se/article/swebags-launched - 2025-04-03

Published 11 January 2021 A research group from Lund Stem Cell Center aims to understand a specific type of neuron that could underlie several brain disorders including schizophrenia, epilepsy and autism, and are developing exciting new strategies to treat them. Read the full article here.

https://www.multipark.lu.se/article/restoring-neural-networks-and-understanding-brain-disorders - 2025-04-03

By Martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 5 February 2021 Researchers at Lund University in Sweden believe they have identified a gene variant that can cause cerebral small vessel disease and stroke. The study is published in Neurology Genetics. Read more about this discovery.  Article in Neurology Genetics MAP3K6 Mutations in a Neurovascular Disease Causi

https://www.multipark.lu.se/article/new-gene-variant-linked-stroke - 2025-04-03

Published 23 February 2021 Gesine Paul-Visse, Associate Professor and last author of the study. Overexpression of the Parkinson-related protein, α-synuclein, leads to blood-brain barrier leakage and pericyte activation in mice. A study published in Scientific Reports identifies pericytes as potential target cells for early interventions. Parkinson’s disease is a movement disorder caused by the acc

https://www.multipark.lu.se/article/pericytes-link-between-parkinson-related-protein-and-blood-brain-barrier-disruption - 2025-04-03

Published 11 March 2021 A high power microscopy image of a neuron (blue) in which the epigenetic silencing of ERVs are lost, resulting in abundant ERV proteins (red). Photo credit: Marie Jönsson. Researchers from Lund Stem Cell Center highlight the importance of controlling viral elements that reside in the genome and how their activation during development may contribute to brain disorders later

https://www.multipark.lu.se/article/activation-ancient-viruses-during-brain-development-causes-inflammation - 2025-04-03

By emma [dot] renman [at] innovation [dot] lu [dot] se (Emma Renman) - published 6 May 2024 Petter Pilesjö, Abdulghani Hasan, and Andreas Persson were tired of the feeling of writing articles and presenting at conferences without anything happening. Learn how they went from research results to making use of their findings by starting the company PluvioFlow. Petter Pilsjö is a Professor at Lund Uni

https://www.innovation.lu.se/en/article/they-started-company-spread-their-research-findings-we-need-get-better-handling-floods - 2025-04-03